Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

No effects of trehalose treatment in mitochondria length in HT fibroblasts. by Collin M. MacLeod (17512385)

Magnetic resonance imaging (MRI) of liver, heart, lumbar spine, and iliac crest at baseline and at the end of follow-up. by Lucas L. A. Nunes (19360381)

Analysis of tumour vasculature with the addition of more HT groups. by Deepa Sharma (278210)

“…The vasculature becomes less evident in the treated groups, with decreasing numbers of stained blood vessels. Images were taken at a 20x objective lens, and the scale bar denotes ~50μm. …”

Serum samples and 50% NAI values. Serum samples taken from CEIRS study. by Harrison Powell (9040128)

The PRAME-AS knockout cells showed a decrease in migration, proliferation, stemness, and viability. by Zahra Hosseininia (22265113)

Normalized pressure pain thresholds (PPTs) (mean ± SEM) at start, middle, end and 5 minutes after a standardized tourniquet test. by Jeanette Tour (10790855)

Fx treatment abrogates the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> infection of human U-87 MG astroglioma cells. by Glaucia Vilar-Pereira (686134)

The primers related to FAM50A. by Longhai Li (4052044)

“…Knockdown of FAM50A decreased cell proliferation ability, the proportion of EdU positive cells, and the number of CRC cell colonies, whereas overexpressing FAM50A promoted proliferative phenotypes. …”

Fig 1 - by Byung Chul Kang (1905025)

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Protective effects of DEX on TNF-α-induced cochlear hair cells loss in cochlear explants. by Byung Chul Kang (1905025)

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Protective effect of DEX on cell viability, ROS generation, and expression of apoptosis-related proteins in TNF-α-treated cells. by Byung Chul Kang (1905025)

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Effects of TNF-α on the cochlear hair cells in middle-turn cochlear explants. by Byung Chul Kang (1905025)

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Effects of DEX and TNF-α on intracellular ROS accumulation and expression of apoptosis-related proteins. by Byung Chul Kang (1905025)

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Attenuation of TNF-α-induced apoptosis by DEX pretreatment. by Byung Chul Kang (1905025)

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Attenuation of TNF-α-induced apoptosis through pretreatment of DEX in cochlear explants. by Byung Chul Kang (1905025)

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THRα/β EC₅₀ values and selectivity of test compounds. by Xuan G. Luong (9761423)

Multiple logistic regression model exploring factors associated with >50% seizures reduction at month 4. by Michel Mandro (2637532)

CaD prevents the decrease in tight junction protein levels and the increase in HUVECs permeability induced by VEGF₁₆₅. by Florence Njau (8298954)