Image1_Exome sequencing confirms the clinical diagnosis of both joubert syndrome and klinefelter syndrome with keratoconus in a han Chinese family.JPEG by Xinhe Fang (9281324)

“…Best corrected visual acuity (BCVA): 0.5 (−1.00DS/-5.00DC*29°) in the right eye, counting fingers/40 cm in the left eye. …”

Negative regulation of protein-coding genes suggests increased genomic auto-immunity of <i>D</i>. <i>simulans</i> alleles. by Luyang Wang (476973)

“…<p>(A) The number of genes whose expression levels are decreased/increased (>1.5 fold, blue/red) in the presence of each transgene as compared to the corresponding mutant. …”

Supplementary Material for: Minimal Change Disease and Focal Segmental Glomerulosclerosis are associated with good kidney prognosis and Thrombotic Microangiopathy with poor kidney... by Neves P.D.M.M. (20408168)

“…Most patients had decreased kidney function at diagnosis, 43.5% required dialysis upon diagnosis, 77.6% received immunosuppression, and 2/3 achieved a clinical remission. …”

Table1_Effectiveness of early heparin therapy on outcomes in critically ill patients with sepsis-induced coagulopathy.docx by Jia-Jia Huang (243641)

“…Further analysis showed that treatment with 6,250–13750 IU/day of unfractionated heparin associated with a decreased risk of intensive care unit mortality. …”

Table 1_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. MAFLD mice induced by a high-fat diet were treated with TFA at doses of 50 and 100 mg/kg. …”

Table 2_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. MAFLD mice induced by a high-fat diet were treated with TFA at doses of 50 and 100 mg/kg. …”

Table 1_Body mass index influences Antimüllerian Hormone and inhibin B in adult males.xls by Wen Zhou (49050)

“…A negative correlation between BMI and AMH (β: -0.15, 95%CI: -0.23 to -0.06, P<0.01) and INHB levels (β: -2.14, 95%CI: -2.98 to -1.31, P<0.0001) was observed, with these correlations remaining statistically significant (AMH: β: -0.12, 95%CI: -0.23 to -0.01, P<0.05; INHB: β: -1.50, 95%CI: -2.66 to -0.34, P<0.05) after adjusting for relevant confounders. …”

Supplementary Figure 1: Antibodies validated for routinely processed tissue unpredictably stain frozen tissue sections by Giorgio Cattoretti (568042)

“…Antigen retrieval (AR) was performed by placing the sections in a 800 ml glass container filled with the retrieval solutions (10 mM EDTA in Tris-buffer pH 8, Merck), irradiate in a household microwave oven at full speed for 8 min, followed by intermittent electromagnetic radiation to maintain constant boiling for 1min., 5 min. or 20 min., and cooling the sections to about 50Co before use. …”

Fig 10 - by Narasimha M. Beeraka (12189587)

“…BT-474 cells with cisplatin/oxaliplatin treatment: expression of FN3K, Nrf2, and Keap1 was not completely declined with cisplatin but NQO1, and HO-1 expression was mitigated at higher concentrations; interestingly, oxaliplatin downregulated the expression of FN3K and Nrf2 consequently mitigated expression of antioxidant proteins such as NQO1 and HO-1. 1-deoxy-1-morpholinofructose (DMF) (dissolved in 50% ethanol), a competitive inhibitor of FN3K, was used as a positive control which could only inhibit ∼10% of total FN3K activity but the FN3K expression was not decreased upon DMF treatment [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0283705#pone.0283705.ref012" target="_blank">12</a>]. …”

Methodology flow chart. by Sidra Aman Rana (14167473)

“…<div><p>Domestic water availability is intricately linked with a growing population, urbanization, and associated land use/land cover change (LULCC). …”

Phenotypic characterization of <i>CsIVP</i>-RNAi transgenic plants. by Shuangshuang Yan (798064)

“…Scale bars represent 2 cm in panels A, D–J, and P; 2 mm in panel K; 200 μm in panels L–O; 50 μm in panels L’–O’; and 100 μm in panels R–U. …”

Clinical Connections KG version 20240501 by Jennifer Hadlock (20465732)

“…<p dir="ltr">The <a href="https://github.com/NCATSTranslator/Translator-All/wiki/Multiomics-Clinical-Connections-KP" rel="noreferrer" target="_blank">Clinical Connections KG</a> is created and maintained by the <a href="https://github.com/NCATSTranslator/Translator-All/wiki/Multiomics-Provider" target="_blank">Multiomics Provider</a> team from the Institute for Systems Biology in Seattle, WA. …”

Data Sheet 1_OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the fe... by Huiyu Xu (12255545)

“…A two-parameter logistic curve allowed translation of ovarian reserve scores into an “endocrine age” and enabled individualized prediction of future milestones, such as diminished reserve with ovarian score of 50 and perimenopause, the lowest ovarian reserve score in our ART population. …”

Table 1_Association of magnesium depletion score with serum anti-aging protein Klotho in the middle-aged and older populations.docx by Zhijie Zhuang (17669958)

“…</p>Results<p>The weighted average serum Klotho concentrations decreased significantly across MDS groups (low: 864.50, middle: 805.67, high: 755.02 pg.…”

Image 4_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Supplementary file 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.docx by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

DataSheet1_Reduce the application of phosphorus fertilizer in peanut fields and improve its efficiency by using iron modified biochar to adsorb phosphorus recovery products.docx by Junxiao Zhang (421908)

“…After the fifth desorption and recycling process, the adsorption capacity of the biochar decreased to 24%. The peanut yield in the FeB-P1 treatment was 50.8% higher than that in the FeBP-P2 treatment. …”

Table_1_Higher adherence to the Dietary Approaches to Stop Hypertension (DASH Diet) is associated with lower greenhouse gases and land use from protein foods.DOCX by Nicole R. Kling (16327404)

“…Diets with the greatest adherence had around 25–50% lower GHG and land use from total protein foods than diets with the lowest adherence. …”

Image 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Image_1_Gonadotropin-Releasing Hormone Receptor-Targeted Near-Infrared Fluorescence Probe for Specific Recognition and Localization of Peritoneal Metastases of Ovarian Cancer.JPEG by Qiyu Liu (3961796)

“…The fluorescence signal of peritoneal metastases peaked in intensity at 2 h and maintained for up to 48 h. ICG also showed a weak signal in the tumor lesions due to the enhanced permeability and retention effect, but the intensity decreased quickly within 48 h.…”