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Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries
Published 2022“…Consumption of ketoconazole slowly declined, with 5.04% annual decrease, probably due to labelling changes in 2013 to reflect hepatotoxicity concerns. …”
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424
Pd nanocrystals encapsulated in MOF-derived Ni/N-doped hollow carbon nanosheets for efficient thermal CO oxidation: unveiling the effect of porosity
Published 2023“…This is evidenced in the great ability of Pd/Ni-MOF-HNC to utterly oxidize CO at a lower complete conversion temperature (T100) of 114.5 °C compared with Pd/Ni-MOF-NC (153.8 °C) and Pd/C (201.5 °C) under atmospheric pressure. …”
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425
The influence of environmental and core temperature on cyclooxygenase and PGE2 in healthy humans
Published 2021“…Tc [mean (range)] increased in hot [+ 0.8 (0.4–1.2) °C; p < 0.0001; effect size (ES): 2.9], decreased in cold [− 0.5 (− 0.8 to − 0.2) °C; p < 0.0001; ES 2.6] and was unchanged in thermoneutral [+ 0.1 (− 0.2 to 0.4) °C; p = 0.3502]. …”
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426
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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427
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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428
Flight Scheduling in the Airspace
Published 2016“…In this study, we developed a scatter search (SS) to deal with larger instances. …”
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429
Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications
Published 2022“…The increment changed to 1.82%, 8.16%, and 22.31% for a pitch = 5 mm and 1.01%, 5.96%, and 21.38% for a pitch = 2.5 mm. …”
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430
Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes
Published 2021“…We assessed how macroclimate and atmospheric inorganic N deposition under current and predicted scenarios (RCP 2.6, RCP 8.5) might affect litter mass loss measured after 3 and 12 months. …”
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431
Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo
Published 2019“…The formulation of silymarin-HSA nanoplex showed a spherical shape with an average diameter between 50 nm and 150 nm, hydrodynamic radius of 188.3 nm, zeta potential of −26.6 mV, and a drug loading of 97.3%. …”
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432
Privacy-preserving federated learning cyber-threat detection for intelligent transport systems with blockchain-based security
Published 2022“…Subsequently, by using blockchain and by applying an aggregation strategy to different models, models from the previous step were uploaded in a smart contract. Lastly, we returned the updated models to the vehicles. …”
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433
Signaling pathways activated by PACAP in MCF-7 breast cancer cells
Published 2018“…In addition, PACAP increased the phosphorylation levels of STAT1, Src and Raf within seconds, confirming their involvement in early stages of PACAP signaling whereas maximal phosphorylation of AKT, ERK and p38 was reached 10 to 20 min later. Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …”
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Experimental Investigation of Foam drilling fluid using Visualization Technique
Published 2021“…The experiments were conducted in a 6.16 m long horizontal pipe with 2.5 in. inner diameter and 4.5 in. outer diameter and annular diameter ratio of 1.8. …”
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Utilization of Emergency Services by Children with Asthma in Qatar
Published 2022“…Background: Asthma is a leading chronic disease in children worldwide, which if left untreated or poorly controlled, can lead to altered lung function and poor quality of life. 1 Early detection and improved control of asthma are recommended to decrease utilization of emergency services and hospitalizations. …”
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The Separation of Emulsified Water/Oil Mixtures through Adsorption on Plasma-Treated Polyethylene Powder
Published 2021“…The efficiency of the plasma-treated LDPE powder in oil removal was found to be dependent on the initial oil concentration. It decreased from 96.7% to 79.5% as the initial oil concentration increased from 75 ppm to 200 ppm. …”
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Dynamic stretching alone can impair slower velocity isokinetic performance of young male handball players for at least 24 hours
Published 2019“…Eight young male, elite handball players (age: 16.1�5.1 years) were tested prior to-, 3-minutes and 24-hours following the three conditions (DS, SS, Control) in a randomized and counterbalanced order. …”
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440
Hydrogen Production via Ethanol Decomposition over Bimetallic Catalyst
Published 2016“…The reaction between NH3 and HNO3 released during decomposition of glycine and metal nitrate respectively produces the energy required for single step combustion synthesis. At higher value of φ, the reactive medium generates H2 rich reducing environment to convert metal oxide to metallic form Bimetallic CuCo were synthesized from the aqueous solution of cobalt nitrate (Co(NO3)2·6H2O), copper nitrate (Cu(NO3)2·6H2O) and glycine (C2H5NO2) in solution combustion synthesis (SCS) method using a fuel to oxidizer ratio of φ 0.5, 1, 1.75 and 2.5. …”
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