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point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
d decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
100 d » 100 μ (Expand Search), 100 _ (Expand Search), 100 g (Expand Search)
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Expression of mediators of transcriptional network is decreased in neonatal rats after hyperoxic injury and upregulated with DEX.
Published 2017“…The same effect was detected for DEX10 under normoxia. <b>E)</b> There was a significant decrease for Prox1 mRNA expression under hyperoxia alone and with DEX1 and DEX5, but also a significant up-regulation with DEX10. …”
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1345
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1346
Decreased proliferation and increased apoptosis in <i>Mab21l2</i> mutant embryos.
Published 2012“…<i>N-myc</i> expression was reduced in the compact myocardium of <i>Mab21l2</i> mutants (P and Q) compared to WT embryos (N and O), especially in the dorsal region of the left ventricle (arrowheads). la, left atrium; lv, left ventricle; ra, right atrium; rv, right ventricle. Scale bars represent 100 µm (A, D, H, K) and 50 µm (N and P). (R) Quantitative RT-PCR for genes regulating cell proliferation and apoptosis (<i>N-myc</i>, <i>Id2</i>, <i>Cyclin D1</i>, <i>Cyclin D2</i>), marker genes of myocardial differentiation (<i>Anf</i>, <i>Chisel</i>, <i>Mlc2v</i>), genes essential for the development of the trabecular myocardium (<i>Erbb2</i>, <i>Erbb4</i>, <i>Bmp10</i>), genes essential for heart development (<i>Nkx2.5</i>, <i>Gata4</i>), and endocardial transcripts (<i>Flk1</i>, <i>Tie1</i>, <i>Tie2</i>) normalized to <i>Gapdh</i> expression using RNA from dissected hearts of E11.5 WT and <i>Mab21l2</i> mutant (−/−) embryos. …”
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The proportion of Treg decreases and the proportion of Th17 cells increases, but the absolute numbers of both are increased.
Published 2015“…<p><b>(A and B)</b> At the time of bile ductal obstruction, flow cytometry analysis showed that the percentage of Tregs decreased but Th17 increased in the liver of the RRV group compared to the saline group. …”
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Inhibitory effects of FIPI or VU0155072-2 “NOPT” in mouse mammary tumors following xenotransplantation of human breast cancer cells.
Published 2016“…<p>(<b>A-C</b>) SCID mice were xenotransplanted with human MDA-MB-231 breast cancer cells following implantation of Alzet pumps containing 2 different PLD-small molecule inhibitors of activity: 5-fluoro-2-indolyl des-chlorohalopemide (FIPI) or N- [2- (4- oxo- 1- phenyl- 1, 3, 8- triazaspiro[4, 5]dec- 8- yl)ethyl]- 2- naphthalenecarboxamide (VU0155072-2) [also referred to as “NOPT” [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0166553#pone.0166553.ref031" target="_blank">31</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0166553#pone.0166553.ref040" target="_blank">40</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0166553#pone.0166553.ref042" target="_blank">42</a>]]. …”
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Pannexin-1 hemichannel blockade by probenecid decreases dendritic morphology and process dynamics of retinal microglia.
Published 2011“…<p><b><i>A</i></b>. Microglial morphologic parameters of dendritic tree area, total dendritic length, and branch point number were significantly decreased by the application of probenecid (1mM), an antagonist of pannexin-1 hemichannels; (n = 46 cells). …”
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Positive modulation of mGluR5 decreases spine density in the nucleus accumbens but not in the dorsal striatum.
Published 2016“…<p>(A) Twenty-four hours after systemic administration, CDPPB (5–10 mg/kg, <i>n</i> = 18 animals) decreased dendritic spine density and frequency of small head diameter spines (0.2 μm bin) compared to vehicle control (<i>n</i> = 8) in the nucleus accumbens core. …”
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