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mg decrease » _ decrease (Expand Search), we decrease (Expand Search), mean decrease (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
10 mg » 10 mm (Expand Search)
mg decrease » _ decrease (Expand Search), we decrease (Expand Search), mean decrease (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
10 mg » 10 mm (Expand Search)
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566
OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts.
Published 2019“…After 4 weeks, when the tumor size was approximately 100 mm<sup>3</sup> (T<sub>0</sub>) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”
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567
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568
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569
Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner
Published 2017“…Compared with vehicle control treatment, bortezomib pretreatment significantly decreased the maximal transport velocity (V<sub>max</sub>) of OATP1B3-mediated transport of CCK-8 (92.25 ± 14.2 vs. 133.95 ± 15.5 pmol/mg protein/min) without affecting the affinity constant (K<sub>m</sub>) values. …”
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570
GluN2A(D731N) enhances sensitivity to endogenous proton and zinc ions.
Published 2017“…<p>(<b>A</b>) The composite proton concentration-response curves show an enhanced sensitivity of the GluN2A(D731N)-containing receptors to proton compared to the WT NMDA receptors; the abscissa shows hydrogen ion activity. …”
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571
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572
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573
CD43<sup>-/-</sup> septic mice exhibit decreased frequencies of apoptotic CD8<sup>+</sup> T<sub>EM</sub> as compared to WT septic mice.
Published 2018“…D) There was a significant decrease in apoptosis of CD44<sup>HI</sup> CD62L<sup>LO</sup> CD8<sup>+</sup> T<sub>EM</sub> in CD43<sup>-/-</sup> septic mice compared to WT septic mice (10.3±1.1 vs 17.9±1.9, p = 0.006). …”
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574
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575
Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg
Published 2023“…The trabecular bone volume over total volume (BV/TV) in J<sub>H</sub><sup>-/-</sup> mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5<sup>-/-</sup> and J<sub>H</sub><sup>-/-</sup>λ5<sup>-/-</sup> mice demonstrated a severe decrease in trabecular bone mass. …”
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576
Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg
Published 2022“…The trabecular bone volume over total volume (BV/TV) in J<sub>H</sub><sup>-/-</sup> mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5<sup>-/-</sup> and J<sub>H</sub><sup>-/-</sup>λ5<sup>-/-</sup> mice demonstrated a severe decrease in trabecular bone mass. …”
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577
Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg
Published 2023“…The trabecular bone volume over total volume (BV/TV) in J<sub>H</sub><sup>-/-</sup> mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5<sup>-/-</sup> and J<sub>H</sub><sup>-/-</sup>λ5<sup>-/-</sup> mice demonstrated a severe decrease in trabecular bone mass. …”
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578
Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg
Published 2022“…The trabecular bone volume over total volume (BV/TV) in J<sub>H</sub><sup>-/-</sup> mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5<sup>-/-</sup> and J<sub>H</sub><sup>-/-</sup>λ5<sup>-/-</sup> mice demonstrated a severe decrease in trabecular bone mass. …”
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579
Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg
Published 2023“…The trabecular bone volume over total volume (BV/TV) in J<sub>H</sub><sup>-/-</sup> mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5<sup>-/-</sup> and J<sub>H</sub><sup>-/-</sup>λ5<sup>-/-</sup> mice demonstrated a severe decrease in trabecular bone mass. …”
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580
Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg
Published 2022“…The trabecular bone volume over total volume (BV/TV) in J<sub>H</sub><sup>-/-</sup> mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5<sup>-/-</sup> and J<sub>H</sub><sup>-/-</sup>λ5<sup>-/-</sup> mice demonstrated a severe decrease in trabecular bone mass. …”