Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response by Xue, Mingzhan

“…Herein we assessed the effect of high glucose concentration and related increased cellular MG on activation status of IRE1α, PERK and ATF6. Human aortal endothelial cells and HMEC-1 microvascular endothelial cells were incubated in low and high glucose concentration to model blood glucose control, with increase or decrease of MG by silencing or increasing expression of glyoxalase 1 (Glo1), which metabolizes MG. …”
Get full text
Get full text
Get full text

Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus by Dimitrios, Patoulias

“…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …”
Get full text
Get full text
Get full text

Reduced graphene oxide impregnated gelma hydrogel promotes angiogenic activity in chick embryo model by Rehman, Syed Raza ur

“…Statement of Purpose: Non-healing or slow healing of chronic wounds is among the serious complications of diabetes. Decrease in blood supply along with oxygen, nutrients and growth factors leads to reduced proliferation and migration of fibroblasts and keratinocyte cells as well as decrease in angiogenesis and collagen deposition in diabetic wounds [1]. …”
Get full text
Get full text
Get full text

Electrical characteristics and density of states of thin-film transistors based on sol-gel derived ZnO channel layers with different annealing temperatures by Wang S.

Get full text
Get full text

Evacuation under flooded conditions: Experimental investigation of the influence of water depth on walking behaviors by Dias, Charitha

“…Three floodwater levels, i.e., 0.08 m, 0.43 m, and 0.90 m were considered to represent ankle, knee, and waist heights, respectively. …”
Get full text
Get full text

Changes in expression of Kv7.5 and Kv7.2 channels in dorsal root ganglion neurons in the streptozotocin rat model of painful diabetic neuropathy by Laiche, Djouhri

“…We found 35 days post-STZ: (1) a significant decrease in Kv7.5-immunoreactivity in small (<30 μm) DRG neurons (both IB4 positive and IB4 negative) and medium-sized (30−40 μm) neurons, and (2) a significant increase in Kv7.2-immunoreactivity in small (<30 μm) neurons, and a non-significant increase in medium/large neurons. …”
Get full text
Get full text
Get full text

Inter-annual variability and distribution of aerosols during winters and aerosol optical thickness over Northeastern Pakistan by Shahid, M. Z.

“…Average over winters from 2007–2015, over the for four mega cities, Islamabad, Lahore, Faisalabad and Multan, the concentrations of sulfate were 5.06, 14.09, 14.29, 16.22 µg m−3, BC, were 1.5, 4.69, 4.46 4.52 µg m−3 and OC, were, 5.85, 17.32, 16.99 and 17.29 µg m−3, respectively. …”
Get full text
Get full text

Optimal Proactive Resource Allocation at the Extreme Edge by El Khatib, Rawan F.

Get full text
Get full text

Preliminary investigation of elevated collagen and blood-clotting markers as potential noninvasive biomarkers for small cell lung cancer by Thorlacius-Ussing, Jeppe

“…However, we observed a decrease in the degradation of type I collagen following chemotherapy. …”
Get full text
Get full text

Pilot-scale petroleum refinery wastewaters treatment systems: performance and microbial communities' analysis by Karray, Fatma

“…Decreasing HRT to 5 and 2.5 days led to a decrease in the efficiency of the process and a decrease in biomass concentration was also observed (<1000 mg/l). …”
Get full text
Get full text

Modelling the asymmetric responses of price level to oil price changes in Qatar by Mrabet, Zouhair

“…To achieve that, we proceed by employing a nonlinear autoregressive distributed lag (ARDL) approach on data during the period 1990Q1-2014Q4. The estimation results show evidences of an incomplete and asymmetric influence of oil price on price level in the long term. …”
Get full text
Get full text

Climatology and variability of wind speeds along the southwest coast of India derived from Climate Forecast System Reanalysis winds by Abdulla, Cheriyeri Poyil

“…The study reveals significant decreasing trends in annual mean wind speeds, of the order of −2.0 to −2.5 cm·s−1·year−1, for the period 1979–2019. …”
Get full text
Get full text
Get full text

Evacuated tube heat pipe solar collector for Encontech engine-driven reverse osmosis solar desalination by Takalkar, Gorakshnath

“…The maximum energetic efficiency of 52.5% is obtained for h vacuum (1 W/m2 K). Obtained results further demonstrate that the energetic and exergetic performances of the ETHPSC are higher at T i = 50°C. …”
Get full text
Get full text

Low levels of Vitamin D during pregnancy associated with gestational diabetes mellitus and low birth weight: results from the MAASTHI birth cohort by Deepa, R.

“…Furthermore, causal mediation analysis showed that a decrease in one unit of Vitamin D is associated with a decrease of 0.015 units of fasting blood sugar (FBS) and 0.019 units of postprandial blood sugar (PPBS) as it flows through the mediator variable insulin resistance. …”
Get full text
Get full text

Numerical investigation of rotating stall in centrifugal compressor with vaned and vaneless diffuser by Halawa, Taher

Get full text
Get full text
Get full text

Reinfections in COVID-19 Patients: Impact of Virus Genetic Variability and Host Immunity by Fakhroo, Aisha

“…This increase was associated with the emergence and spread of the new SARS-CoV-2 variants of concern (VOCs), such as the U.K. (B1.1.7), South Africa (B1.351), Brazil (P1), and Indian (B1.617.2) strains. …”
Get full text
Get full text

Effects of combined calcium hypochlorite and chlorine dioxide on drinking water quality in Qatar and disinfection by-products formation by Mohamed, Elsamoul H.

“…Seven water samples were collected from the Ras Laffan-Q Power desalination plant outlet in amber bottles having a chlorine dioxide concentration of 0.3 mg/L in 1 liter. …”
Get full text
Get full text

Influence of the heteroatom on the optoelectronic properties and transistor performance of soluble thiophene-, selenophene- and tellurophene-vinylene copolymers by Al-Hashimi, Mohammed

“…The optical band gap of the polymers is shown to systematically decrease as the size of the heteroatom is increased, mainly as a result of a stabilization of the LUMO energy, resulting in a small band gap of 1.4 eV for P3TeV. …”
Get full text
Get full text

Effect of left atrial ligation-driven altered inflow hemodynamics on embryonic heart development: clues for prenatal progression of hypoplastic left heart syndrome. by Salman, Huseyin Enes

“…Congenital heart defects (CHDs) are abnormalities in the heart structure present at birth. One important condition is hypoplastic left heart syndrome (HLHS) where severely underdeveloped left ventricle (LV) cannot support systemic circulation. …”
Get full text
Get full text

Asymmetric effects of oil price shocks on the demand for money in Algeria by Amirouche, Chelghoum

“…This paper investigates the symmetric and asymmetric effects of real oil prices on real money demand in Algeria over the period 1999:Q1–2020:Q1. Using a linear autoregressive distributed lag model (ARDL), and a nonlinear autoregressive distributed lag model (NARDL), we find no evidence of a long-term relationship among the variables. …”
Get full text
Get full text
Get full text