Search alternatives:
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
nm decrease » nn decrease (Expand Search), _ decrease (Expand Search), gy decreased (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), mean decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
10 nm » 100 nm (Expand Search), 10 mm (Expand Search)
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
nm decrease » nn decrease (Expand Search), _ decrease (Expand Search), gy decreased (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), mean decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
10 nm » 100 nm (Expand Search), 10 mm (Expand Search)
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Flow chart of the expression-based functional screen, with validation steps.
Published 2022Subjects: -
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Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
Published 2021“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
Published 2021“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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287
Fully Transparent and Rollable Electronics
Published 2015“…For handling purposes, carrier glass is used during fabrication, together with a very thin (∼1 nm) solution-processed carbon nanotube (CNT)/graphene oxide (GO) backbone that is first spin-coated on the glass to decrease adhesion of the CPI to the glass; peel strength of the CPI from glass decreases from 0.43 to 0.10 N/cm, which eases the process of detachment performed after device fabrication. …”
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Nanomolar Caffeic Acid Decreases Glucose Uptake and the Effects of High Glucose in Endothelial Cells
Published 2015Subjects: -
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Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease
Published 2015“…Here we tested whether lithium treatment would decrease levels of GFAP in a mouse model of Alexander disease. …”
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DataSheet_1_Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat.pdf
Published 2023“…Circulating exosomes of SGAs (as compared to those of AGAs) had a larger size at birth [146.8 vs 137.8 nm, respectively; p=0.02], and were in lower number at ages 2 [4.3x10<sup>11</sup>vs 5.6x10<sup>11</sup> particles/mL, respectively; p=0.01] and 7 [6.3x10<sup>11</sup>vs 6.8x10<sup>11</sup> particles/mL, respectively; p=0.006]. …”
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Four-fold decrease in [H<sup>+</sup>]<sub>e</sub> shifted GLT-1a E<sub>rev</sub> by −18 mV at both low and high glutamate concentrations.
Published 2015“…Arrows show GLT-1a E<sub>rev</sub> shifts. <b>(C)</b> Average GLT-1 E<sub>rev</sub> shifts at 37.5 μM and 600 μM are approximately equal when [H<sup>+</sup>]<sub>e</sub> was decreased from 40 to 10 nM.…”
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The decrease or inhibition of Hsp90 induced REST degradation.
Published 2019“…<p>(A) Effect of Hsp90α ASO on cell viability. Differentiated SH-SY5Y cells were transfected with different concentrations of Hsp90α ASO. …”