Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

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Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Spatial training decreases the association between Ndfip1 and Nedd4 and decreases endogenous Beclin 1 ubiquitination in the hippocampus. by Wei-Lun Hsu (1756123)

“…Endogenous Beclin 1 ubiquitination level is decreased in Nedd4 siRNA-transfected rats (t_1,6 = 5.78, <i>p</i> = 0.001). …”

Predicted steady state distribution of the percent of TDLs in a 1) control animal, 2) following increased in the average residence time of lymphocytes in the lung (20 fold, from 26 seconds to 9 minutes) due to, for example, inflammation in the lung; 3) following a decreased entrance rate of TDLs into lymph nodes and Peyer's patches (20 fold, e.g., by using anti CD62L antibody); 4) following a decreased exit rate of TDLs from lymph nodes and Peyer's patches (5 fold, e.g., using FTY720). by Vitaly V. Ganusov (142019)

Genes whose expression was decreased by 1 mM ouabain by more than 2-fold. by Larisa V. Smolyaninova (3600053)

<i>T</i>_m values of SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

In the absence of chloride, two-fold decrease in [Na⁺]_e shifted GLT-1a E_rev by −28 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…<b>(C)</b> I-V curves of DHK sensitive currents obtained form <b>(B)</b> as a result of subtractions of averages of 2 I-V curves in presence of DHK from averages of 4 I-V curves in the absence of DHK at corresponding [Glu^-]_e and [Na⁺]_e. …”

Absence of adaptive immunity decreases tumor cell damage in MDR1A deficiency. by Eva Maria Hennenberg (4234018)

KRAP−/− Mice Showed Decreased Weight-Gain and Decreased Adiposity. by Takahiro Fujimoto (268158)

p35 siRNA knockdown decreased Cdk5 activity, diminished WT1 expression and viable cell numbers, but did not affect a cell apoptosis marker as detected by WB. by Ya-Li Zheng (454837)

“…C. p35 siRNA reduced Cdk5 activity. D. Western blotting analysis showed a decline of WT1 expression in p35 siRNA podocytes (upper panel, lane 2 compared to lane 1, p = 0,048), but did not affect cleaved caspase 3 expression (middle panel, lane 2 compare with lane 1). …”

Motion of C1-GAP domain of WT and mutant RhoGAPs interacting with RhoA substrate. by Zen Kouchi (14898435)

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Motion of RhoA protein bound to the C1-GAP domain of WT or mutant RhoGAPs. by Zen Kouchi (14898435)

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LuxR G37V has decreased DNA-binding activity. by Chelsea A. Simpson (9579303)

A heat map was generated for all the miRs utilized in the array, as a function of a fold change from referent control values. by Stephanie L. Samani (17896610)

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Absence of LFA-1 results in decreased numbers of NKT cells within the regenerating liver. by Ann-Kathrin Jörger (3559358)

Fold change of TIL subsets in paired TNBCs (N = 12 pts including 10 prim-met, and 2 met-met specimens) using log2 ratio of metastatic versus primary TNBC (n = 10, ●) or second recu... by Ting-Fang He (5210948)

Deficiency of Nmnat3 in mice does not decrease the NAD level in mitochondria. by Masashi Yamamoto (407190)

ERK signaling and expression of β-arrestin2 in Ang II–induced mouse AAA models as well as in WT or Klf5^−/− VSMCs. by Dong Ma (584680)

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Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

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Inhibition of Rab5 Activity Decreases Fluid-Phase Uptake by Carsten Schnatwinkel (48)