DataSheet1_Dose Dependent Antimicrobial Cellular Cytotoxicity—Implications for ex vivo Diagnostics.docx by Ana Copaescu (10314533)

“…The PBMCs were stimulated for the investigated drugs at the previously published drug maximum concentration (Cmax), and concentrations 10- and 100-fold above.</p><p>Results: In a human immunodeficiency virus (HIV) negative and a positive rifampicin-associated DRESS with positive ex vivo IFN-γ ELISpot assay, use of 10- and 100-fold Cmax drug concentrations decreased spot forming units/million cells by 32–100%, and this corresponded to cell cytotoxicity of more than 40 and 20% using an LDH assay and 7-AAD cell viability staining, respectively. …”

DataSheet1_Dose Dependent Antimicrobial Cellular Cytotoxicity—Implications for ex vivo Diagnostics.docx by Ana Copaescu (10314533)

“…The PBMCs were stimulated for the investigated drugs at the previously published drug maximum concentration (Cmax), and concentrations 10- and 100-fold above.</p><p>Results: In a human immunodeficiency virus (HIV) negative and a positive rifampicin-associated DRESS with positive ex vivo IFN-γ ELISpot assay, use of 10- and 100-fold Cmax drug concentrations decreased spot forming units/million cells by 32–100%, and this corresponded to cell cytotoxicity of more than 40 and 20% using an LDH assay and 7-AAD cell viability staining, respectively. …”

DataSheet1_Dose Dependent Antimicrobial Cellular Cytotoxicity—Implications for ex vivo Diagnostics.docx by Ana Copaescu (10314533)

“…The PBMCs were stimulated for the investigated drugs at the previously published drug maximum concentration (Cmax), and concentrations 10- and 100-fold above.</p><p>Results: In a human immunodeficiency virus (HIV) negative and a positive rifampicin-associated DRESS with positive ex vivo IFN-γ ELISpot assay, use of 10- and 100-fold Cmax drug concentrations decreased spot forming units/million cells by 32–100%, and this corresponded to cell cytotoxicity of more than 40 and 20% using an LDH assay and 7-AAD cell viability staining, respectively. …”

Maturation of GABAergic synaptic and intrinsic properties in primary visual cortex. by Sandra J. Kuhlman (89333)

“…The average current from all trials in which a 350±50 pA EPSC was elicited is shown here. Young: n = 9 (of 14 cells) fulfilled this criteria, mature: n = 8 (of 13 cell) fulfilled this criteria. …”

PF16 gene deletion reduces male gamete flagellar motility and ookinete (zygote) formation. by Ursula Straschil (134248)

“…There was a decrease in the frequency of ookinete formation in both mutant clones when compared to wild type (WT). …”

Determining the molecular mechanism of the causal mutation. by Jessica Chang (461001)

“…(<b>D</b>) Chromatin immunoprecipitation data showing the difference in binding for Sok2 and Mot3 to the <i>ERG28</i> promoter in wildtype RM/RM AA112Δ. In both cases a significant decrease in binding is observed in RM AA112Δ.…”

Increased PrP accumulation upon FDCs through the course of early prion disease. by Pekka Kujala (79561)

“…The arrow in panel D indicates a desmosome. (F) Trypsin treatment of sections (white bar; scrapie +T) causes an average decrease of 84% in the amount of PrP-specific label on FDC plasma membranes of PrP-infected mice when compared to untreated sections (black bar; scrapie -T; 100%). …”

Effect of PRE-Herbicide Treatments on Weed Management, Cotton (<i>Gossypium Hirsutum</i> L.) Yield and Fiber Properties by Thomas Gitsopoulos (9769274)

“…However, other herbicides such as flurochloridone, flumioxazin and the premixture pendimethalin plus terbuthylazine are alternative pre-emergence options for weed control. A field experiment was conducted in northern Greece in 2021 and repeated in 2022 to study the effect of the preemergence mixtures fluometuron+ s-metolachlor at 1500 + 960 g a.i. ha⁻¹, flumioxazin+ s-metolachlor at 50 + 960 g a.i. ha⁻¹, flurochloridone+ s-metolachlor at 325 + 960 g a.i. ha⁻¹ and pendimethalin+ terbuthylazine at 1125 + 562.5 g a.i. ha⁻¹ on weed control, cotton yield and technological properties of cotton fiber. …”

Dataset Fits and Simulation by Calvin Hohn (20458484)

“…</p><p dir="ltr">Control experiments show that pepsin becomes active later in the process and causes</p><p dir="ltr">a final exponential decrease in particle area to a stable final value through proteolytic</p><p dir="ltr">degradation. …”

Erratum: Skeletal Muscle Metabolic Gene Expression Is Not Affected by Dichloroacetate-Mediated Modulation of Substrate Utilisation by Tisdale P.B. (4271998)

“…<i>Methods:</i> The PDC activator, dichloroacetate (DCA), was administered as an intravenous infusion in healthy male subjects at a rate of 50 mg kg^–1 min^–1, for 90 min. …”

Relationship between cold sensitivity and inhibitor sensitivity of primary HIV-1 envelope glycoproteins. by Hillel Haim (216672)

“…Data represent the mean incubation time on ice required for a 25% decrease from initial infectivity (IT25) in an experiment performed with three replicate samples. …”

Activation of caspases and mitochondria. by Michael Plötz (326888)

“…<p>(A) Processing of caspase-3, -8 and -9 is shown in Mel-2a cells at 24 h and at 48 h after transduction with AdV-AK (MOI=50). …”

Enrichment and stability of synaptoneurosomes. by Celia Williams (265997)

“…<p>Microscopy: A) Nuclear contamination of the homogenate (2 µl smears) (DAPI fluorescence) decreases after sequential passage through mesh screens with B) the post- 10 µm screen synaptoneurosome pellet (100 µl volume) still retaining a few nuclei (Bar = 20 µm). …”

RO5464466 blocked the production of progeny virus and inhibited an established influenza virus infection. by Lei Zhu (16642)

“…<p>(A) Decrease of progeny virus production in cells treated with RO5464466 and other reference compounds. 12-well plates were seeded with MDCK cells at a density of 1.5×10⁵ cells per well. …”

Data_Sheet_1_Artificial intelligence in healthcare: combining deep learning and Bayesian optimization to forecast COVID-19 confirmed cases.pdf by Areej Alhhazmi (6535361)

“…Based on simulation findings, it can decrease the DQN work cycle by roughly 28% and diminish data overhead by more than 50% on average.…”

GFP sensor assay. by Ana R. Soares (156281)

“…Co-injection of the M1 reporter with the miR-2188 duplex produced normal GFP levels, indicating that the BS-1 mutation abolished miR-2188 binding. On the other hand, a significant decrease in GFP expression was observed after co-injection of the M2 reporter with miR-2188, relative to the controls, indicating that BS-2 was not critical for miR-2188 binding. …”

Quantification of <i>in vivo</i> silica nanoparticle clearance. by Pascal Detampel (7444607)

“…<b>D:</b> Whole organ imaging. Overlay of a white light image of the organs and a heat map-display of the fluorescence in liver (top), spleen (middle), and kidney (bottom) 24 h after instillation of Ø 50 nm Cy-7-labelled silica particles into the lung (right). …”

Simulation Code by Calvin Hohn (20458484)

“…</p><p dir="ltr">Control experiments show that pepsin becomes active later in the process and causes</p><p dir="ltr">a final exponential decrease in particle area to a stable final value through proteolytic</p><p dir="ltr">degradation. …”

Pacing during an ultramarathon running event in hilly terrain by Hugo Kerhervé (618369)

“…</b> There were no significant differences in normality, variances or means in the relative speed in 173-km and 103-km participants. Relative speed decreased in LEV, UH and DH. The main component of speed loss occurred between 5% and 50% of the event distance in LEV, and between 5% and 95% in UH and DH. …”

MuSK patient IgG4 or IgG1-3 do not induce endocytosis of MuSK. by Inga Koneczny (481353)

“…(B) Staining was scored by two individuals as described in methods, and the scores were normalised to the score at 0 hours for each condition. A slight decrease in staining was observed for cells incubated at 37°C, and pre-fixed cells also showed this reduction. …”