Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol expo... حسب Frederik Abel (8452101)

"…Prior isoflurane exposure <i>in vitro</i> even increased protection (RIPC-EVs/control, apoptotic ratio: 0.79; p = 0.0035; Sham-EVs/control, apoptotic ratio:1.04) while propofol (50μM) abrogated protection by RIPC-EVs (RIPC-EVs/control, Apoptotic ratio: 1.01; Sham-EVs/control, apoptotic ratio: 0.94; p = 0.602). …"

Host population bottlenecks decrease microbiome diversity. حسب Michael Ørsted (5926028)

<i>In vitro</i> activity of aryl-thiazole derivatives against <i>Schistosoma mansoni</i> schistosomula and adult worms حسب Adriana S. A. Pereira (5900249)

"…Adult worms’ treatment with 50 μM NJ05, NJ07 or NJ05 + NJ07 showed decreased motility to 30–50% compared with controls. …"

Cell apoptosis of SW480 cells treated with 0.95 μM of Dox and 10 μM of AS-T9/U4_MH, AS-nonT9/U4_MH, Dox-loaded AS-T9/U4_MH, and Dox-loaded AS-nonT9/U4_MH at 48 h, and no treatment... حسب Kanpitcha Jiramitmongkon (6297269)

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study حسب Jemima Opare-Addo (14657955)

"…., nanodomains) characterized by their organization into distinct domains. We present evidence of nanodomains in trihexyl(tetradecyl)phosphonium chloride, [P₆₆₆₁₄][Cl], using single-molecule tracking (SMT) and the maximum entropy method (MEM) to analyze single-molecule trajectories. …"

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study حسب Jemima Opare-Addo (14657955)

"…., nanodomains) characterized by their organization into distinct domains. We present evidence of nanodomains in trihexyl(tetradecyl)phosphonium chloride, [P₆₆₆₁₄][Cl], using single-molecule tracking (SMT) and the maximum entropy method (MEM) to analyze single-molecule trajectories. …"

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study حسب Jemima Opare-Addo (14657955)

"…., nanodomains) characterized by their organization into distinct domains. We present evidence of nanodomains in trihexyl(tetradecyl)phosphonium chloride, [P₆₆₆₁₄][Cl], using single-molecule tracking (SMT) and the maximum entropy method (MEM) to analyze single-molecule trajectories. …"

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study حسب Jemima Opare-Addo (14657955)

"…., nanodomains) characterized by their organization into distinct domains. We present evidence of nanodomains in trihexyl(tetradecyl)phosphonium chloride, [P₆₆₆₁₄][Cl], using single-molecule tracking (SMT) and the maximum entropy method (MEM) to analyze single-molecule trajectories. …"

E₅₀ values. حسب Junxia Zhou (14381598)

K2 is active at a concentration of 3 μM and above. حسب Estelle Ifrid (10076719)

Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases حسب Xiao Li (107004)

"…CARM1 (coactivator-associated arginine methyltransferase 1), which belongs to type I PRMTs (protein arginine methyltransferases), is a potential therapeutic target for treatment of multiple cancers. In this study, we first identified several hit compounds against CARM1 by structure-based virtual screening (IC₅₀ = 35.51 ± 6.68 to 68.70 ± 8.12 μM) and then carried out chemical structural optimizations, leading to six compounds with significantly improved activities targeting CARM1 (IC₅₀ = 18 ± 2 to 107 ± 6 nM). …"

Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis حسب Chenlu Zhang (508309)

"…Evidence showed that intestinal FXR antagonism exhibited remarkable metabolic improvements in mice. Herein, we developed a series of betulinic acid derivatives as potent intestinal FXR antagonists, and <b>F6</b> was identified as the most potent one with an IC₅₀ at 2.1 μM. …"

Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis حسب Chenlu Zhang (508309)

"…Evidence showed that intestinal FXR antagonism exhibited remarkable metabolic improvements in mice. Herein, we developed a series of betulinic acid derivatives as potent intestinal FXR antagonists, and <b>F6</b> was identified as the most potent one with an IC₅₀ at 2.1 μM. …"

Optical Control of Insect Behavior and Receptors with Azobenzene-Bridged Fipronil and Imidacloprid حسب Wen Fu (2040040)

الموضوعات:

Supplementation of 10 μM C8-HSL in <i>lon</i> mutant cultures did not increase the level of oxalate biosynthetic protein to the wild-type level. حسب Eunhye Goo (212888)

Decreased glycosylated α-DG and laminin levels distal to the glial dome in <i>Large</i>^{<i>myd/myd</i>} mice. حسب Shigefumi Morioka (8893511)

Circulating numbers of T cell subsets in cells/μl prior to transplantation in relation to late kidney rejection. حسب Michiel G. H. Betjes (8407413)

NRH treatment dose-dependently decreased the number of surviving HepG3 cells. حسب Manoj Sonavane (5340581)

Image_1_Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3).JPEG حسب Vania A. Figueroa (8332773)

Table_1_Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3).DOCX حسب Vania A. Figueroa (8332773)