Cytosolic Ca²⁺ transients in isolated cardiac myocytes from AC6mut and control mice. by Mei Hua Gao (458915)

“…Time to 50% relaxation (tau) in the presence of isoproterenol was decreased in cardiac myocytes from AC6mut mice. …”

MGBG inhibited sOPN levels and gene expression in cultured human monocytes. by Xia Jin (170912)

“…<p>1 day cultured monocytes were collected for total RNA extraction and iOPN expression, and culture supernatants for OPN ELISA; quantitative real-time PCR was performed for OPN gene expression. iOPN expression was measured by flow cytometry. MGBG decreased OPN gene expression and sOPN level in a dose-dependent manner. …”

Fas2 interacting partner IgCAMs Fipi and Elff are required for imaginal disc development. by Luis Garcia-Alonso (152388)

“…Over-expression of elff (GOF) in MS1096/+; UAS-elff/+ individuals also caused a reduction in wing size. The double LOF condition for fipi and elff (UAS-CG15630 RNAi RRID: BDSC_42589 plus UAS-CG33543 RNAi RRID: VDRC_32576, Ri2+3), produced a stronger wing size reduction, which was suppressed in a background with a 50% EGFR dosage reduction (Ri2+3 Egfr/+). …”

Supplementary material: Evaluation of emerging NASH therapies: the impact of treatment efficacy profiles on long-term health outcomes by William Herring (18495130)

“…Hypothetical efficacy profiles were defined affecting resolution (100%-increase), fibrosis improvement (100% increase), or fibrosis worsening (50% decrease). <b>Results:</b> For the SoC, 10-year LRC rates increased with baseline fibrosis stage (F1: 3.0%; F2: 9.8%; F3: 27.2%; F4/CC: 64.9%). …”

Data_Sheet_1_Acidification and hypoxia drive physiological trade-offs in oysters and partial loss of nutrient cycling capacity in oyster holobiont.PDF by Deevesh Ashley Hemraj (15775310)

“…Introduction<p>Reef building oysters provide vast ecological benefits and ecosystem services. A large part of their role in driving ecological processes is mediated by the microbial communities that are associated with the oysters; together forming the oyster holobiont. …”

ER distension and lipid biogenesis in insulin-exposed RBL2H3. by William E. Greineisen (781966)

“…<i>Green</i>, > 2 fold increase in treated over controls; <i>gray</i>, no change; <i>red</i>, decrease to < 50% of control levels. <b>F. Relative abundance of eicosatrienoic, arachidonic and linoleic acid in ER from control and Insulin-FDI treated cells</b>. …”

Image_1_Lactose-Induced Chronic Diarrhea Results From Abnormal Luminal Microbial Fermentation and Disorder of Ion Transport in the Colon.TIF by Hong Xue (28736)

“…The concentrations of lactose, galactose and lactic acid of the cecal content were markedly increased (P < 0.01) and SCFA concentration was significantly decreased (P < 0.01). This was associated with depletion of the Lachnospiraceae NK4A136 group and Ruminococcaceae UCG-005 and increased relative abundance of Lactobacillus, escherichia-shigella and megamonas in the cecal microbiota. …”

Declining trend of <i>Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps)</i> mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine... by Sofonias K. Tessema (802681)

“…The frequency of triple <i>Pfdhfr</i> mutation decreased significantly from 50.8% (32/63) to 15.9% (10/63) (<i>P</i><0.001), while <i>Pfdhps</i> double mutation remained high and changed only marginally from 69.2% (45/65) to 55.4% (40/65) (<i>P</i> = 0.08). …”

Supplementary Material for: The Effects of Direct Oral Anticoagulants, Warfarin, Aspirin and Thienopyridine on the Performance of Immunochemical, Faecal, Occult Blood Tests by Niikura R. (5945336)

Downregulating lncRNA <i>CASC9</i> in SW620 xenograft tumor inhibits SW620 proliferation. by Heping Zhang (29038)

“…Black represents sh-NC and grey represents sh-<i>CASC9</i>-2 in histograms. (A)Growth curves of xenograft tumors were drawn respectively in 1, 2, 3, 4 weeks, and tumor volume was inhibited in the sh-<i>CASC9</i>-2 subset. …”

Genetic Regulation of α-Synuclein mRNA Expression in Various Human Brain Tissues by Colton Linnertz (258148)

Stabilization of the Skeletal Muscle Ryanodine Receptor Ion Channel-FKBP12 Complex by the 1,4-Benzothiazepine Derivative S107 by Yingwu Mei (102313)

“…SR vesicles enriched in RyR1 bound ∼48 [³H]S107 per RyR1 tetramer with EC₅₀ ∼52 µM and Hillslope ∼2. The effects of S107 and FKBP12 on RyR1 were examined under conditions that altered the redox state of RyR1. …”

Pre-existing CD4+ T cell immunity to non-cognate core epitopes drives the rapid production of isotype-switched, higher avidity antibodies against target antigens. by Thomas Hills (351639)

“…(f) The concentration of the chaotropic agent sodium thiocyanate required to decrease the anti-CSP ELISA signal by 50% was determined in serum from mice (n = 4) pre-vaccinated with either PBS or OVA_323-339 in TMG four weeks after vaccination with CSP(OVA_323-339) liposomes and compared with unpaired, two-tailed t tests.…”

Investigation of the Extraction Complexes of Light Lanthanides(III) with Bis(2,4,4-trimethylpentyl)dithiophosphinic Acid by EXAFS, IR, and MS in Comparison with the Americium(III)... by Tian Guoxin (2967663)

“…The coordination number of Ln(III) in the complexes is 8; the coordinated donor atoms are 7 sulfur atoms from 4 HBTMDTP molecules and 1 O atom from a hydrated water molecule. With the increase of the atomic number of Ln, the coordination bond lengths of Ln−O and Ln−S decrease in the complexes. …”

Data_Sheet_1_Lactose-Induced Chronic Diarrhea Results From Abnormal Luminal Microbial Fermentation and Disorder of Ion Transport in the Colon.PDF by Hong Xue (28736)

“…The concentrations of lactose, galactose and lactic acid of the cecal content were markedly increased (P < 0.01) and SCFA concentration was significantly decreased (P < 0.01). This was associated with depletion of the Lachnospiraceae NK4A136 group and Ruminococcaceae UCG-005 and increased relative abundance of Lactobacillus, escherichia-shigella and megamonas in the cecal microbiota. …”

Grid division diagram. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

Model calculation diagram. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

Grid independence verification. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

Digital Object.pdf by Jacquelyn Smith (2589058)

“…This water gets carried into a storm sewer system or dumps right into our watersheds. …”

Antiviral activity of ASN2 is independent of interferon production and NS1. by Mila Brum Ortigoza (168874)

“…<p>(A) Virus titers from A549 and VERO cells infected with influenza A/WSN/33 virus (MOI = 0.01) and treated with increasing concentrations of ASN2 (6.25–50 µM) for 48 hours. …”