Synergistic effect of HDACi and EZH2i on schistosomula viability. by Letícia Anderson (2543926)

“…Significant decrease in viability when comparing GSK343 alone and GSK343 plus TSA was assessed with a two-way ANOVA statistical test; asterisks indicate <i>p</i>-value <i>≤</i> 0.001. …”

Comparison of Genetic Structure of Epixylic Liverwort <i>Crossocalyx hellerianus</i> between Central European and Fennoscandian Populations by Eva Holá (771613)

“…Large populations possessed less SGS, with individuals showing a pronounced decrease in kinship over 50 cm of distance. …”

Pyruvate Dehydrogenase Activity is Diminished and Phosphorylation Enhanced in Respiring Cardiac Mitochondria from Mice Fed High Dietary Fat. by Clair Crewe (467358)

“…<p>Cardiac mitochondria (0.25 mg/mL) were incubated with 100 µM pyruvate and 1.0 mM malate. At 2.0 min, state 3 respiration was initiated by the addition of 0.25 mM ADP. …”

Mutations in LUSH^F121 do not affect the sensitivity of OR67d neurons to cVA. by Carolina Gomez-Diaz (408669)

“…There are no statistically significant differences in cVA sensitivity due to genotype between all the transgenic lines tested (ANOVA, <i>p = </i>0.1183). There is a slightly significant decrease in cVA-sensitivity at 100% cVA stimulation for LUSH^F121W when compared to LUSH^wt (<i>p</i><0.05, Tukey's multiple comparison tests).…”

Involvement of calcium influx and intracellular stores in NH₄⁺/NH₃-induced calcium changes. by Nicole Haack (621328)

“…<p><b>(A)</b> Influence of combined removal of extracellular calcium with the NMDA-receptor blocker DLAP5 (“0Ca²⁺/100 µM DLAP5”; indicated by bar) on NH₄⁺/NH₃-induced calcium changes in a hippocampal astrocyte. …”

Supplementary Material for: Seasonal variations in stroke occurrence by Brissette V. (19023743)

“…Results During our study period, we observed 394,145 stroke or TIA events, with a decrease in monthly hospitalization/emergency department visits per 100,000 people between January 2003 and December 2017 from 24.22 to 17.43. …”

TSA inhibited EMC cells proliferation and downregulated miR-106b-93-25 cluster and its host gene MCM7. by Zhi-Ning Zhao (138018)

“…(<b>d</b>) qRT-PCR analysis of miR-106b, miR-93, miR-25 and their host gene MCM7 expression in ECC-1 and HEC-1A cells treated with TSA (100 ng/mL) for 24 h. …”

Effects of Hypericum perforatum on turning behavior in an animal model of Parkinson's disease by Débora Dalla Vecchia (7575491)

“…All tested doses significantly reduced the number of contralateral turns in all days of evaluation, suggesting a neuroprotective effect. However, they were not able to prevent the 6-OHDA-induced decrease of tyrosine hydroxylase expression in the lesioned striatum. …”

Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus by Eleni Kyriakou (2063644)

“…Celastrol-administered mice at 100 μg/kg decrease food consumption and body weight via a leptin-dependent mechanism, yet its molecular targets in this pathway remain elusive. …”

Table_1_How Difficult Was It? Metacognitive Judgments About Problems and Their Solutions After the Aha Moment.DOCX by Nadezhda V. Moroshkina (12904751)

“…experience after the presentation of the solution was associated with a decrease in subjective difficulty. When participants could not solve a problem but experienced the Aha! …”

CK2 inhibition in proliferating cells resulted in accelerated expression of differentiation markers. by Natalia González (362674)

“…(C) Quantification of cell subpopulations present in (B), shows a ~10-fold increase in the percentage of Pax7(-)/ myogenin (+) cells (i.e. differentiating cells) with a concomitant decrease in the percentage of proliferating Pax7(+)/myogenin(-) sub population. mean±SEM, n = 3. …”

Acute suppression of Ezh2 induces apoptosis in pOLs. by Falak Sher (151989)

“…</b> (<b>H</b>) Quantification of apoptotic (cleaved caspase 3-positive) and differentiating (RIP-positive) cells in Ezh2-shRNA treated and control (nc-shRNA) pOLs. Bar graphs represent mean of three independent experiments ± S.D. (Calibration bar in (<b>A</b>) represents 100 micrometers, which is valid for all the photomicrographs (<b>A</b>–<b>F</b>); ** in (<b>H</b>) represents p<0.01).…”

Diversity of <i>Listeria monocytogenes</i> Strains of Clinical and Food Chain Origins in Belgium between 1985 and 2014 by S. Bertrand (3207903)

“…Since 1985, we observed a significant decrease in incidence of the Materno-Neonatal cases (from 0.15 to 0.04 cases /100,000 inhabitants-year), which is probably to be attributed to active prevention campaigns targeting pregnant women. …”

Mode and mechanism of OGDHC inhibition. by Moustafa Elkalaf (441286)

“…<p><b>A.</b> TPMP causes mixed inhibition of OGDHC. Increasing the concentration of TPMP caused a decrease in the Vmax and an increase in Km. …”

Data_Sheet_1_Shared Species Analysis, Augmented by Stochasticity Analysis, Is More Effective Than Diversity Analysis in Detecting Variations in the Gut Microbiomes.PDF by Zhanshan (Sam) Ma (4370170)

“…The shared species analysis (SSA) is a computational technique that can discern changes of community composition by detecting the increase/decrease of shared species between two sets of microbiome samples, and it should be more sensitive than standard diversity analysis in discerning changes in microbiome structures. …”

Supplementary Material for: Analysis of Stroke Burden in China from 1990 to 2021 and Projections for the Next Decade by Li X. (3218241)

“…Results: Between 1990 and 2021, the age-standardized incidence rate (ASIR) of stroke in China decreased from 226.938 to 204.753 per 100,000, while the global ASIR decreased from 180.973 to 141.553 per 100,000. …”

Antireflective Paraboloidal Microlens Film for Boosting Power Conversion Efficiency of Solar Cells by Chaolong Fang (3610022)

“…Their surface morphology (aspect ratio and packed density) is vital to photon management in solar cells. Here, we report a 100% packed density paraboloidal microlens array (PMLA), with a large aspect ratio, fabricated by direct-write UV laser photolithography coupled with soft imprint lithography. …”

Effects of PP on the proliferation of liver cancer cell lines. by Wenwen Xu (175846)

“…</b> The colony-formation assay demonstrated a dose-dependent decrease in liver cancer cell proliferation (Huh7, Hep3B, HepG2 and SMMC-7721) when exposure to PP. …”

Impact of the naloxone standing order on trends in opioid fatal overdose: an ecological analysis by Michelle Taylor (1332300)

“…</p> <p><i>Results:</i> There was a significant decrease in the rate of fatal overdoses after the intervention: prescription opioid estimate number of deaths declined by .25 per 100,000 (<i>p</i> = .02), heroin estimate number of deaths declined by 1.83 per 100,000 (<i>p</i> < .001), fentanyl estimate number of deaths declined by 2.54 per 100,000 (<i>p</i> < .001). …”

Rapid Assessment of SARS-CoV‑2 Transmission Risk for Fecally Contaminated River Water by Jamie D. Shutler (8591496)

“…On the basis of in vitro data and using temperature as the primary controller of survival, we then demonstrate how viral loads likely decrease after a spill. These methods using readily available data suggest that sewage spills into rivers within countries with high infection rates could provide infectious doses of >40 copies per 100 mL of water. …”