Fitting relationship of E₅₀. by Junxia Zhou (14381598)

Fitting curve of E₅₀. by Junxia Zhou (14381598)

The concentrations of VEGFR2 secreted from the vertebral endplate during organ culture (ng/L, n = 4, x ± s). by Jia-Wen Zhan (9028652)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

Preliminary search for price decreases for the period 01 Jan. 2021–14 Jun. 2022. by Jevgeni Tarassov (13889285)

Measurement of mitochondrial superoxide anion production in HL-1 cells exposed for 12 or 72h to LG, NG, HG or IHG. by Patrick Mordel (17020879)

CONSORT flowchart. by Jaskiran Kaur (160829)

Baseline characteristics of study subjects. by Jaskiran Kaur (160829)

Represents the levels of biomarkers as baseline and follow up in placebo and cholecalciferol group. by Jaskiran Kaur (160829)

Development of a CRISPR/Cas-Based Detection Platform for Tracking Decreased Susceptibility to Cephalosporins in Neisseria gonorrheae by Ziyuan Zhao (2889005)

“…MIRCA enables multiplex detection of <i>Ng</i> and single-nucleotide polymorphisms in resistance-associated genes within 40 min, with high specificity and sensitivity (10–20 copies/reaction). …”

Representative immunohistochemistry images of PCNA expression in renal tissues among CG, NG, NVG, and NVRG (×400). by Jian-feng Li (8667645)

U937 cells were seeded at ~1 × 10⁵ cells per well. by Janani Madhuravasal Krishnan (19736002)

oAβ enhances lysosomal acidification in NG and HG mixed glia cultures. by Yung-Cheng Huang (3443450)

Fitting curve of rock E₅₀. by Junxia Zhou (14381598)

The expression of <i>Collagen II</i> and <i>Collagen X</i> in cartilage cells were significantly decreased after siRNA treatment. by Fei Ye (339913)

Fig 10 - by Jie He (132999)

IL-10 production in response to IL-27 is impaired in Chagas disease patients with severe cardiomyopathy. by María Ailén Natale (6843422)

CXCL10 production is enhanced in the setting of HIV and HBV co-infection in vitro and decreased with the addition of antiretroviral agents efavirenz or raltegravir. by Kasha P. Singh (9354307)

Decreased transcription of <i>prs</i> results in decreased growth. by Javiera Norambuena (137228)