Renal p53 expression in FA induced injury in mice. by Dev Kumar (681481)

“…<p>Representative images of p53 immunostaining (green: FITC and red: Propidium iodide) showing decrease in protein expression in PDTC treated mouse kidney at 48 hr after FA treatment (A–L). n = 4; Magnification: 40X, 100X, and 400X with scale bar: 100 µm, 100 µm and 50 µm respectively.…”

Supplementary Material for: Long-term trends in incidence, attack rates, and early case-fatality of spontaneous intracerebral hemorrhage. Dijon Stroke Registry (1985-2022) by figshare admin karger (2628495)

“…A slight decrease was observed during period 2017-2022 (18.9/100,000/year, IRR: 0.81; 95% CI: 0.61-1.06, p=0.11). …”

Data_Sheet_1_Integrating Ligand and Target-Driven Based Virtual Screening Approaches With in vitro Human Cell Line Models and Time-Resolved Fluorescence Resonance Energy Transfer A... by Gurbet Tutumlu (8691720)

“…In the first approach, a molecular docking and filtering approach is used to rank compounds based on their docking scores and only a few top-ranked molecules are selected for further long (100-ns) molecular dynamics (MD) simulations and in vitro tests. …”

Data_Sheet_3_Integrating Ligand and Target-Driven Based Virtual Screening Approaches With in vitro Human Cell Line Models and Time-Resolved Fluorescence Resonance Energy Transfer A... by Gurbet Tutumlu (8691720)

“…In the first approach, a molecular docking and filtering approach is used to rank compounds based on their docking scores and only a few top-ranked molecules are selected for further long (100-ns) molecular dynamics (MD) simulations and in vitro tests. …”

Data_Sheet_2_Integrating Ligand and Target-Driven Based Virtual Screening Approaches With in vitro Human Cell Line Models and Time-Resolved Fluorescence Resonance Energy Transfer A... by Gurbet Tutumlu (8691720)

“…In the first approach, a molecular docking and filtering approach is used to rank compounds based on their docking scores and only a few top-ranked molecules are selected for further long (100-ns) molecular dynamics (MD) simulations and in vitro tests. …”

Dopaminergic differentiation deficit persists at later stages in <i>Dkk1</i> mutants. by Diogo Ribeiro (230483)

“…Scale bar = 100 µm. (B) A 30% decrease in the number of dopaminergic neurons was detected at this stage (mean ± s.e.m- <b><i>Wt</i></b><b>:</b> 10640±1301 N = 4; <b><i>Dkk1^<b>+/−</b></i></b><b>:</b> 7262±616.9 N = 3). …”

PAMs ameliorates the psoriasis-like symptoms and skin inflammation in imiquimod-induced mice. by Rongkun Dou (1887913)

“…<p>A: Histopathological investigation in each group (×100). …”

Figure 3 by Michael S. Akhras (60473)

“…<b>C</b>) DNA amounts were set at 100 ng for HPV-45 plasmid and 1 nanogram for HPV-59 plasmid, which was observed as a ∼3-fold decrease in signal intensity. …”

Hierarchically clustered ANIm heatmap across Set-R combined with phylogenetic information reveals unknown species diversity within the ACB clade. by Bardya Djahanschiri (6203681)

“…These clusters and cutoffs are typically used for bacterial species delineation. In the ACB clade, we observe a large and distinct cluster with 98–100% sequence identity (rounded) for the <i>A</i>. …”

TF function predicted from regulatory parameters <i>α</i> and <i>β</i>. by Md Zulfikar Ali (11965544)

“…Black contours mark FC_max = 1 and subsequent contours represent 100–fold increase or decrease in FC_max. …”

Deterministic sensitivity analysis. by Katharina Wahedi (7136459)

“…Bars on the right indicate an increase of ICER, bars on the left show a decrease of ICER. Changes resulting from increasing the parameters are represented by green bars while those resulting from a decrease of parameters are shown in red.…”

Resveratrol Protects Chondrocytes from Apoptosis via Altering the Ultrastructural and Biomechanical Properties: An AFM Study by Hua Jin (320594)

“…CCK-8 assay showed that 100 μM RV significantly prevented SNP-induced cytotoxicity. …”

Lithiation-Induced Embrittlement of Multiwalled Carbon Nanotubes by Yang Liu (4829)

Lithiation-Induced Embrittlement of Multiwalled Carbon Nanotubes by Yang Liu (4829)

GCP proliferation induced by WNT3 is not dependent on the BMP pathway. by Sandrine L. Anne (489755)

“…<p>(<i>A</i>) WNT3 and BMPs (BMP2, BMP4, BMP6, and BMP7) cooperated to decrease proliferation of GCPs as measured by [³H]-Thymidine incorporation assay. …”

HIV-1 envelope glycoprotein gp41 schematic and structure of the 2F5 antibody-peptide complex. by Javier Guenaga (150719)

“…Residues at the apex of the CDRH3 in magenta (_100ALFGV_100D) were not altered. …”

Table_1_Study on the additional financial burden of breast cancer disease on cancer patients and their families. Financial toxicity in cancer.XLSX by Eduardo J. Fernandez-Rodriguez (18963088)

“…However, after being diagnosed with breast cancer, there is a significant income decrease of 15.91%, resulting in a reduced average annual income of 16785.98 euros. …”

Possible Increase in Serum FABP4 Level Despite Adiposity Reduction by Canagliflozin, an SGLT2 Inhibitor by Masato Furuhashi (85555)

“…Treatment with canagliflozin significantly decreased adiposity and levels of fasting glucose and HbA1c but increased average serum FABP4 level by 10.3% (18.0 ± 1.0 vs. 19.8 ± 1.2 ng/ml, P = 0.008), though elevation of FABP4 level after treatment was observed in 26 (66.7%) out of 39 patients. …”

<i>ACVR2</i> promoter hypermethylation and LOH in colon cancer specimens and the MSS HT29 cell line and correlation of <i>ACVR2</i> promoter hypermethylation and loss of <i>ACVR2</... by Barbara Jung (155690)

“…<p>A) ACVR2 promoter with map of positioning of MSP primers B) Using a CpG islands search program, we identified the CpG islands within the <i>ACVR2</i> promoter based upon following stringent criteria: ∼CG percentage>55%; observed CpG/expected CpG >0.65; length >500 bp. …”

Supplementary Material for: The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in... by Reuther C. (3593810)

“…The small molecule NVP-CGM097 is a novel MDM2 inhibitor. We investigated MDM2 inhibition as a target in neuroendocrine tumor cells in vitro. …”