Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Hematoxylin and eosin staining and Sirius red staining were performed to identify bone formation in vivo. …”

A potential therapeutic agent for sickle cell anaemia by Nature Research (16552612)

“…Also, supplementing patients with substances that possess antioxidant properties could reduce the complications of the disease,” says biochemist Lamia Al-Naama, the lead author of the paper. Substances that decrease the frequency of episodes of red blood cell destruction or employing molecular approaches that can reduce ROS production could alter the course of the disease and the incidence of associated complications, she adds.…”

Magnesium-reinforced PMMA composite scaffolds: Synthesis, characterization, and 3D printing <i>via</i> stereolithography by Ambreen Afridi (22224310)

“…Notably, pure PMMA exhibited the highest tensile strength, 26.23 ± 0.14 MPa and an elastic modulus of 707.81 MPa, while PMMA resin/1% Mg showed the lowest strength (19.46 ± 0.25 MPa) and modulus (392.88 MPa), indicating a decrease in mechanical integrity with higher Mg content. …”

Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy by Olfa Khalifa (10914452)

“…Analysis of the Oil Red O staining showed that Ex-4 significantly reduces steatosis. …”

Insights Into SARS-CoV-2 S1-RBD-ACE2 Interaction Using Computational Tools and Membrane Microarray Platform by Angelin Mary Philip (21547421)

“…This revealed clustering of S1-RBD on membrane and more importantly, a depletion of the Omicron S1-RBD from membrane corrals, which was not seen with the WT S1-RBD. …”

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…To characterise the impact on muscle degradation, we tested LAT2 KO mice in cancer‐associated cachexia, streptozocin‐induced Type‐1 diabetes, and ageing models.</p><h3>Results</h3><p dir="ltr">LAT2KO mice experienced a notable reduction in body weight during fasting (WT:14% and LAT2KO:18%, <i>p</i> = 0.02), with a greater reduction in fat mass (0.5‐fold, <i>p</i> = 0.013) and a higher relative retention of muscle mass (1.3‐fold, <i>p</i> = 0.0003) compared with WT. …”

Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells by Hafsa Madni (22674428)

“…Furthermore, mature adipocytes differentiated from <i>FOXA2</i> KO derived MSCs showed elevated apoptosis indicated by the Annexin V staining, lipid accumulation detected by Oil Red O staining, and decreased expression of adipocyte maturation and functional genes utilizing the RT-PCR technique. …”

Production and investigation of flexible nanofibers of sPEEK/PVP loaded with RuO2 nanoparticles by Mariem Chamakh (14150481)

Impact of aluminium acetate particles size on the gelation kinetics of polyacrylamide‐based gels: Rheological and molecular simulation study by Ahmed Hamza (7224470)

“…The addition of bentonite at low crosslinker concentrations (0.5–1 wt.%) did not decrease the gel strength of 7 wt.% PAM/1 wt.% AlAc significantly. …”

Adaptive Effects of Seeing Green Environment on Psychophysiological Parameters When Walking or Running by Walid Briki (688845)

“…Study 2 showed that running in a green environment was associated with an increased level of perceived exertion at similar speeds (compared to other color conditions), while exposure to red induced a significant decrease in the level of tension. …”

Corrosion Evaluation of 316L Stainless Steel Exposed to CNT-Water Nanofluid by Dana Abdeen (18147583)

“…A maximum inhibition of 61% was achieved in 0.1 wt.% CNTs nanofluid at room temperature. Further increase in the CNTs concentrations and in nanofluid’ temperature showed to decrease the corrosion performance.…”

A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase by Ahmed S. Ibrahim (10049522)

“…Fluorescein angiography and retinal albumin leakage showed a significant decrease in retinal hyperpermeability in streptozotocin-induced diabetic mice lacking 12/15-LOX compared with diabetic WT mice. …”

Isothermal Crystallization Kinetics and Morphology of Double Crystalline PCL/PBS Blends Mixed with a Polycarbonate/MWCNTs Masterbatch by Thandi P. Gumede (18112762)

“…The nanocomposites contained 1.0 and 4.0 wt% MWCNTs. The blends showed a sea-island morphology typical of immiscible blends. …”

Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study by Houssein H., Ayoub

“…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …”
Get full text
Get full text
Get full text

SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines by Hadeel T. Zedan (12535521)

“…We analyzed ADCC activity targeting SARS‐CoV‐2 spike (S) and nucleocapsid (N) proteins in convalescent sera following WT SARS‐CoV‐2‐infection (<i>n</i> = 91), including symptomatic and asymptomatic infections, omicron‐infection (<i>n</i> = 8), COVID‐19 vaccination with messenger RNA‐ (mRNA)‐ (BNT162b2 or mRNA‐1273, <i>n</i> = 77), adenovirus vector‐ (<i>n</i> = 41), and inactivated virus‐ (<i>n</i> = 46) based vaccines, as well as post‐mRNA vaccination BTI caused by omicron (<i>n</i> = 28). …”

Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles by Muneer M. Ba-Abbad (14151660)

“…<p dir="ltr">In this study, the nanoparticles (NPs) of ZnO and Co²⁺ ions doped ZnO (doped ZnO) were incorporated into a matrix of polysulfone (PSf) membranes to enhance their surface properties prepared using a simple wet phase inversion technique. The hybrid PSf membranes were fabricated with 0.5 wt. % of ZnO and doped ZnO NPs. …”

Mechanisms behind the immediate effects of Roux-en-Y gastric bypass surgery on type 2 diabetes by Roland E Allen (19187023)

COVID-19 and Anemia: What Do We Know So Far? by Luai Abu-Ismail (10712857)

“…Anemia, a common hematologic disorder, is characterized by the reduced oxygen-carrying capacity of red blood cells. The existing literature has a suspected link between anemia and severe COVID-19 cases. …”

Stability and thermophysical properties test of carbide-derived carbon thermal fluid; a comparison between functionalized and emulsified suspensions by Ismail W. Almanassra (14151321)

“…The results demonstrated that the thermal conductivity enhancement was independent of temperature, decreases with gum-Arabic concentration, and significantly enhanced with CDC loading with a maximum enhancement of 26.1% for 0.3 wt% functionalized CDC. …”

Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO₂ intercooled and reheated cycles under design and off‐d... by Wahib A. Al‐Ammari (18877408)

“…At optimized conditions (<i>P</i>_c,o = 30 MPa, Pc,o = 8 MPa, TIT = 744°C, CIT = 30°C [wet‐cooling]), the ICC shows superior energetic performance (52.08%) compared to 47.97% for DRC, 49.20% for PIC, and 48.62% for RHC. …”