يعرض 101 - 120 نتائج من 1,793 نتيجة بحث عن '(( 10 ((we decrease) OR (((a decrease) OR (mean decrease)))) ) OR ( 10 i decrease ))*', وقت الاستعلام: 0.27s تنقيح النتائج
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    Signaling pathways activated by PACAP in MCF-7 breast cancer cells حسب Zibara, Kazem

    منشور في 2018
    "…In conclusion, we demonstrated that PACAP signaling in MCF-7 cells follows the Src/Raf/ERK and PI3K/AKT pathways and is VPAC1 dependent in a ROS dependent manner, whereas it follows PLC and PKA/cAMP pathways and is VPAC2 dependent through p38 MAP kinase activation involving calcium.…"
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  14. 114

    Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart حسب Akhtar, Saghir

    منشور في 2022
    "…Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH2, -COOH and -OH) on cardiac function in mammalian hearts following ischemia-reperfusion (I/R) injury, and (b) determined if any PAMAM-induced cardiotoxicity could be mitigated by Angiotensin-(1-7) (Ang-(1-7), a cardioprotective agent. …"
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