Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics by Nomikos, Michail

“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS by ELJILANY, ISLAM AHMED SAYED AHMED

“…The economic evaluation of the above practice demonstrated that the mean overall cost of peri-procedural warfarin management per patient was USD 3,260 (QAR 11,900), associated with an overall success rate of 0.752. …”
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Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus by Dimitrios, Patoulias

“…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …”
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Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review by Sunji, Nadine

“…Post-COVID-19 onset, 1.7 % of patients tested positive for any STI compared with 1.1 % pre-COVID-19 onset (OR: 1.5, 95%CI: 0.8–2.7). Close to 90 % of all positive diagnoses were among MSM. …”
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Solar hydrogen production via a samarium oxide-based thermochemical water splitting cycle by Bhosale, Rahul

“…The computational thermodynamic analysis of a samarium oxide-based two-step solar thermochemical water splitting cycle is reported. …”
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Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes by Kwon, Taeoh

“…However, in the temperate biome where atmospheric N deposition rates are relatively high, the 12-month mass loss of Green and Rooibos teas decreased significantly with increasing N deposition, explaining 9.5% and 1.1% of the variance, respectively. …”
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The status of forward osmosis technology implementation by Awad, Abdelrahman M.

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Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-analysis of Safety and Efficacy by Yi F.

“…Random effect summary estimates were calculated as standardized mean differences and odds ratios with 95% confidence intervals for continuous and binary outcomes. …”
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Privacy-preserving federated learning cyber-threat detection for intelligent transport systems with blockchain-based security by Moulahi, Tarek

“…Subsequently, by using blockchain and by applying an aggregation strategy to different models, models from the previous step were uploaded in a smart contract. Lastly, we returned the updated models to the vehicles. …”
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A new insight into the separation of oil from oil/water emulsion by Fe3O4?SiO2 nanoparticles by Elmobarak W.F.

“…In contrast, the value achieved for the seawater injection was 76.5%. For the oil recovery process, the Fe3O4 was applied for the inhibition (i.e., decrease) of oil sedimentation, and the SiO2 NPs were applied for wettability alteration and IFT reduction. …”
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Box-Behnken approach for optimization of Cr(III) removal from a real tanning effluent using powdered marble by Boujelben, R.

“…The results showed that the maximum uptake (> 99%) was obtained at a chromium initial concentration of 0.758�g/L, pH = 5.0 and using 6% (w:v) of powdered marble. Adsorption isotherm was satisfactorily described by Langmuir model. …”
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Could Vagus nerve stimulation influence bone remodeling? by Tamimi, Ahmad

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Topiramate monotherapy for weight reduction in patients with type 2 diabetes mellitus: A systematic review and meta-analysis by Paravattil, Bridget

“…Results: Of the 284 studies identified, 5 studies fulfilled the inclusion criteria. Topiramate decreased weight by a mean difference of 3.4 kg (95% CI, -3.79 to -3.04) compared to placebo. …”
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... by Thirumal Kumar, D

“…We also performed a virtual screening analysis with 19 AKT inhibitors obtained from the Selleck Chemicals website those satisfied the Lipinski rule of 5. …”
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Drive-up INR testing and phone-based consultations service during COVID-19 pandemic in a pharmacist-lead anticoagulation clinic in Qatar: Monitoring, clinical, resource utilization... by Alhmoud, Eman N.

“…Combined with teleclinics, using drive-up fingerstick International normalized ratio (INR) testing was recommended to decrease exposure risk of anticoagulation patients. …”
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Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation by Bansode, Rishipal

“…These applications give solid organic municipal wastes promising potential as precursors for value-added biochars with varied physicochemical characteristics allowing them to be used not only as an alternative to bio-waste management and greenhouse gas mitigation but also as means to improve depleted soil. We hypothesize that soil deficiencies in soil can be remedied by the application of biochars that are custom-designed to possess the right physicochemical characteristics suitable to improve soil fertility. …”
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Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma by Munusamy, Shankar

“…Results: hour annonacin treatment caused a significant and dose-dependent decrease in the viability of CaKi-2 cells, i.e., 42% in 0.5 ?…”
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Limiting the Rise in Core Temperature During a Rugby Sevens Warm-up With an Ice Vest. by Taylor, Lee

“…Athletes in VEST had a lower ΔTc [mean (SD) VEST 1.3°C (0.1°C); CONTROL 2.0°C (0.2°C)] from pre-warm-up to post-warm-up [effect size (ES) ± 90% confidence limit; -1.54; ±0.62] and Tc peak [mean (SD) VEST 37.8°C (0.3°C); CONTROL 38.5°C (0.3°C)] at the end of the warm-up (-1.59; ±0.64) compared to CONTROL. …”
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Effects of Turbulence Intensity and Biogas Composition on the Localized Forced Ignition of Turbulent Mixing Layers by d’Auzay, C. Turquand

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The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets by Cenciarelli, Carlo

“…In the last decade Stat3 has gained attention as therapeutic target in cancer but there is not yet any approved Stat3-based glioma therapy. Herein, we report that exposure to a Stat3/5 inhibitor, induced apoptosis either in shHes1-CSC or control cells. …”
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