Evaluation of HH target gene mRNA and protein expression following vismodegib treatment of canine OSA cell lines. by Vincent E. Baldanza (8781671)

“…<p>(A) The cell lines demonstrated variable decreases in some target genes at the transcript level with treatment at the determined IC₅₀ value when compared to vehicle control (DMSO) treatment. …”

Effects of Gβ5 and Gβ1 coexpression on agonist-induced receptor internalization. by J. Christopher Octeau (622081)

“…<p><b>A.</b> Quantification of the relative levels of transiently expressed cell surface D2R in HEK293 cells expressing D2R alone, D2R and Gβ1 or D2R and Gβ5, after treatment of with dopamine (50 µM for 45 min). …”

Reduction of LZTFL1 activity restores BBSome ciliary trafficking in BBS3 and BBS5 depleted cells. by Seongjin Seo (198289)

Histological sections and Mankin score of rabbit cartilages also showed OA change at 2 weeks. by Kohei Nishitani (526108)

“…<p>A) OA change such as fibrillation of the surface and decrease of safranin/O stainingwas detected from 2 weeks and deteriorated overtime. …”

ANALYSIS OF MASTER SWIMMERS’ SPORT PERFORMANCE FOR DIFFERENT FREESTYLE DISTANCES by André Geraldo Brauer Júnior (5311607)

“…<div><p>ABSTRACT The aim of this study was to analyze the decline rate of master swimmers’ world records compared to absolute world records, and sport performance decrease for both genders and different age groups (25 to 99 years old) in 50, 400 and 1500 meters freestyle swimming. …”

Knockdown of endogenous GpIbα in cancer cells reduces the frequencies of mitotic and cytokinesis defects, while overexpression of GpIbα in immortalized noncancer cells increases th... by Qian Wu (209382)

“…(B) Frequencies of mitotic and cytokinesis defects in HeLa cells were significantly decreased after GpIbα knockdown and enforced overexpression of a shRNA-resistant GpIbα (mGpIbα) restored most of the mitotic defects (n>100 cells per sample). …”

Downstream molecular effects of knockdown of the expression of 5-HT_1B and 5-HT_1D receptors, on invasion and proliferation biomarkers in PaCa cells. by Nilgun Gurbuz (623605)

“…(Upper panel) Cells were transfected with 50 nM of indicated siRNAs, and after 72 h, the total RNA was extracted and the transcript levels of 5-HT_1B and 5-HT_1D were determined by standard RT-PCR as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0105245#s2" target="_blank">Materials and Methods</a>. …”

Overexpression of Atp13a2 protects cells from manganese cytotoxicity. by Janet Ugolino (3359054)

“…(A) Representative Hoechst staining of HeLa cells after MnCl₂ treatment. Bar, 100 μm. (B) Quantification of cell death. Graph is representative of three independent experiments and data is shown as mean ±SDM. …”

<i>In vivo</i> H₂S treatment prevents O₂-induced arrested lung vascular growth. by Arul Vadivel (424484)

“…Arrows highlight vWF-positive vessels; scale bars represent 100 µm. B. Mean data quantifying the number of vWF positive vessels between groups. …”

CK2 inhibition in proliferating cells resulted in accelerated expression of differentiation markers. by Natalia González (362674)

“…(C) Quantification of cell subpopulations present in (B), shows a ~10-fold increase in the percentage of Pax7(-)/ myogenin (+) cells (i.e. differentiating cells) with a concomitant decrease in the percentage of proliferating Pax7(+)/myogenin(-) sub population. mean±SEM, n = 3. …”

Acute suppression of Ezh2 induces apoptosis in pOLs. by Falak Sher (151989)

“…</b> (<b>H</b>) Quantification of apoptotic (cleaved caspase 3-positive) and differentiating (RIP-positive) cells in Ezh2-shRNA treated and control (nc-shRNA) pOLs. Bar graphs represent mean of three independent experiments ± S.D. (Calibration bar in (<b>A</b>) represents 100 micrometers, which is valid for all the photomicrographs (<b>A</b>–<b>F</b>); ** in (<b>H</b>) represents p<0.01).…”

Mutations in LUSH^F121 do not affect the sensitivity of OR67d neurons to cVA. by Carolina Gomez-Diaz (408669)

“…There is a slightly significant decrease in cVA-sensitivity at 100% cVA stimulation for LUSH^F121W when compared to LUSH^wt (<i>p</i><0.05, Tukey's multiple comparison tests).…”

Random Lasing in ZnO Nanopowders Based on Multiphoton Absorption for Ultrafast Upconversion Application by Jiao Tian (583054)

“…This study reports ultraviolet picosecond random lasing (RL) based on multiphoton absorption in zinc oxide (ZnO) nanopowders with a mean size of ∼100 nm under femtosecond optical excitation. …”

Measured Physical Activity Age by Chirag Patel (12240839)

“…In the following, we trained a neural network to predict age from 115,456 one week-long 100Hz wrist accelerometer recordings from the UK Biobank (mean absolute error=3.7±0.2 years), using a variety of data structures to capture the complexity of real-world activity. …”

Ivermectin and albendazole withdrawal period in goat milk by Patrícia Silva Santos (6305066)

“…The amount of residues contained in themilk was decreasing in function of time. The mean daily rates of decrease of albendazole residues were 63.34%, 40.18 and 100.0%, from the 2ndto the 4thday, respectively; on the 3rdday after treatment, 50% of the samples showed concentrations ≥ 47.61 μg.mL–1, and on the 4thday, no sample had albendazole residue. …”

Glycosaminoglycan (GAG) production from cultured chondrocytes under different oxidative conditions by Kazuo Yudoh (8787)

“…Values are expressed as the mean ± standard deviation of nine donors (= 4 culture dishes per treatment group at each incubation period; *< 0.05, **< 0.01, versus control group at each incubation time). …”

PFMA-3 induced glutathione and lipid peroxidation production greater than XRT. by Francesca Buontempo (3532004)

“…Epifluorescence images at 100 × of magnification. <b>b)</b> Representative FcMeOH/SECM images in constant height mode of non irradiated (ctrl) and irradiated SK-Mel28 cells at 4 Gy by PFMA-3 and XRT. …”

Diverse antidepressants increase CDP-diacylglycerol production and phosphatidylinositide resynthesis in depression-relevant regions of the rat brain-4 by Kimberly R Tyeryar (59260)

“…</p><p></p> with indicated concentrations of neomycin, followed by addition of 100 μM fluoxetine (FLU) or 300 μM imipramine (IMI), desipramine (DES), paroxetine (PAR), maprotiline (MAP), or nomifensine (NOM). …”

Table 1_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx by Aling Tang (17523700)

VEGFR1 and VEGFR2 Involvement in Extracellular Galectin-1- and Galectin-3-Induced Angiogenesis by Nicky D'Haene (422477)