Supplementary file 1_Impact of iron chelation therapy on mitochondrial function, vascular integrity and inflammation in transfusion-dependent myelodysplastic syndromes.docx by Regina García-Delgado (22589807)

“…</p>Results<p>Chelation therapy was associated with a ~55% decrease in serum ferritin and robust redox recovery: leukocyte H₂O₂ and superoxide decreased ~3.8-fold and ~3.2-fold, respectively (both p<0.0001), intracellular glutathione increased ~3.3-fold (p<0.0001), and mitochondrial membrane potential rose ~2.6-fold (p<0.0001). …”

Kidney-specific <i>Memo1</i> kKO mice displayed elevated magnesemia and renal magnesium channel transcription. by Matthias B. Moor (5491208)

“…In the kidney <i>Trpm6</i> tended to increase and <i>Trpm7</i> significantly increased in <i>Memo1</i> kKO, whereas <i>Egf</i> and <i>Egfr</i> transcription were unchanged. p < 0.05 (t-test); ns, not significant. n = 1 per genotype (A) but representative of several experiments; sera or spot urines of 16 male mice age 8 weeks pooled to 4 independent samples per genotype (B-D); 5 per genotype (E-F).…”

Table_4_Efficacy of Chinese Herbal Formula Sini Zuojin Decoction in Treating Gastroesophageal Reflux Disease: Clinical Evidence and Potential Mechanisms.doc by Shaowei Li (252115)

“…</p>Results<p>Thirteen articles were eventually included, covering a total of 966 patients. Meta-analysis indicated that: ① the SNZJD plus traditional stomach medicines (SPTSM) group was more effective than the traditional stomach medicines (TSM) group (RR = 1.16, 95% CI [1.04, 1.29], P = 0.009); ② the experimental group with SNZJD was significantly better than TSM controls in improving heartburn, substernal chest pain, acid regurgitation, and food regurgitation symptoms (P < 0.0001); ③ SPTSM could significantly decrease total symptom scores with substantial effectiveness (P < 0.00001). …”

Table1_Plasma alpha-trypsin inhibitor heavy chain 4 as an age-specific biomarker in the diagnosis and treatment of major depressive disorder.docx by Ping He (33281)

“…There was significant decrease in plasma levels of ITIH4 between before and after antidepressive treatment in adult MDD patients, but not in adolescent MDD patients (5). …”

Data_Sheet_1_The benefits of flushing for mitigating Legionella spp. in non-chlorinated building plumbing systems.pdf by Charuka S. Meegoda (14819461)

“…Even after all outlets returned to active water demand, flushed shower outlets continued to have lower quantities of Legionella compared to non-flushed outlets for several days, but the decrease was of little practical benefit (<0.5 log₁₀[copies/L]). …”

Table 1_High-dose medium-term HMB supplementation did not trigger body composition changes in trained and untrained males under usual conditions or high-intensity functional exerci... by Krzysztof Durkalec-Michalski (4691311)

“…Nevertheless, there was an impact (p < 0.05) from training status (but not HMB/PLA) on FM (kg; slight increases in UTR) and TBW (slight decreases in UTR).</p>Discussion<p>The individually adjusted high HMB dose did not change body mass and composition in trained or untrained individuals during a three-week exclusive supplementation or three-week supplementation in combination with additional HIFT stimuli. …”

Data_Sheet_1_Hydroxyurea Scavenges Free Radicals and Induces the Expression of Antioxidant Genes in Human Cell Cultures Treated With Hemin.DOCX by Sânzio Silva Santana (9136571)

“…Significant increases in expression were observed in genes with kinase activity: protein kinase C beta (PRKCB), zeta (PRKCZ) and phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta (PIK3C2B). HU also induced a significant increase in expression of the gene p62/sequestosome (p62/SQSTM1) and a significant decrease in the expression of the transcriptional factor BACH1 in HUVECs. …”

DataSheet_1_Relative contribution of the presence of an estuarine dam and land reclamation to sediment dynamics of the Nakdong Estuary.docx by Jongwi Chang (15429521)

“…The increase of velocity and SSC for Case 2 resulted from the removal of the estuarine dam, which changed both the tidal properties (tidal amplitude was reduced by about 40 cm) and estuarine circulation (factor of 5 reductions in the vertical salinity gradient), while the decrease for Case 3 was induced by the reduction in sediment accommodation space (15% of water volume) without a change in the circulation. …”

Supplementary file 2_Impact of iron chelation therapy on mitochondrial function, vascular integrity and inflammation in transfusion-dependent myelodysplastic syndromes.docx by Regina García-Delgado (22589807)

“…</p>Results<p>Chelation therapy was associated with a ~55% decrease in serum ferritin and robust redox recovery: leukocyte H₂O₂ and superoxide decreased ~3.8-fold and ~3.2-fold, respectively (both p<0.0001), intracellular glutathione increased ~3.3-fold (p<0.0001), and mitochondrial membrane potential rose ~2.6-fold (p<0.0001). …”

Table_1_Efficacy of Chinese Herbal Formula Sini Zuojin Decoction in Treating Gastroesophageal Reflux Disease: Clinical Evidence and Potential Mechanisms.xlsx by Shaowei Li (252115)

“…</p>Results<p>Thirteen articles were eventually included, covering a total of 966 patients. Meta-analysis indicated that: ① the SNZJD plus traditional stomach medicines (SPTSM) group was more effective than the traditional stomach medicines (TSM) group (RR = 1.16, 95% CI [1.04, 1.29], P = 0.009); ② the experimental group with SNZJD was significantly better than TSM controls in improving heartburn, substernal chest pain, acid regurgitation, and food regurgitation symptoms (P < 0.0001); ③ SPTSM could significantly decrease total symptom scores with substantial effectiveness (P < 0.00001). …”

Table_1_Moderate Dietary Protein Restriction Optimized Gut Microbiota and Mucosal Barrier in Growing Pig Model.DOCX by Xiyue Chen (5527046)

“…Ileal abundances of Streptococcaceae and Enterobacteriaceae decreased respectively, while beneficial Lactobacillaceae, Clostridiaceae_1, Actinomycetaceae, and Micrococcaceae increased their proportions with a protein reduction of 3 percentage points. …”

Design of Recyclable Adsorbent for Water Pollutants Based on Chitosan-Coated Carboxymethyl Cellulose-Calcium Alginate Wrapped Iron Oxide-Copper Oxide Composite Beads by Nujud Maslamani (19825632)

“…However, increasing the beads dose led to a decrease in the Ag(I) ion adsorption. Further, the waste beads after Ag(I) adsorption were treated with reducing agent to form beads supported Ag nanoparticles (Ag/Cs@CA-CMC/Fe₂O₃-CuO) and used as effective catalyst for reducing 4-nitrophenol in the presence of NaBH₄ as a reducing agent. …”

Image_1_Efficacy of Chinese Herbal Formula Sini Zuojin Decoction in Treating Gastroesophageal Reflux Disease: Clinical Evidence and Potential Mechanisms.pdf by Shaowei Li (252115)

“…</p>Results<p>Thirteen articles were eventually included, covering a total of 966 patients. Meta-analysis indicated that: ① the SNZJD plus traditional stomach medicines (SPTSM) group was more effective than the traditional stomach medicines (TSM) group (RR = 1.16, 95% CI [1.04, 1.29], P = 0.009); ② the experimental group with SNZJD was significantly better than TSM controls in improving heartburn, substernal chest pain, acid regurgitation, and food regurgitation symptoms (P < 0.0001); ③ SPTSM could significantly decrease total symptom scores with substantial effectiveness (P < 0.00001). …”

Sex hormone stimulation of CRISPR-modified HepG2 cells alters alpha-1 antitrypsin production by Emma Leacy (11872358)

“…</p><p dir="ltr"><b>Results:</b> Both hormones significantly reduced intracellular AAT (Figure 1A), even at low concentrations. There was also a dose-dependent decrease in AAT release, particularly in oestrogen-treated cells (Figure 1C). …”

Levels of degron-tagged AIR-2 and kinase-dead AIR-2 transgenes in worm strains. by Nikita S. Divekar (5714540)

“…Comparison of the endogenously-expressed bands shows a decrease upon auxin addition, though it is worth noting that these samples were generated from whole worms, while AIR-2 was only depleted in the germ line. …”

Furosemide Cocrystals with Pyridines: An Interesting Case of Color Cocrystal Polymorphism by Ekta Sangtani (1472398)

“…Crystallization from ethanol, isopropanol, ethanol–water (v/v, 1/1) mixture, and acetonitrile yielded pale yellow (form <b>1</b>I, thin needles) and orange (form <b>1</b>II, blocks) cocrystals concomitantly. …”

Data_Sheet_1_Effects of intrinsic tannins on proteolysis dynamics, protease activity, and metabolome during sainfoin ensiling.docx by Rong Zheng Huang (13263753)

“…<p>Condensed tannins (CT) from sainfoin have a high capacity to inhibit proteolysis. A previous study reported that CT from sainfoin can inhibit lactic acid bacteria activity and decrease ammonium-nitrogen (N) content during sainfoin ensiling; however, no study has focused on the metabolome of ensiled sainfoin. …”

Table2_Plasma alpha-trypsin inhibitor heavy chain 4 as an age-specific biomarker in the diagnosis and treatment of major depressive disorder.xlsx by Ping He (33281)

“…There was significant decrease in plasma levels of ITIH4 between before and after antidepressive treatment in adult MDD patients, but not in adolescent MDD patients (5). …”

Table 2_High-dose medium-term HMB supplementation did not trigger body composition changes in trained and untrained males under usual conditions or high-intensity functional exerci... by Krzysztof Durkalec-Michalski (4691311)

“…Nevertheless, there was an impact (p < 0.05) from training status (but not HMB/PLA) on FM (kg; slight increases in UTR) and TBW (slight decreases in UTR).</p>Discussion<p>The individually adjusted high HMB dose did not change body mass and composition in trained or untrained individuals during a three-week exclusive supplementation or three-week supplementation in combination with additional HIFT stimuli. …”

Table_1_Effects of intrinsic tannins on proteolysis dynamics, protease activity, and metabolome during sainfoin ensiling.XLSX by Rong Zheng Huang (13263753)

“…<p>Condensed tannins (CT) from sainfoin have a high capacity to inhibit proteolysis. A previous study reported that CT from sainfoin can inhibit lactic acid bacteria activity and decrease ammonium-nitrogen (N) content during sainfoin ensiling; however, no study has focused on the metabolome of ensiled sainfoin. …”