MMR mutants show decreased mating-type silencing. by Qian Liu (135614)

“…MMR deletion strains (<i>pms1Δ</i>, <i>mlh1Δ</i>, and <i>msh2Δ</i>) displayed white with sectors colonies as compared to WT, indicating a loss of gene silencing at the telomere <i>ADE2</i> reporter. …”

MigC interacts with and decreases the activity of MurD. by Jeanette M. Critchlow (21553796)

For most sites, observed abundance decreases with size class. by Sarah L. Becker (6631253)

Loss of virulence in the SIN kinase mutants is characterized by decreased fungal burden and host response to infection. by Ana Camila Oliveira Souza (8180958)

“…<p><b>A)</b> Analysis of fungal burden by qPCR at day +4 post inoculation. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Preserved NSS at 2 and at 24 hours following ischemia and decreased infarct volume in PAR1 KO mice 24 hours following ischemic stroke. by Efrat Shavit-Stein (3186678)

“…(C) Total infarct volume is significantly lower in PAR1 KO mice compared to control (t-test, WT = 6, PAR1 KO = 6). (D) Infarct volume decreases as a function of distance from the ischemic core (slices #5&6). …”

Acinetobactin biosynthetic mutants exhibit decreased maximal growth and growth rates, as well as an increased lag time relative to WT <i>A</i>. <i>baumannii</i> ATCC 179789 when gr... by Jessica R. Sheldon (4785675)

Extended Ensemble Molecular Dynamics Study of Ammonia–Cellulose I Complex Crystal Models: Free-Energy Landscape and Atomistic Pictures of Ammonia Diffusion in the Crystalline Phase... by Toshifumi Yui (1768846)

“…Introducing hybrid quantum mechanical and molecular mechanics theory to the adaptive steered molecular dynamics simulation effectively lowered the heights of the PMF peaks to approximately 5 kcal/mol, accompanied by a slight decrease in the baseline. …”

Extended Ensemble Molecular Dynamics Study of Ammonia–Cellulose I Complex Crystal Models: Free-Energy Landscape and Atomistic Pictures of Ammonia Diffusion in the Crystalline Phase... by Toshifumi Yui (1768846)

“…Introducing hybrid quantum mechanical and molecular mechanics theory to the adaptive steered molecular dynamics simulation effectively lowered the heights of the PMF peaks to approximately 5 kcal/mol, accompanied by a slight decrease in the baseline. …”

Extended Ensemble Molecular Dynamics Study of Ammonia–Cellulose I Complex Crystal Models: Free-Energy Landscape and Atomistic Pictures of Ammonia Diffusion in the Crystalline Phase... by Toshifumi Yui (1768846)

“…Introducing hybrid quantum mechanical and molecular mechanics theory to the adaptive steered molecular dynamics simulation effectively lowered the heights of the PMF peaks to approximately 5 kcal/mol, accompanied by a slight decrease in the baseline. …”

CcnA mutation of Loop A decreases the interaction with the 5′ UTR of P2-<i>ctrA</i> mRNA and 5′ UTR of <i>gcrA</i> mRNA. by Wanassa Beroual (5314028)

Fig 5 - by Zhi Zhang (55283)

Image_5_Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue.jpeg by Vinit Upasani (4169677)

Dcp1a protein levels are decreased by KapB expression and Torin treatment. by Carolyn-Ann Robinson (13297009)

<b>Adipose TGR5 deletion promotes hepatic steatosis through decreasing adiponectin secretion in mice</b> by Jiahui Li (646449)

SLAMF6 knock down or knock out leads to a decrease in TCR activation. by Matthew A. Dragovich (6843362)

Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation - Fig 5 by Femke van Diggelen (6499112)

Activating cAMP synthesis decreases liberation of propionyl-CoA from cholesterol. by Kaley M. Wilburn (12060476)

An enhanced clot growth rate before in vitro fertilization decreases the probability of pregnancy by A. N. Balandina (6729380)