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Profiling of the Differentially Expressed Genes of Inflammation and Angiogenesis of Human Brain Microvascular Endothelial Cells Evoked by Cell Injury In-Vitro to Mimic Acute Ischem...
Published 2020“…Acute IS (AIS) injury of PHBMEC is not well characterized in terms of its consequences on cell functions using genomic function profiling. In our study, we aimed to establish a new model of an acute in-vitro ischemic stroke, within a time limit of 2 hrs., with depriving whole nutrients and not just glucose, under hypoxic condition, in a model we created as oxygen nutrients deprivation (OND). …”
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Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
Published 2020“…MYBPC3 variants genotype–phenotype associations remain poorly understood. We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …”
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Centrifugal Compressor Spiral Dry Gas Seal Simulation Working at Reverse Rotation
Published 2013“…Unidirectional dry gas seal may experiences reverse rotation when equipped in a centrifugal compressor. This paper describes how the reverse rotation effects on the spiral unidirectional dry gas seal performance and pressure distribution inside the gas film, also an investigation of using a different herringbone shape grooves configurations has been done using ANSYS FLUENT 14.5 CFD simulation. …”
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Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM)
Published 2023“…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …”
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The Association between Zinc and Copper and Cardiometabolic Risk Factors in Adults
Published 2021“…High Zn/Cu ratio increased the prevalence of low HDL (4.508; p?0.001) and MetS (5.570; p?0.01). These findings suggest that high Cu levels are associated with a protective effect on DBP, HDL, and MetS and that high plasma Zn/Cu ratio is associated with the risk of low HDL and MetS. …”
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