αENaC and S protein compete for furin-mediated cleavage in a cellular system. by Germán Ricardo Magaña-Ávila (18446799)

The Quest for the Ideal Base: Rational Design of a Nickel Precatalyst Enables Mild, Homogeneous C–N Cross-Coupling by Richard Y. Liu (1335162)

Comparison of mycobacterial growth inhibitory effects of plumbagin, lawsone, and rifampicin. by Apurba Sarkar (8399571)

Injury-induced cold sensitization in <i>Drosophila</i> larvae involves behavioral shifts that require the TRP channel Brv1 by Heather N. Turner (6157268)

“…Under baseline, non-injured conditions larvae primarily produce a CT response to an acute cold (10°C) stimulus, however, we show that cold-evoked responses shift following tissue damage: CT responses decrease, US responses increase and some larvae exhibit a lateral body roll (BR) that is typically only observed in response to high temperature and noxious mechanical stimuli. …”

Schematic representation of possible results using the dual-probe method (using real-time readout as an example). by Nidhi Nandu (5145473)

Nuclear Membrane-Targeted Gold Nanoparticles Inhibit Cancer Cell Migration and Invasion by Moustafa R. K. Ali (1306710)

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon by Josephine M. Reynaud (732822)

Nuclear Membrane-Targeted Gold Nanoparticles Inhibit Cancer Cell Migration and Invasion by Moustafa R. K. Ali (1306710)

Osteogenic differentiation of mesenchymal stem cells is enhanced in a 45S5-supplemented β-TCP composite scaffold: an <i>in-vitro</i> comparison of Vitoss and Vitoss BA - Fig 4 by Fabian Westhauser (5314436)

Correlates of osteogenic differentiation. by Fabian Westhauser (5314436)

Immunofluorescence of the sst2A receptor in coronal sections through the rat neocortical wall between E14 and P5. by Virginia Le Verche (372926)

“…CP/MZ, cortical plate/marginal zone; CP, cortical plate; MZ, marginal zone; VZ, ventricular zone; I–VI, cortical layers I to VI; WM, white matter. Scale bars: A–A″, B–B″, 50 µm; C–C″, D–D″, E–E″, 100 µm; A″′–E″′,10 µm.…”

Effect of anti-<i>Leishmania</i> drugs added to a sugar diet on the longevity of <i>Lu. longipalpis</i> females. by Tainá Neves Ferreira (21601579)

Functional analyses of <i>POLG1</i> variants and mutations. by Bhupendra Singh (343330)

Biophysical Characterization Platform Informs Protein Scaffold Evolvability by Alexander W. Golinski (6372443)

“…Our results support this connection between developability and evolvability by demonstrating a relationship between protein production in the soluble fraction of <i>Escherichia coli</i> and the ability to evolve binding function upon mutation. We further explain the necessity for initial developability by observing a decrease in proteolytic stability of protein mutants that possess binding functionality over nonfunctional mutants. …”

Despair by age UK, UKHLS, 2009–2021. by David G. Blanchflower (8011427)

pone.0327858.t001 - by David G. Blanchflower (8011427)

pone.0327858.t002 - by David G. Blanchflower (8011427)

US Suicide Rate. by David G. Blanchflower (8011427)

Despair in the USA, 1993-2024. by David G. Blanchflower (8011427)

Despair by age, BRFSS. by David G. Blanchflower (8011427)