Fibrin concentration of 10,000 simulations compared to experimental data of blood clotting over collagen/ TF under venous flow rate. حسب Jason Chen (15937)

الموضوعات:

Transient convection-diffusion of thrombin into and out of a fibrin domain exposed to venous flow. حسب Jason Chen (15937)

الموضوعات:

Evidence of Formation of 1–10 nm Diameter Ice Nanotubes in Double-Walled Carbon Nanotube Capillaries حسب Yuan Liu (88411)

"…However, the single-walled INTs reported in the literature all possess subnanometer diameters (<1 nm). Herein, based on systematic and large-scale molecular dynamics simulations, we demonstrate the spontaneous freezing transition of liquid water to single-walled INTs with diameters reaching ∼10 nm when confined to capillaries of double-walled carbon nanotubes (DW-CNTs). …"

Evidence of Formation of 1–10 nm Diameter Ice Nanotubes in Double-Walled Carbon Nanotube Capillaries حسب Yuan Liu (88411)

"…However, the single-walled INTs reported in the literature all possess subnanometer diameters (<1 nm). Herein, based on systematic and large-scale molecular dynamics simulations, we demonstrate the spontaneous freezing transition of liquid water to single-walled INTs with diameters reaching ∼10 nm when confined to capillaries of double-walled carbon nanotubes (DW-CNTs). …"

Evidence of Formation of 1–10 nm Diameter Ice Nanotubes in Double-Walled Carbon Nanotube Capillaries حسب Yuan Liu (88411)

"…However, the single-walled INTs reported in the literature all possess subnanometer diameters (<1 nm). Herein, based on systematic and large-scale molecular dynamics simulations, we demonstrate the spontaneous freezing transition of liquid water to single-walled INTs with diameters reaching ∼10 nm when confined to capillaries of double-walled carbon nanotubes (DW-CNTs). …"

Evidence of Formation of 1–10 nm Diameter Ice Nanotubes in Double-Walled Carbon Nanotube Capillaries حسب Yuan Liu (88411)

"…However, the single-walled INTs reported in the literature all possess subnanometer diameters (<1 nm). Herein, based on systematic and large-scale molecular dynamics simulations, we demonstrate the spontaneous freezing transition of liquid water to single-walled INTs with diameters reaching ∼10 nm when confined to capillaries of double-walled carbon nanotubes (DW-CNTs). …"

Evidence of Formation of 1–10 nm Diameter Ice Nanotubes in Double-Walled Carbon Nanotube Capillaries حسب Yuan Liu (88411)

"…However, the single-walled INTs reported in the literature all possess subnanometer diameters (<1 nm). Herein, based on systematic and large-scale molecular dynamics simulations, we demonstrate the spontaneous freezing transition of liquid water to single-walled INTs with diameters reaching ∼10 nm when confined to capillaries of double-walled carbon nanotubes (DW-CNTs). …"

K562 cells were treated with 40 nM of miR-214 mimics or a negative mimics control for 24 h, followed by treatment with 50 μM of hemin for 48 h. حسب Tipparat Penglong (164413)

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. حسب Marek J. Kobylarz (9292599)

Discovery of a Trifluoromethoxy Cyclopentanone Benzothiazole Receptor-Interacting Protein Kinase 1 Inhibitor as the Treatment for Alzheimer’s Disease حسب Yi Sun (118759)

"…<b>SZM679</b>, a highly specific RIPK1 inhibitor (<i>K</i>_d,RIPK1 = 8.6 nM, <i>K</i>_d,RIPK3 > 5000 nM), was developed by our group with superior high antinecroptotic activity (EC₅₀ = 2 nM), and investigated to completely reverse the tumor necrosis factor-induced systemic inflammatory response syndrome. …"

Discovery of a Trifluoromethoxy Cyclopentanone Benzothiazole Receptor-Interacting Protein Kinase 1 Inhibitor as the Treatment for Alzheimer’s Disease حسب Yi Sun (118759)

"…<b>SZM679</b>, a highly specific RIPK1 inhibitor (<i>K</i>_d,RIPK1 = 8.6 nM, <i>K</i>_d,RIPK3 > 5000 nM), was developed by our group with superior high antinecroptotic activity (EC₅₀ = 2 nM), and investigated to completely reverse the tumor necrosis factor-induced systemic inflammatory response syndrome. …"

Discovery of a Trifluoromethoxy Cyclopentanone Benzothiazole Receptor-Interacting Protein Kinase 1 Inhibitor as the Treatment for Alzheimer’s Disease حسب Yi Sun (118759)

"…<b>SZM679</b>, a highly specific RIPK1 inhibitor (<i>K</i>_d,RIPK1 = 8.6 nM, <i>K</i>_d,RIPK3 > 5000 nM), was developed by our group with superior high antinecroptotic activity (EC₅₀ = 2 nM), and investigated to completely reverse the tumor necrosis factor-induced systemic inflammatory response syndrome. …"

Discovery of a Trifluoromethoxy Cyclopentanone Benzothiazole Receptor-Interacting Protein Kinase 1 Inhibitor as the Treatment for Alzheimer’s Disease حسب Yi Sun (118759)

"…<b>SZM679</b>, a highly specific RIPK1 inhibitor (<i>K</i>_d,RIPK1 = 8.6 nM, <i>K</i>_d,RIPK3 > 5000 nM), was developed by our group with superior high antinecroptotic activity (EC₅₀ = 2 nM), and investigated to completely reverse the tumor necrosis factor-induced systemic inflammatory response syndrome. …"

Discovery of a Trifluoromethoxy Cyclopentanone Benzothiazole Receptor-Interacting Protein Kinase 1 Inhibitor as the Treatment for Alzheimer’s Disease حسب Yi Sun (118759)

"…<b>SZM679</b>, a highly specific RIPK1 inhibitor (<i>K</i>_d,RIPK1 = 8.6 nM, <i>K</i>_d,RIPK3 > 5000 nM), was developed by our group with superior high antinecroptotic activity (EC₅₀ = 2 nM), and investigated to completely reverse the tumor necrosis factor-induced systemic inflammatory response syndrome. …"

Discovery of a Trifluoromethoxy Cyclopentanone Benzothiazole Receptor-Interacting Protein Kinase 1 Inhibitor as the Treatment for Alzheimer’s Disease حسب Yi Sun (118759)

"…<b>SZM679</b>, a highly specific RIPK1 inhibitor (<i>K</i>_d,RIPK1 = 8.6 nM, <i>K</i>_d,RIPK3 > 5000 nM), was developed by our group with superior high antinecroptotic activity (EC₅₀ = 2 nM), and investigated to completely reverse the tumor necrosis factor-induced systemic inflammatory response syndrome. …"

siRNA Knockdown of PKCδ decreases phosphorylation of VEEV capsid. حسب Brian D. Carey (6092747)

Primary endpoint analysis, i.e., time to first occurrence of combined event of 50% decrease in eGFR or ESRD. حسب Rozita Mohd (7411322)

Log reactivation results for exposures by 222 nm or 265 nm with or without UV-A 365 nm pre-treatment. حسب Daniel Ma (12698752)

24-hr treatment with 100nM M64HCl, 10μM PF573228, the combination of 100nM M64HCl and 10μM PF573228, 10μM PD98059, or the combination of 100nM M64HCl and 10μM PD98059 in migrating... حسب Sema Oncel (10152053)

الموضوعات:

24-hr treatment with 100nM M64HCl, 10μM PF573228, the combination of 100nM M64HCl and 10μM PF573228, 10μM PD98059, or the combination of 100nM M64HCl and 10μM PD98059 in migrating... حسب Sema Oncel (10152053)

الموضوعات: