S5 Data - by Christoph Anders (4068499)

Intracellular levels of HSPG core proteins, HS and HPSE are decreased in ER stressed MIN6 cells. by Sarita Dhounchak (10924448)

Rat tickling: A systematic review of applications, outcomes, and moderators by Megan R. LaFollette (3911140)

“…The most common method used for tickling was cycling through 15 seconds of tickling and 15 seconds of rest for 2 minutes for 3 to 5 days. Experiments with a control for tickling (N = 22) showed that tickling increases positive vocalization, approach behavior, decreases anxiety measures, improves handling, and in some cases decreases stress hormones. …”

2-MeSADP treatment decreases <i>in vivo</i> lesions induced by single vessel photothrombosis. by Wei Zheng (25452)

Genome wide decrease of DNA replication eye density at the midblastula transition of <i>Xenopus laevis</i> by Marie Platel (750508)

Caspase-1 activity did not account for decreased IL-1β in E6-positive cells. by Martina Niebler (440620)

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Supplementary Material for: Optimizing Cerebral Autoregulation May Decrease Neonatal Regional Hypoxic-Ischemic Brain Injury by Lee J.K. (3588656)

Decreased BK responsiveness of ERK activation is found only in PS-1 FAD mutant AD fibroblasts. by Graziella Mendonsa (374346)

A647D mutation decreases I_Na of WT and P1332L when co-expressed. by Jie Liu (15128)

Decreased MMP-9 protein expression induced by STIP1 knockdown is independent of common signaling pathways. by Hsin-Shih Wang (8802)

“…(B) Decreased MMP-9 protein expression induced by siRNA knockdown of STIP1 was unaffected by exposure either to the DNA methylation inhibitor 5-aza-2’-deoxycytidine (AZA; 10 μM) or the histone deacetylase inhibitor trichostatin A (TSA; 20 nM). …”

Down-regulation of GPER reverses the decreased expression of PCNA and cell morphology changes caused by G-1. by Fen Li (337013)

datasheet1_Allopregnanolone Decreases Evoked Dopamine Release Differently in Rats by Sex and Estrous Stage.docx by Ana Paula S. Dornellas (9983996)

“…Previous studies found that the endogenous GABAergic steroid (3α,5α)-3-hydroxy-5-pregnan-20-one (allopregnanolone) modulates dopamine levels in the nucleus accumbens and prefrontal cortex. …”

DataSheet_1_microRNA-144/451 decreases dendritic cell bioactivity via targeting interferon-regulatory factor 5 to limit DSS-induced colitis.pdf by Zhijie Lin (173992)

“…Thus, our results reveal a novel miR144/451-IRF5 pathway in DCs that protects experimental colitis. …”

Data Sheet 1_Probiotic Limosilactobacillus reuteri KUB-AC5 decreases urothelial cell invasion and enhances macrophage killing of uropathogenic Escherichia coli in vitro study.pdf by Arishabhas Tantibhadrasapa (13929639)

“…The human bladder epithelial cell line UM-UC-3 was used to assess the adhesion and pathogen-attachment inhibition properties of AC5 on UPEC.</p>Results and discussion<p>Our data showed that AC5 can attach to UM-UC-3 and decrease UPEC attachment in a dose-dependent manner. …”

Length-Dependent Convergence and Saturation Behavior of Electrochemical, Linear Optical, Quadratic Nonlinear Optical, and Cubic Nonlinear Optical Properties of Dipolar Alkynylruthe... by Bandar Babgi (2360545)

“…The syntheses of <i>trans</i>-[Ru{4,4′-CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>19</b>), <i>trans</i>-[Ru{4,4′,4′′-CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>20</b>), <i>trans</i>-[Ru{4,4′,4′′,4′′′-CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppe)₂] (<b>21</b>), <i>trans</i>-[Ru{4,4′,4′′,4′′′-CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>22</b>), <i>trans</i>-[Ru{4,4′,4′′,4′′′-CCC₆H₄CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>23</b>), and <i>trans</i>-[Ru{4,4′,4′′,4′′′,4′′′′-CCC₆H₄CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>24</b>) are reported, together with those of precursor alkynes, complexes with the donor−π-bridge−acceptor formulation that affords efficient quadratic and cubic NLO compounds; the identity of <b>19</b> was confirmed by a structural study. …”

Bee Venom for the Treatment of Parkinson Disease – A Randomized Controlled Clinical Trial by Andreas Hartmann (241073)

“…<div><p>In the present study, we examined the potential symptomatic and/or disease-modifying effects of monthly bee venom injections compared to placebo in moderatly affected Parkinson disease patients. We conducted a prospective, randomized double-blind study in 40 Parkinson disease patients at Hoehn & Yahr stages 1.5 to 3 who were either assigned to monthly bee venom injections or equivalent volumes of saline (treatment/placebo group: n = 20/20). …”