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105841
Table_2_TP53 Mutational Status-Based Genomic Signature for Prognosis and Predicting Therapeutic Response in Pancreatic Cancer.XLS
Published 2021“…A five-gene TP53-associated signature was constructed in The Cancer Genome Atlas (TCGA) cohort by least absolute shrinkage and selection operator (LASSO)–Cox analysis and proven to be a robust prognostic predictor, which performed well in three independent Gene Expression Omnibus (GEO) validating cohorts. …”
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105842
Spatiotemporal analysis of canine rabies in El Salvador: Violence and poverty as social factors of canine rabies
Published 2018“…Violence had a negative association with rabies (RR = 0.663), which is likely due to reporting bias. …”
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105843
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105844
Image_1_TP53 Mutational Status-Based Genomic Signature for Prognosis and Predicting Therapeutic Response in Pancreatic Cancer.TIF
Published 2021“…A five-gene TP53-associated signature was constructed in The Cancer Genome Atlas (TCGA) cohort by least absolute shrinkage and selection operator (LASSO)–Cox analysis and proven to be a robust prognostic predictor, which performed well in three independent Gene Expression Omnibus (GEO) validating cohorts. …”
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105845
Data_Sheet_1_TP53 Mutational Status-Based Genomic Signature for Prognosis and Predicting Therapeutic Response in Pancreatic Cancer.docx
Published 2021“…A five-gene TP53-associated signature was constructed in The Cancer Genome Atlas (TCGA) cohort by least absolute shrinkage and selection operator (LASSO)–Cox analysis and proven to be a robust prognostic predictor, which performed well in three independent Gene Expression Omnibus (GEO) validating cohorts. …”
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105846
Table_4_TP53 Mutational Status-Based Genomic Signature for Prognosis and Predicting Therapeutic Response in Pancreatic Cancer.XLS
Published 2021“…A five-gene TP53-associated signature was constructed in The Cancer Genome Atlas (TCGA) cohort by least absolute shrinkage and selection operator (LASSO)–Cox analysis and proven to be a robust prognostic predictor, which performed well in three independent Gene Expression Omnibus (GEO) validating cohorts. …”
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105847
Image_2_TP53 Mutational Status-Based Genomic Signature for Prognosis and Predicting Therapeutic Response in Pancreatic Cancer.TIF
Published 2021“…A five-gene TP53-associated signature was constructed in The Cancer Genome Atlas (TCGA) cohort by least absolute shrinkage and selection operator (LASSO)–Cox analysis and proven to be a robust prognostic predictor, which performed well in three independent Gene Expression Omnibus (GEO) validating cohorts. …”
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105848
Blocking EGFR activation blocks neuroglian stabilization.
Published 2013“…<p>Control (DMSO) and PD168393-treated animals injected at early stage 5. A: Control – paraformaldehyde fixation and Triton permeabilization. …”
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105849
Average daily costs in Euro of inpatient treatment of patients with paranoid SZ (blue-green graphs) and SAD (red-yellow).
Published 2016“…Note that the number of averaged cases decreases over time. with less than 5 patients received longer treatments than 154 days (i.e. for 167, 180, 183 and 253 days respectively). …”
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105850
Nucleophilic Aromatic Substitution Reactions for the Synthesis of Ferrocenyl Aryl Ethers
Published 2016“…Their electrochemical investigations reveal a splitting of the two redox processes of the ferrocenyls that decreases from 155 mV (1,2-substitution) to 130 mV (1,3-substitution) on the basis of electrostatic interactions.…”
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105851
Image_1_Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue.tif
Published 2022“…Tissue targeting is accomplished through the binding of the fusion protein to complement C3 fragments that contain a surface-exposed C3d domain and which are covalently deposited on tissues where complement is being activated. To that end, we generated a fusion protein that contains an anti-C3d monoclonal antibody recombinantly linked to the first 10 consensus repeats of CR1 (CR1<sub>1-10</sub>) with the intention of delivering high local concentrations of this complement negative regulatory domain to tissue-bound complement C3 fragments iC3b, C3dg and C3d. …”
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105852
Image_2_Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue.tif
Published 2022“…Tissue targeting is accomplished through the binding of the fusion protein to complement C3 fragments that contain a surface-exposed C3d domain and which are covalently deposited on tissues where complement is being activated. To that end, we generated a fusion protein that contains an anti-C3d monoclonal antibody recombinantly linked to the first 10 consensus repeats of CR1 (CR1<sub>1-10</sub>) with the intention of delivering high local concentrations of this complement negative regulatory domain to tissue-bound complement C3 fragments iC3b, C3dg and C3d. …”
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105853
Table_1_Decoupling the Effects of the Amyloid Precursor Protein From Amyloid-β Plaques on Axonal Transport Dynamics in the Living Brain.pdf
Published 2019“…<p>Amyloid precursor protein (APP) is the precursor to Aβ plaques. The cytoplasmic domain of APP mediates attachment of vesicles to molecular motors for axonal transport. …”
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105854
Data_Sheet_1_Decoupling the Effects of the Amyloid Precursor Protein From Amyloid-β Plaques on Axonal Transport Dynamics in the Living Brain.pdf
Published 2019“…<p>Amyloid precursor protein (APP) is the precursor to Aβ plaques. The cytoplasmic domain of APP mediates attachment of vesicles to molecular motors for axonal transport. …”
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105855
Table1_Profile and potential role of novel metabolite biomarkers, especially indoleacrylic acid, in pathogenesis of neuromyelitis optica spectrum disorders.DOCX
Published 2023“…The CSF levels of phenylalanine and tyrosine showed a significant increase exactly during the relapse stage, and IA in the CSF was also increased markedly during the relapse and remission phases. …”
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105856
Growth and chlorophyll in noni seedlings irrigated with saline water in substrate with vermicompost
Published 2019“…Thus, this study aimed to evaluate the growth and chorophyll of noni (Morinda citrifolia L.) in response to the salinity of irrigation water in substrates with and without vermicompost. A completely randomized design in a 4 × 3 factorial scheme was used, corresponding to four levels of electrical conductivity of the irrigation water (0.5, 1.5, 3.0 and 4.5 dS m-1), in three soil substrates (without humus, with 33.33 and 66.66% of humus). …”
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105857
Menthol induces large depolarizing currents in TRPM8-transfected neurons.
Published 2009“…Non-transfected neurons did not respond to menthol but always responded with robust currents to KCl at the holding potential of −70 mV. (G) A non-transfected neuron recorded in whole-cell voltage clamp held at 0 mV during 15 s acute application of 100 µM menthol with 100 µM picrotoxin added during the last 5 s. …”
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105858
Productivity and mineral composition of common bean in response to fertilization with molybdenum and nickel
Published 2022“…The experiment was performed in 5 x 2 factorial with 5 doses of Ni (0; 15; 30; 45 and 60 g ha-1) and Mo (0 and 80 g ha-1) in a randomized block design, repeated four times. …”
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105859
The archaeal RNA chaperone TRAM0076 shapes the transcriptome and optimizes the growth of <i>Methanococcus maripaludis</i>
Published 2019“…TRAM0076 unfolded three representative 5′UTR structures <i>in vitro</i> and facilitated the <i>in vivo</i> expression of a mCherry reporter system fused to the 5′UTRs, thus behaving like a transcription anti-terminator. …”
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105860
BMP4 inhibits FGF target responses in midline cells and CPCs.
Published 2014“…<p>(<b>A,B,D,E</b>) RT-qPCR on dissociated E12.5 midline cells (A,B) or CPCs (D,E). …”