Showing 681 - 700 results of 104,327 for search '(( 100 ((mean decrease) OR (we decrease)) ) OR ( 5 ((nm decrease) OR (a decrease)) ))', query time: 1.53s Refine Results
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    Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity by Elizabeth S. Childress (2116453)

    Published 2017
    “…Sphingosine 1-phosphate (S1P) is a pleiotropic signaling molecule that interacts with its five G-protein coupled receptors (S1P<sub>1–5</sub>) to regulate cell growth and survival and has been implicated in a variety of diseases including cancer and sickle cell disease. …”
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    Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines. by Octavian Bucur (470431)

    Published 2013
    “…The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”
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    Sample selection flowchart. by Ronald López (18098572)

    Published 2024
    “…The LFAs were scored according to their relative importance using a decision-tree-based algorithm, with the mean decrease in Gini index as the scoring metric.…”
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    Supplementary Material for: Kidney and cardiovascular outcomes in older population with mildly to moderately decreased kidney function - A nationwide cohort study by Jeon J. (10323467)

    Published 2024
    “…Introduction: Although the prevalence of chronic kidney disease (CKD) is increasing in the aging population, the clinical relevance of the CKD definition (glomerular filtration rate [GFR] < 60 ml/min/1.73 m2) in older populations remains debatable. We investigated the clinical outcomes in older populations with mildly to moderately decreased GFR (45–59 ml/min/1.73 m2, CKD stage 3A). …”
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