Alcohol and breast cancer risk: Middle-aged women’s logic and recommendations for reducing consumption in Australia by Samantha B. Meyer (555077)

Host population bottlenecks decrease microbiome diversity. by Michael Ørsted (5926028)

Systemic metabolic switch and glycogen breakdown are required for effective resistance to <i>Streptococcus pneumoniae</i>. by Adam Bajgar (730380)

Tukey HSD results showing difference in mean levels of Period for Bos taurus. by Katie Manning (832899)

Host survival and pathogen load during <i>Listeria monocytogenes</i> infection. by Adam Bajgar (730380)

Extracellular adenosine modulates host-pathogen interactions through regulation of systemic metabolism during immune response in <i>Drosophila</i> by Adam Bajgar (730380)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

Adjusted means and 95% confidence interval of blood pressure change from baseline to the follow-up in different general or abdominal obesity status change groups. by Yi-de Yang (6755798)

Influence of stabilized MetA protein on the <i>E.coli</i> WE strain growth under stressful conditions. by Elena A. Mordukhova (646403)

Average number of cumulative new HIV infections and mean number of averted HIV infections among African American women over 20-year period by scenario. by Joëlla W. Adams (2192254)

Linear decrease of delta power (1.1–5.0 Hz) across the first three sleep cycles in the cortical, hippocampal and scalp recordings. by Fabio Moroni (34208)

Mean (SD) scores of infrahumanization and dehumanization in Study 1. by Thomas Davies (4342306)

Mean (± SE) percent survival of female western mosquitofish in the presence of a predator based on stage of pregnancy and availability of refuge. by Clinton T. Laidlaw (653664)

Correlation analysis of the change of executive functions with the decrease of mobile phone addiction index and the increase of mindfulness level. by Jizhao Li (5856650)

Antibodies used for flow cytometry experiments. by Joseph Rabin (7399436)

“…RA was devoid of serious side effects, and within 24 hours from the start of infusion was associated with increased oxygen saturation (93.8 ± 0.58 vs 96.6 ± 1.08%, P<0.05), decreased D-dimer (754 ± 17 vs 518 ± 98 ng/ml, P<0.05), and a trend toward decreased CRP (3.80 ± 1.40 vs 1.98 ± 0.74 mg/dL, P = 0.075). …”

Subject flow diagram. by Joseph Rabin (7399436)

“…RA was devoid of serious side effects, and within 24 hours from the start of infusion was associated with increased oxygen saturation (93.8 ± 0.58 vs 96.6 ± 1.08%, P<0.05), decreased D-dimer (754 ± 17 vs 518 ± 98 ng/ml, P<0.05), and a trend toward decreased CRP (3.80 ± 1.40 vs 1.98 ± 0.74 mg/dL, P = 0.075). …”

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…Moreover, the compound dose-dependently decreases β-site amyloid precursor protein cleaving enzyme (BACE-1) activity with EC₅₀ value in micromolar range. …”

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…Moreover, the compound dose-dependently decreases β-site amyloid precursor protein cleaving enzyme (BACE-1) activity with EC₅₀ value in micromolar range. …”

Distribution of mean seasonal rainfall in the study area. by Menbere Sahilu (18195856)

Subjects: