Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD) by Christina W. Agudelo (8415171)

“…Wild-type C57BL/6 mice were exposed to 6 months of second-hand smoke in a full-body chamber. Surfactant lipids were decreased by 60% in subjects with COPD. …”

The gut microbiome and metabolome in kidney transplant recipients with normal and moderately decreased kidney function by Yang Lan (1750390)

Effects of ROCK inhibitors H-1152 and Y-27632 on TNF-induced MLC phosphorylation, actin and CL5 reorganization and the fall in TEER. by Paul R. Clark (714064)

“…D) Effects of H-1152 and Y-27632 on the phase 1 and phase 2 TEER decreases induced by TNF. Starting at T₀, HDMEC plated on ECIS 96-well arrays received a 1 hour pre-treatment with vehicle (top panel, n = 4, 4) or with a ROCK inhibitor, either H-1152 (at 1 or 10 μM, middle panel, n = 6, 6) or Y-27632 (at 1 or 10 μM, bottom panel, n = 6, 6). …”

Nasal mucociliary clearance was decreased in <i>Ttll1</i>^−/− mice. by Toshiyuki Iwata (419270)

“…In the <i>Ttll1</i>^−/− mice, a larger amount of Evans blue persisted in the nasal cavity and a lesser amount was swallowed compared with that in the wild-type (WT) mice (mean ± SEM, n = 5, *P < 0.005 by two-tailed Student's t test).…”

Table_1_Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver.xlsx by Poonamjot Deol (773907)

“…In contrast, DMSO had no effect on the epoxide precursors or other oxylipins including those derived from arachidonic acid (C20:4n6) or eicosapentaenoic acid (EPA, C20:5n3). It also did not significantly affect the diol:epoxide ratio, suggesting a pathway distinct from, and potentially complementary to, soluble epoxide hydrolase inhibitors (sEHI). …”

The number of expected vaccinations decreases with the expected vaccination time, whereas the peak of infections increases. by Simon K. Schnyder (16632244)

Atmospheric Chlorine Wet Deposition in China: National Decreases but Localized Increases in Urban Agglomerations by Yue Xi (22336201)

Heart failure decreases adipocyte progenitors with impaired differentiation capacity toward mature adipocytes by Oto Inoue (21373982)

UNC-62 RNAi decreases expression of collagen genes and increases expression of intestinal genes. by Eric L. Van Nostrand (30730)

“…For 1699 genes with intestine-enriched expression <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-McGhee1" target="_blank">[23]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Pauli1" target="_blank">[33]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Spencer1" target="_blank">[34]</a> as well as the subset of 291 genes that also decrease expression with age <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Budovskaya1" target="_blank">[10]</a>, we determined the average mean-centered fold-change from triplicate RNA-seq experiments of <i>unc-62</i> RNAi as compared to controls. …”

miR-132 Knockdown Decreases Dendritic Spine Density <i>In Vivo</i>. by Bryan W. Luikart (351588)

Decreased Response to Acetylcholine during Aging of <i>Aplysia</i> Neuron R15 by Komolitdin Akhmedov (502827)

Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis by Zeynep Gök Sargın (4678663)

“…GEBOES grading system was also used. We demonstrated a profound loss (69.4%) of NEP expression in UC, whereas all healthy controls had NEP expression. …”

Novel agent DMAMCL suppresses osteosarcoma growth and decreases the stemness of osteosarcoma stem cell by Gen Ba (6440999)

Flow diagram of 10+10+30 intervention evaluation. by Bernard Appiah (5880953)

Muscle quality, but not muscle thickness, is decreased in different age groups of active older women by Pedro Lopez (4530202)

Lipolytic treatment decreased cellular neutral lipids and increased extracellular fatty acids and glycerol. by Caroline Louis (332423)

“…Cellular neutral lipids (corresponding to µmol of fatty acids in cellular neutral lipids) were expressed per mg of total cell protein (A). A significant decrease of cellular lipid contents was noted throughout the lipolytic process for the conditions with PCB-28 (<i>p</i> = 0.005) and the cocktail of PCBs (<i>p</i> = 0.029). …”

Desmosomal Cadherins Are Decreased in Explanted Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patient Hearts by Alexia Vite (462320)

“…Genetic studies have demonstrated the central role of desmosomal proteins in this disease, where 50% of patients harbor a mutation in a desmosmal gene. However, clinical diagnosis of the disease remains difficult and molecular mechanisms appears heterogeneous and poorly understood. …”

CsA reduces Flk1 protein expression and significantly decreases the percentages of Flk1+ cells. by Seung-Cheol Choi (686982)

Data_Sheet_1_Age-related decrease in motor contribution to multisensory reaction times in primary school children.PDF by Areej A. Alhamdan (13758430)

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”