The substitution F447L is adaptive for J4_S52-HVR1, while it decreases infectivity of parental J4 and J4_ΔHVR1 HCVcc. by Christina Holmboe Olesen (11154333)

VRK1 overexpression is seen in human breast cancer and is associated with decreased relapse-free survival. by Aye M. Mon (5714912)

“…The overall median rank of VRK1 mRNA overexpression was 947 (out of 19,273 measured genes) (p = 3.64x10^-28). Data for cancer subtypes are shown in boxes numbered 1–11: 1: benign breast neoplasm (rank 6459, 1.4 fold-change, NS), 2: breast carcinoma (rank 833, 1.5 fold-change, p = 3.83x10^-5), 3: breast phyllodes tumor (rank 512, 1.2 fold-change, p = 0.002), 4: ductal breast carcinoma in situ (rank 1969, 1.5 fold-change, p = 0.002), 5: invasive breast carcinoma (rank 1060, 1.6 fold-change, p = 1.28x10^-5), 6: invasive ductal and invasive lobular breast carcinoma (rank 941, 1.5 fold-change, p = 6.76x10^-22), 7: invasive ductal breast carcinoma (rank 613, 1.5-fold change, p = 2.71x10^-71), 8: invasive lobular breast carcinoma (rank 947, 1.3 fold-change, p = 3.64x10^-28), 9: medullary breast carcinoma (rank 400, 1.8 fold-change, p = 3.25x10^-12), 10: mucinous breast carcinoma (rank 1932, 1.4 fold-change, p = 7.41x10^-10) and 11: tubular breast carcinoma (rank 1253, 1.4 fold-change, p = 1.24x10^-17). …”

EtOH decreased ΔΨm in a subset of esophageal keratinocytes. by Prasanna M. Chandramouleeswaran (3176268)

Neudesin: a neuropeptide hormone decreased in subjects with polycystic ovary syndrome by Giray Bozkaya (8739405)

Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. by O’Llenecia S. Walker (8486163)

Exogenous IL-15 decreases the fraction but not the absolute number of CD25^High CD4⁺ T cells. by Tom L. Van Belle (306406)

Impairment of autophagy decreases trimethylation at H3K4 in human monocytes. by Kathrin Buffen (651914)

Maternal Hypoxia Decreases Capillary Supply and Increases Metabolic Inefficiency Leading to Divergence in Myocardial Oxygen Supply and Demand by David Hauton (341981)

“…Hearts of male offspring subjected to Maternal Hypoxia showed a 20% decrease in cardiac output (<i>P</i><0.05), despite recording a 2-fold increase in glucose oxidation (<i>P</i><0.01) and 2.5-fold increase (<i>P</i><0.01) in palmitate oxidation. …”

(R+S) and (R)-albuterol decrease NF-κB activity by Marcela A Ferrada (41716)

“…After transfection, (R)-albuterol (R), (S)-albuterol (S), or racemic albuterol (R+ S) were added to cells pre-activated with (ConA, 5 μg/ml) and (PMA, 100 ng/ml) (CP) and then treated with (R)-, (S)-, or (R+S)-albuterol (Fig. 6). …”

Mutational analysis of GBV-C 152–167 NS5A peptide. by Jinhua Xiang (93812)

“…HIV replication was significantly decreased in Jurkat cell lines expressing full-length NS5A (1–414), the 152–167 peptide, and the S158E mutant (*) compared to all other cell lines on days 5, 6, and 7 days post-infection (panel C). …”

Herceptin down-regulates HER2 receptors and decreases HER3 phosphorylation, but it does not decrease HER2 phosphorylation. by Merel Gijsen (234741)

Inhibition of the mitochondrial fission decreases mtROS production. by Dong Ma (584680)

Subjects:

TGF-β decreases LPL mRNA expression in macrophages by Scott A. Irvine (26973)

HSP90 inhibition by RGRN-305 decreased the gene expression of proinflammatory cytokines induced by SARS-CoV-2 S protein. by Hakim Ben Abdallah (14578241)

(R)-albuterol decreases cytokine protein levels in activated T cells by Marcela A Ferrada (41716)

“…</p><p></p> (R)-albuterol, (S)-albuterol or racemic albuterol (R + S) at a dose (10M) were added to T (EL-4) cells pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP). …”

(R)-albuterol decreases cytokine levels in activated murine splenocytes by Marcela A Ferrada (41716)

“…</p><p></p> (R)-albuterol (R), (S)-albuterol (S) or racemic albuterol (R + S) at a dose (10M) were added to murine splenocytes pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP), (Fig 3 A, B). …”

Intracellular K⁺ decreases during pectoral fin bud growth. by Xiaowen Jiang (8291814)

Rapamycin treatment significantly decreases induction of lytic KSHV proteins. by Lisa A. Nichols (357612)

Increased endodiastolic volume and decreased ejection fraction in GJB4-deficient zebrafish. by Ryuji Okamoto (614374)

IL-1Ra expressed by MSCs decreased Th17 differentiation. by Kijun Lee (4888660)