MCP-1-deficiency decreased CD11c-expressing cells via impairing the production of ROS and decreased activation of PLCγ2, Akt, and ERK upon M-CSF stimulation in BMM. by Woon-Ki Kim (447798)

“…<p>BMMs from WT (open bar) and MCP-1-KO mice (oblique-lined bar) were incubated in the presence of M-CSF (30 ng/ml) with U73122 (10 µM), Akt inhibitor IV (0.3 µM), PD098059 (5 µM), DPI (50 nM), NAC (3 mM), or H₂O₂ (300 µM) for 4 d (A). *, <i>P</i><0.05; ***, <i>P</i><0.001 compared with vehicle-treated WT cells. …”

Blocking C5L2 decreased C5a-primed neutrophils for ANCA-induced degranulation. by Jian Hao (160736)

Increased endodiastolic volume and decreased ejection fraction in GJB4-deficient zebrafish. by Ryuji Okamoto (614374)

Binding of <i>PC3/Tis21</i> to the <i>Id3</i> promoter and corresponding decrease of <i>Id3</i> mRNA. by Stefano Farioli-Vecchioli (256006)

“…(<b>B</b>) ChIP analysis of <i>PC3</i> binding to the <i>Id3</i> promoter in PC12 cells, treated as shown in (<b>A</b>). A scheme above the graph describes the <i>Id3</i> gene and the promoter region analyzed, 700 nt 5′ to the transcription start. …”

Activation, inactivation, and deactivation kinetics differ between Ca_V3.3 WT and variants as well as among the variants. by Yousra El Ghaleb (22075892)

Subjects:

Deletion of TXNIP decreases thioredoxin levels under hyperoxic conditions. by Mohammed A. Abdelsaid (287140)

“…<p>WT and TKO mice were subjected to 5 days hyperoxia (p7–12). …”

Decreased remyelination initiation is observed in Scribble cKO mice following focal demyelination in corpus callosum. by Andrew A. Jarjour (343100)

“…In the contralateral (unlesioned) hemisphere (CL), no difference was seen in the proportion of axons in the corpus callosum that were myelinated in Scribble cKO compared to wild-type animals (A–C). Fewer remyelinated axons were observed in corpus callosum in the lesion area in Scribble cKO mice (E) relative to controls (D) as quantified in F; 0.4–0.5 μm: WT = 80.0% ± 9.8%, cKO = 41.3% ± 8.9% myelinated; 0.5–0.6 μm: WT = 79.4% ± 6.3%, cKO = 41.5% ± 9.5% myelinated; 0.6–0.7 μm: WT = 91.6% ± 3.0%, cKO = 44.3% ± 8.7% myelinated; >0.7 μm: WT = 92.7% ± 1.9%, cKO = 47.9% ± 2.5% myelinated. …”

Tax expression is associated with decreased cellular motility. by Saumya Ramanayake (7879091)

Subjects:

Decrease in vRNA in brain during antiretroviral therapy. by Sonny R. Elizaldi (9684796)

Preserved NSS at 2 and at 24 hours following ischemia and decreased infarct volume in PAR1 KO mice 24 hours following ischemic stroke. by Efrat Shavit-Stein (3186678)

“…(C) Total infarct volume is significantly lower in PAR1 KO mice compared to control (t-test, WT = 6, PAR1 KO = 6). (D) Infarct volume decreases as a function of distance from the ischemic core (slices #5&6). …”

A homozygous point mutation in the <i>Mrps34</i> gene causes a decrease in the MRPS34 protein. by Tara R. Richman (713532)

“…The 5′- and 3′-untranslated regions are shown as grey boxes and the predicted mitochondrial targeting sequence is shown as a black box (predicted using MitoProtII, [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005089#pgen.1005089.ref040" target="_blank">40</a>]). …”

Fluoxetine decreases TOPFlash firefly luciferase reporter activity. by Kentaro Miyamoto (123271)

MK-STYX decreases RhoA activation. by Brittany M. Flowers (670483)

“…Anti-phospho-cofilin antibody showed that MK-STYX decreased cofilin phosphorylation in non-stimulated cells relative to the MK-STYX shRNA-A. …”

<i>Dmd^mdx</i> rats are characterized by muscle weakness and by a decrease in a spontaneous activity. by Thibaut Larcher (331981)

“…<i>Dmd^mdx</i> rats showed fatigue with a decreased force grip across the five pulls, and significant values are obtained for the two last trials that were reduced to ∼70% when compared to Trial 1. …”

Total RNAP II levels decrease during WT HSV-1 KOS infection. by Mark Ou (474248)

NR4A1 expression does not decrease after inhibition of p38, JNK and Src pathways. by Glenda Eger (636934)

Resveratrol decreased intracellular levels of R5P. by Mohd Askandar Iqbal (324124)

“…<p>R5P is a pentose phosphate pathway intermediate, an important marker for anabolism (nucleotide biosynthesis). …”

Decreased Tks5 expression results in neural crest-derived defects. by Danielle A. Murphy (212554)

“…<p>(A–B) Melanophores within the trunk region above the yolk sac extension in control MO-injected and Tks5 MO-injected embryos were qualitatively (A) and quantitatively (B) analyzed. n = 15 embryos and SEM is shown by bar. p values obtained from Student's t-test. ** denotes p<0.01. …”

Nicotine decreased Wnt5a expressions in SK-BR-3 cells. by Masanori A. Murayama (5774585)

PGC-1β KO mice show a specific decrease in Mfn2 expression in skeletal muscle. by Marc Liesa (35879)