Kidney-Specific Reduction of Oxidative Phosphorylation Genes Derived from Spontaneously Hypertensive Rat by Jason A. Collett (787818)

“…We hypothesize that renal Mt-genes derived from female spontaneously hypertensive rats (SHR) that exhibit hypertension have reduced expression specific to kidney cortex. After breeding a female Okamoto-Aoki SHR (SAP = 188mmHg) with Brown Norway (BN) males (SAP = 100 and 104 mmHg), hypertensive female progeny were backcrossed with founder BN for 5 consecutive generations in order to maintain the SHR mitochondrial genome in offspring that contain over increasing BN nuclear genome. …”

Table 1_Global, regional, and national burden of sudden infant death syndrome and the impact of COVID-19: a trend and health inequality analysis based on the global burden of disea... by Xinkuo Zheng (21785660)

“…</p>Results<p>In 2021, the ASDR of SIDS accounted for 44.16 (95% UI: 25.70–59.26) per 100,000 population globally, which was a 58.97% decrease from 1990. …”

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β₁-Adrenoceptor Identifies an Intramembrane Na⁺ Ion that Stabilises the Ligand-Free Receptor by Jennifer L. Miller-Gallacher (541986)

“…We have determined the structure of an ultra-thermostable β₁AR mutant bound to the weak partial agonist cyanopindolol to 2.1 Å resolution. …”

(goes with Fig 5). by Patrick A. Carroll (11586792)

“…(<b>D</b>) IHC analysis of WT versus MLX^KO testis and epididymis stained for the proliferation marker Ki-67 (100×, scale bar = 400 uM). Asterisks marks acellular tubule with decreased Ki-67. …”

Image_1_Subpopulation treatment effect pattern plot analysis: a prognostic model for distant recurrence-free survival to estimate delayed adjuvant chemotherapy initiation effect in... by Zaida Morante (9292533)

“…Kaplan-Meier plots showed that in the discovery set, patients with TTC>30 days experienced a 17.5% decrease in 10-year DRFS rate (95%CI=6.7-28.3), and the impact was more remarkable in patients who belong to the high-risk subgroup (53.3% decrease in 10 years-DRFS rate). …”

Long-term trends in incidence and risk factors for ischaemic stroke subtypes: Prospective population study of the South London Stroke Register by Hatem A. Wafa (5823872)

“…Between 2000–2003 and 2012–2015, the age-adjusted incidence of IS decreased by 43% from 137.3 to 78.4/100,000/year (incidence rate ratio [IRR] 0.57, 95% CI 0.5–0.64). …”

Addressing Imbalanced Classification Problems in Drug Discovery and Development Using Random Forest, Support Vector Machine, AutoGluon-Tabular, and H2O AutoML by Ayush Garg (21090944)

Table1_Effectiveness and safety of tenofovir amibufenamide and its comparison with tenofovir alafenamide in patients with chronic hepatitis B: results from a retrospective real-wor... by Lanqing Li (11505488)

“…The ratios of alanine transaminase (ALT) normalization were 89% (25/28) in the treatment-naive group and 71% (10/14) in the treatment-experienced group (p = 0.306). …”

Table 2_Global, regional, and national burden of intracerebral hemorrhage and attributable risk factors in youths and young adults, 1990–2021: a statistical analysis of incidence,... by Bing Wu (172312)

“…The incidence rate declined from 11.31 (95% UI, 8.56, 14.27) per 100,000 individuals in 1990 to 8.30 (95% UI, 6.46, 10.19) per 100,000 individuals in 2021, an overall decrease of −26.62% (95% UI, −30.85 to −22.24). …”

Table 1_Global, regional, and national burden of intracerebral hemorrhage and attributable risk factors in youths and young adults, 1990–2021: a statistical analysis of incidence,... by Bing Wu (172312)

“…The incidence rate declined from 11.31 (95% UI, 8.56, 14.27) per 100,000 individuals in 1990 to 8.30 (95% UI, 6.46, 10.19) per 100,000 individuals in 2021, an overall decrease of −26.62% (95% UI, −30.85 to −22.24). …”

Table 1_The burden of gastric cancer attributed to high salt intake and predictions through the year 2042: a cross-national comparative analysis of China, Japan, and South Korea.do... by Wei Liu (20030)

“…Globally, ASMR decreased from 1.74 per 100,000 in 1990 to 0.89 per 100,000 in 2021 (EAPC = −2.26). …”

Patterning in Birthweight in India: Analysis of Maternal Recall and Health Card Data by Malavika A. Subramanyam (104709)

“…Children were less likely to be born with low birthweight if they had mothers with over 12 years of education compared to 1–5 years of education with relative risk (RR) of 0.79 (95% confidence interval [CI]: 0.52, 1.2) in the card sample and 0.70 (95% CI: 0.59, 0.84) in the recall sample. A 100 gram difference in a child's birthweight was associated with a decreased likelihood of underweight in both the card (RR: 0.95; 95% CI: 0.94, 0.96) and recall (RR: 0.96; 95% CI: 0.96, 0.97) samples.…”

Composition of binding sites for the top-20 valid ligands. by Nickolay A. Khazanov (488317)

“…Due to rounding, rows may occasionally sum to a value other than 100%.</p>…”

Devices for BART assays and different formats of BART data output. by Olga A. Gandelman (236217)

“…(F) Corresponding images of LAMP-BART reactions taken at 10 (a), 21 (b), 24 (c), 25 (d), 26 (e) and 30 min (f): top row – ChAT DNA dilution series with the decreasing amount of template 1 ng, 100 pg, 10 pg, 1 pg (left to right); bottom row – no-template control.…”

Datasheet1_Deep vein thrombosis and pulmonary embolism: a prospective, observational study to evaluate diagnostic performance of the Tina-quant D-Dimer Gen.2 assay.docx by Thomas Bertsch (360246)

“…Background<p>D-Dimer testing is a diagnostic tool for exclusion of deep vein thrombosis (DVT) and pulmonary embolism (PE). …”

Digestive cell lysosomes as main targets for Ag accumulation and toxicity in marine mussels, <i>Mytilus galloprovincialis</i>, exposed to maltose-stabilised Ag nanoparticles of dif... by A. Jimeno-Romero (3691009)

“…<p>Bioavailability and toxicity of maltose-stabilised AgNPs of different sizes (20, 40 and 100 nm) in mussels were compared with bulk and aqueous forms of the metal through a two-tier experimental approach. …”

Synaptic plasticity and coincidence detection in the model Kenyon cell. by Luca A. Finelli (44577)

“…<p>(A) The SRDP rule was applied every 100 ms (large box over dashed time grid, see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000062#s4" target="_blank">Materials and Methods</a>). …”

Composition of binding sites for the top-20 invalid ligands. by Nickolay A. Khazanov (488317)

“…Due to rounding, rows may occasionally sum to a value other than 100%.</p>…”

Synergistic effect of nano-selenium and metformin on type 2 diabetic rat model: Diabetic complications alleviation through insulin sensitivity, oxidative mediators and inflammatory... by Shaymaa A. Abdulmalek (4025555)

“…Experimental animals either treated with mono-therapeutic-two doses Se-NPs (0.1 and 0.4 mg/kg) and/or MET (100 mg/kg) alone as well as the combined therapy resulted in a remarkable protective anti-diabetic effect illustrated by significant decreases in fasting blood glucose and insulin levels after 8 weeks treatment. …”

Data_Sheet_1_Agriculture by Irrigation Modifies Microbial Communities and Soil Functions Associated With Enhancing C Uptake of a Steppe Semi-Arid Soil in Northern Patagonia.PDF by Juan P. Frene (12227753)