S3 File - by Changlong Yang (8392152)

“…</p><p>Results</p><p>Our analysis provided compelling evidence for the causal association of higher genetically predicted eosinophil cell count (EOS, odds ratio [OR], 0.8639; 95% confidence interval [CI] 0.7922–0.9421) and red cell distribution width (RDW, OR, 0.9981; 95% CI, 0.9972–0.9989) levels with a decreased risk of CRC. Additionally, we found suggestive evidence indicating that higher levels of total cholesterol (TC, OR, 1.0022; 95% CI, 1.0002–1.0042) may increase the risk of CRC. …”

S2 File - by Changlong Yang (8392152)

“…</p><p>Results</p><p>Our analysis provided compelling evidence for the causal association of higher genetically predicted eosinophil cell count (EOS, odds ratio [OR], 0.8639; 95% confidence interval [CI] 0.7922–0.9421) and red cell distribution width (RDW, OR, 0.9981; 95% CI, 0.9972–0.9989) levels with a decreased risk of CRC. Additionally, we found suggestive evidence indicating that higher levels of total cholesterol (TC, OR, 1.0022; 95% CI, 1.0002–1.0042) may increase the risk of CRC. …”

Data_Sheet_1_Enhancing pathogen description and antibiotic regimen selection in community-acquired pneumonia through RT-qPCR assays.doc by Na Zhao (112953)

“…It showed potential in optimizing antimicrobial prescriptions by allowing for de-escalation in 18.30% (95/518) of patients, among which reducing the number of excessive antibiotics mainly comprised decreasing the use of 2nd or 3rd generation cephalosporins (5.79%, 30/518) and β-lactamase inhibitor combinations.…”

Data_Sheet_1_Modeling Current and Future Potential Distributions of Milkweeds and the Monarch Butterfly in Idaho.docx by Leona K. Svancara (6705392)

“…Models project slight decreases (−1,318 km²) in potential suitable habitat for showy milkweed and significant increases (+5,830 km²) for swamp milkweed. …”

S4 File - by Changlong Yang (8392152)

“…</p><p>Results</p><p>Our analysis provided compelling evidence for the causal association of higher genetically predicted eosinophil cell count (EOS, odds ratio [OR], 0.8639; 95% confidence interval [CI] 0.7922–0.9421) and red cell distribution width (RDW, OR, 0.9981; 95% CI, 0.9972–0.9989) levels with a decreased risk of CRC. Additionally, we found suggestive evidence indicating that higher levels of total cholesterol (TC, OR, 1.0022; 95% CI, 1.0002–1.0042) may increase the risk of CRC. …”

TRAIL attenuates RANKL-mediated osteoblastic signalling in vascular cell mono-culture and co-culture models by Emma Harper (4597789)

“…<div><p>Background and objectives</p><p>Vascular calcification (VC) is a major risk factor for elevated cardiovascular morbidity/mortality. …”

Data_Sheet_1_Investigation of Electrically Evoked Auditory Brainstem Responses to Multi-Pulse Stimulation of High Frequency in Cochlear Implant Users.ZIP by Ali Saeedi (4815120)

“…Multi-pulses with a high burst rate of 10,000 pps were assembled from pulses of 45-μs phase duration. …”

Signature of Aberrant DNA Methylation in <i>MYC</i>-Induced T cell Lymphomas by Rene Opavsky (32415)

“…Methylation data from the analysis of three sets of EGFP-positive and EGFP-negative thymocytes isolated from 21-d-old <i>EμSR-tTA;Teto-MYC;Teto-Cre;Rosa26LOXP^EGFP</i> mice are also shown (see text and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030167#pgen-0030167-g002" target="_blank">Figure 2</a>).…”

Data_seed_preference_Vertebrate_Biology.xlsx by František Sedláček (18855925)

“…In all GLMMs (7 tree seeds), the testing day was a significant variable. In seeds of spruce, pine and lime the clear positive selection at the beginning decreased during the test, in hornbeam and oak the selection was the opposite. …”

Data_seed_preference_Vertebrate_Biology.xlsx by František Sedláček (18855925)

“…In all GLMMs (7 tree seeds), the testing day was a significant variable. In seeds of spruce, pine and lime the clear positive selection at the beginning decreased during the test, in hornbeam and oak the selection was the opposite. …”

Effects of charge neutralizing alanine mutations mapped to the kinesin-1 structure. by Barry J. Grant (19471)

“…(B) The results of experimental mutagenesis on K_mMT for microtubule-activated ATPase activity (sites in yellow increase, whilst those in blue decrease K_mMT); see Woehlke et al.<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001207#pbio.1001207-Woehlke1" target="_blank">[22]</a> for details.…”

Random forest method for analysis of remote sensing inversion of aboveground biomass and grazing intensity of grasslands in Inner Mongolia, China by Shuai Wang (109515)

“…The spatial distribution of AGB in Inner Mongolia grasslands showed a tendency of decreasing from southeast to northwest, with an increasing trend in the last 10 years. …”

Table_1_Temporal trends in cardiovascular health among Chinese urban children and adolescents, 2004–2019 pre-pandemic COVID-19.docx by Pei Xiao (466657)

“…Notably, the proportion of ideal body mass index (2004, 77.5%; 2019, 59.7%) and blood pressure (2004, 73.6%; 2019, 67.3%) continuously decreased from 2004 to 2019. …”

Segments of the original recordings from the same animal as Fig 2. by Sean J. Reed (724381)

Small-world parameters of networks. by Zhiliang Liu (525470)

The gut microbiota undergoes dynamic changes during host aging. by Francisco Daniel Davila Aleman (7042712)

 'Plan-B':  Impact of changes in the global funding landscape for Hepatitis B clinical and research programmes by marion delphin (13249479)

“…<p dir="ltr"><b>Introduction:</b> Major cuts have been made to the global funding landscape since the beginning of 2025, including pausing or cancellation of existing grants, and cuts to specific organisations providing health interventions including PEPFAR and USAID. </p><p dir="ltr">We set out to explore the perceived current and future impact on funding for hepatitis B virus (HBV) programmes. …”

Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis by Shaogui Wang (310181)

“…As a result, cerulein decreased the number of lysosomes resulting in insufficient autophagy in mouse pancreas. …”

Proteins reduced on chromatin in the absence of APC, but with unchanged dynamics of chromatin association. by Dina Dikovskaya (158354)

“…<p>Data were processed as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0038102#pone-0038102-t002" target="_blank">table 2</a>. …”

Epoxygenase <i>Cyp2c44 </i>regulates hepatic lipid metabolism and insulin signaling by controlling FATP2 localization and activation of the DAG/PKCδ axis by Kakali Ghoshal (4639600)