Genome-wide CRISPRi screen to reveal proteins and pathways impacting PF8503 toxicity in K562 cells. by Nadège Liaud (6470615)

“…<p>(A) Overview of the CRISPRi experiment, carried out using K562 cell lines expressing dCas-KRAB and the hCRISPRi-v2 library. …”

Fluoxetine inhibits the differentiation of hypothalamic neuroprogenitor cells. by Lígia Sousa-Ferreira (221509)

“…Representative confocal photomicrographs for mature neurons marker Neu-N (green) (<b>A</b>). Fluoxetine decreases the percentage of Neu-N positive cells and the incubation with Trk receptors inhibitor K252a (24 h) partially reverses this effect (<b>B</b>). …”

Generation of multilayered electrospun vascular scaffolds. by D. Radakovic (4509652)

“…The inset in depicts the mean fluorescence intensity ± standard deviation (SD) in a higher magnification of the indicated region (n = 3).…”

Ca2+-dependent release of ATP can be evoked in the cortical astrocytes of the wild-type but not of the dn-SNARE mice. by The PLOS Biology Staff (614265)

“…(B) Inhibition of vacuolar H-ATPase in the astrocytes with Bafilomycin A1 (1 µM for 2 h) dramatically decreased both the amplitude and frequency of phasic currents. …”

SWR-associated increase in neuronal firing rates is weakened in APP/PS1 mice in both dCA1 and vCA1. by Udaysankar Chockanathan (18510288)

“…(M) In vCA1, the SWR log₁₀(modulation index) was significantly decreased in APP/PS1 mice relative to C57BL/6 controls (mean ± std: C57BL/6 = 3.50 ± 1.49, APP/PS1 = 2.28 ± 1.70 Hz, p < 10⁻⁶, two-sided Wilcoxon rank-sum test, n_C57BL/6 = 689 neurons, n_APP/PS1 = 651 neurons).…”

Analysis of tumour vasculature with the addition of more HT groups. by Deepa Sharma (278210)

“…The vasculature becomes less evident in the treated groups, with decreasing numbers of stained blood vessels. Images were taken at a 20x objective lens, and the scale bar denotes ~50μm. …”

Effects of therapeutic and aerobic exercise programs in temporomandibular disorder-associated headaches by Paula Manuela Mendes MOLEIRINHO-ALVES (12659778)

“…The headache intensity scores (0.3 [95% CI: -0.401, 1.068]), (0.0 [95% CI: -0.734, 0.734]) and HIT-6 (50.7 [95% CI: 38.008, 63.459]), (49.5 [95% CI: 36.808, 62.259]), significantly decreased in G1 and G2 at A1. …”

Image_1_Deep brain stimulation in Early Onset Parkinson's disease.JPEG by Patricia Krause (9398407)

“…These improvements were accompanied by a significant 59% LEDD reduction (p < 0.001), a significant 6.6 ± 16.1 points reduction of impulsivity (p = 0.02; n = 35) and a significant 30 ± 50% improvement of QoL (p = 0.01). …”

Graphene Oxide Grid Preparation by Thomas G. Martin (2619529)

“…Graphene-oxide is commercially available as solubilized flakes in sizes ranging from less than 0.5 µm to bigger than 50µm. This allows for a simple grid preparation in a few minutes without expensive equipment.…”

Table_1_New insights into the cortex-to-stele ratio show it to effectively indicate inter- and intraspecific function in the absorptive roots of temperate trees.docx by Xiangjuan Liu (618000)

Table_1_Clinical Outcomes of Permanent Left Bundle Branch Area Pacing in Patients With Left Bundle Branch Block and Left Ventricular Ejection Fraction >35 vs. ≤35%.XLS by Zhixin Jiang (11992688)

“…</p>Methods and Results<p>Thirty-six consecutive patients with LBBB and LVEF <50% were enrolled. All patients were followed up for a mean of 6 months. …”

Table 1_Species diversity and risk factors of gastrointestinal nematodes in smallholder dairy calves in Kenya.docx by Sylvia Cheptoo (22040249)

“…Co-infections were common, accounting for 69.5% of all infections, with two (40.1%), three (26.9%), and four-species combinations (19.8%) predominating. Male calves showed a significant association with both increased FEC and smaller heart girth, while FEC decreased with age. …”

Image 1_Species diversity and risk factors of gastrointestinal nematodes in smallholder dairy calves in Kenya.tiff by Sylvia Cheptoo (22040249)

“…Co-infections were common, accounting for 69.5% of all infections, with two (40.1%), three (26.9%), and four-species combinations (19.8%) predominating. Male calves showed a significant association with both increased FEC and smaller heart girth, while FEC decreased with age. …”

Table_1_New parameterization of air-sea exchange coefficients and its impact on intensity prediction under major tropical cyclones.docx by Woojeong Lee (14133690)

Image_1_New insights into the cortex-to-stele ratio show it to effectively indicate inter- and intraspecific function in the absorptive roots of temperate trees.jpg by Xiangjuan Liu (618000)

Body composition from 18 to 22 years and pulmonary function at 22 years—1993 Pelotas Birth Cohort by Paula Duarte Oliveira (6685202)

Parallel activation of ERK2 and JNK1 contributes to TNF-α-induced IL-8 expression. by Shinichi Namba (3350288)

“…<p>(A) Expression of phosphorylated JNK1 (p-JNK1), total JNK1 (t-JNK1), phosphorylated ERK2 (p-ERK2), total ERK2 (t-ERK2), and β-actin were detected by western blotting in cells transfected with ERK2 siRNA and subsequently stimulated with or without TNF-α (50 ng/mL) for 15 min (upper panel). β-actin was used as an internal standard. …”

Supplementary Material for: Physical Activity, Screen Time, and Sleep Duration of Children Aged 6–9 Years in 25 Countries: An Analysis within the WHO European Childhood Obesity Sur... by Whiting S. (9907584)

“…Pooled analysis showed that: 79.4% were actively playing for >1 h each day, 53.9% were not members of a sport or dancing club, 50.0% walked or cycled to school each day, 60.2% engaged in screen time for <2 h/day, and 84.9% slept for 9–11 h/night. …”

Loss of SOX9 Expression Is Associated with PSA Recurrence in ERG-Positive and PTEN Deleted Prostate Cancers by Christoph Burdelski (709969)

“…While no unequivocal changes in the SOX9 expression levels were found in different stages of ERG-negative cancers, a gradual decrease of SOX9 paralleled progression to advanced stage, high Gleason grade, metastatic growth, and presence of PTEN deletions in ERG-positive cancers (p<0.0001 each). …”

Image 1_Epidemiological characteristics of severe fever with thrombocytopenia syndrome and the relationship with meteorological factors in Jiangsu Province, China.tif by Yuhao Tao (22152865)

“…However, excessively high temperatures can also lead to a decrease in the incidence of SFTS. Targeted strategies and measures should be taken to prevent its spread.…”