Flexible Reaction Pocket on Bulky Diphosphine–Ir Complex Controls Regioselectivity in <i>para</i>-Selective C–H Borylation of Arenes by Brandon E. Haines (1312221)

“…It is shown that an increase in the steric bulk of the ligand by introducing bulkier 3,5-substituents to the phenyl rings of the diarylphosphino groups of <b>L1</b> <i>decreases</i> the <i>para</i>-selectivity. This computational prediction was validated by experiments on C–H borylation of trimethyl­(phenyl)­silane by using the 3,5-di-<i>tert</i>-butylphenyl analogue of MeO-BIPHEP (<b>L3</b>) as a diphosphine ligand that showed a <i>decrease</i> in <i>para</i>/<i>meta</i> ratio from 88:12 (<b>L1</b>) to 50:50 (<b>L3</b>). …”

Effect of OP2113 on ROS/H₂O₂ production by isolated rat heart mitochondria. by Dominique Detaille (3768979)

Predictive value of clinical and laboratory features for the main febrile diseases in children living in Tanzania: A prospective observational study by Olga De Santis (3993422)

“…</p><p>Conclusion</p><p>A better understanding of the relative performance of these predictors might be of great help for clinicians to be able to better decide when to test, treat, refer or simply observe a sick child, in order to decrease morbidity and mortality, but also to avoid unnecessary antimicrobial prescription. …”

DataSheet_1_Effects of lipids on the rate-limiting steps in the dark-to-light transition of Photosystem II core complex of Thermostichus vulcanus.docx by Melinda Magyar (18191443)

“…<p>In our earlier works, we have shown that the rate-limiting steps, associated with the dark-to-light transition of Photosystem II (PSII), reflecting the photochemical activity and structural dynamics of the reaction center complex, depend largely on the lipidic environment of the protein matrix. Using chlorophyll-a fluorescence transients (ChlF) elicited by single-turnover saturating flashes, it was shown that the half-waiting time (Δτ_1/2) between consecutive excitations, at which 50% of the fluorescence increment was reached, was considerably larger in isolated PSII complexes of Thermostichus (T.) vulcanus than in the native thylakoid membrane (TM). …”

Expression of ManB and GusA in <i>L</i>. <i>casei</i> MCJΔ1. by Jinzhong Lin (189430)

“…<i>casei</i> MCJΔ1/pELX1-ManB transformant were 0.2, 0.5, 1.0, 1.8, 2.9, 4.3, 5.0 and 6.7, and those of <i>L</i>. <i>casei</i> MCJΔ1/pELX1-GusA transformant were 0.2, 0.5, 1.0, 2.2, 3.6, 4.6, 5.8 and 6.6, respectively. …”

Western blot detection of ManB and GusA in <i>L</i>. <i>casei</i>. by Jinzhong Lin (189430)

“…<i>casei</i> MCJΔ1 transformant at different cell densities (OD₆₀₀ = 1.0, 1.8, 2.9, 4.3, 5.0 and 6.7). (<b>B</b>) Western blot of His-tagged GusA from the <i>L</i>. …”

Membrane permeability of niosomes and liposomes. by Rianne Bartelds (1343631)

“…E: Stability of liposomes and niosomes filled with the fluorescent dye calcein (5 mM) after osmotic upshift by glycerol. At 50s (indicated by a black arrow), 0.667 M glycerol was added (osmolarity comparable to that of 0.4M KCl); line color as indicated under B. …”

The effects of metformin, donepezil, insulin glargine, and glibenclamide on serum biomarkers: Glucose, HbA1c, lipid profile, IL6, TNFa, amyloid β 42, total plasma tau, and NFL. by Shatw Khalid Ali (13020885)

Effect of ELX-02 in <i>CTNS</i>^{<i>Y226X/Y226X</i>} mice. by Emma J. Brasell (8081969)

“…<p><b>A</b>. Half-cystine measurements show decrease pathologic accumulation in kidneys of <i>Ctns</i>^{<i>Y226X/Y226X</i>} mice treated with 7 injections of ELX-02 (10 mg/kg) over a 3-week period. …”

CTNS protein and mRNA levels in human fibroblasts. by Emma J. Brasell (8081969)

Analysis of (-)-epigallocatechin gallate (2.5 mmol/L) upon titration with salivary mucin. by Judith Delius (3813784)

Anisotropic Tuning of Graphite Thermal Conductivity by Lithium Intercalation by Xin Qian (714942)

“…We found that intercalation of lithium has an anisotropic effect on tuning the thermal conductivity: the thermal conductivity in the basal plane decreases monotonically from 1232 W/m·K of pristine graphite to 444 W/m·K of the fully lithiated LiC₆, while the thermal conductivity along the <i>c</i>-axis decreases first from 6.5 W/m·K for graphite to 1.3 W/m·K for LiC₁₈ and then increases to 5.0 W/m·K for LiC₆ as the lithium composition increases. …”

Dung Beetles along a Tropical Altitudinal Gradient: Environmental Filtering on Taxonomic and Functional Diversity by Cássio Alencar Nunes (2852327)

“…The altitudinal gradient ranged from 800 up to 1400 m a.s.l. and we collected dung beetles at every 100 m of altitude. …”

Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma by Bo Li (112195)

“…Herein, we report the structure-guided development of a series of covalent inhibitors of FAK. These new compounds displayed highly potent inhibitory potency against FAK enzymatic activity with IC₅₀ values in the nanomolar range. …”

The productivity of a research unit as a function of the funding <i>x</i>. by Miguel Navascués (164739)

Presentation1_The impact of Climate Change on extreme winds over northern Europe according to CMIP6.pdf by Xiaoli Guo Larsén (12502987)

“…We obtain the possible effect of climate change through the comparison of the extreme wind parameters, including the 50-year wind and the 95%-percentile of the wind speed, and the change in turbine class at 50 m, 100 m and 200 m, between a near future period (2020–2049) and the historic period (1980–2009). …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Validation of NUMB as a target for <i>miR-146a</i>. by Pei-Shi Hung (489732)

Image_1_Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.TIFF by Wenfei Xia (5055482)