Search alternatives:
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
10 nn » 10 nm (Expand Search), 10 ng (Expand Search), 10 ns (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
10 nn » 10 nm (Expand Search), 10 ng (Expand Search), 10 ns (Expand Search)
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Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction
Published 2015“…</p><p>Conclusions</p><p>The levels of hepatic detoxification enzymes were significantly decreased in human obstructive cholestasis, and these decreases were positively associated with a marked reduction of FXR levels. …”
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22
Decrease of 4 Asp isomers at 70°C.
Published 2013“…<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058515#pone-0058515-g007" target="_blank">Figure 7a:</a> decrease of L-α-Asp with incubation of T6-Lα peptide at 70°C. …”
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Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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26
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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27
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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28
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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29
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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30
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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31
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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32
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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33
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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34
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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35
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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36
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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37
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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39
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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40
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”