Hormone therapy decreased β-amyloid load and improved cognitive performance in early middle-aged mice. by Amy Christensen (4062937)

PGRN deletion decreased the susceptibility to invasive <i>C</i>.<i>albicans</i> infection in mice. by Jiayu Liu (3951515)

Colony survival is decreased in UUC-enriched deletion mutants after exposure to oxidative stress-inducing agents. by Lauren Endres (765718)

“…Significant differences in colony formation and survival were determined using a Student <i>t</i>-test: UUC-enriched mutants versus wild type under similar treatment conditions (n = 5, *P < 0.002, **P < 0.001).…”

<i>GSK-3β</i> −/− embryos exhibit decreased osteogenic gene expression in the palatine bones. by Emily R. Nelson (247130)

“…Scale bars in higher magnification images (second and fourth) represent 100 µm. (D) qRT-PCR of e15.5 <i>GSK-3β</i> +/+ and −/− embryos. …”

Fluoxetine decreases TOPFlash firefly luciferase reporter activity. by Kentaro Miyamoto (123271)

HFD Developmentally Decreases B Lymphopoiesis: RT-PCR was performed on whole BM extracted from the femur. by Benjamin J. Adler (417336)

“…(c) Pax-5 expression, which represents an intermediate step in B lymphopoiesis did not appear reduced at 2D, but was significantly decreased subsequently. …”

Everolimus decreased EC inflammation via lowered IL-1β and IL-6 expression in ECs. by Zsolt Fejes (844136)

In the absence of chloride, two-fold decrease in [Na⁺]_e shifted GLT-1a E_rev by −28 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…Arrows show amplitudes and directions of E_rev shifts associated with decrease in [Na⁺]_e. <b>(D)</b> Average E_rev shifts at [Glu^-]_e geometric means of 37.5 and 600 μM are approximately equal when [Na⁺]_e was decreased from 102 to 51 mM. …”

HIF^C neutrophils have increased levels of apoptosis and necrosis and decreased endothelial attachment. by Kelly M. Shepardson (404375)

Blockage of p38MAPK signaling decreased the expression of IL-1α in primary PDAC cells. by Vegard Tjomsland (360809)

Administration of anti-DJ-1 antibody decreased the inflammatory cytokine expression and attenuated ischemic neuronal injury. by Koutarou Nakamura (10833014)

Riccardin D decreased proliferation and induced apoptosis in intestinal polyps. by Hui-Ping Liu (290636)

“…(C): The levels of caspase-9, caspase-3 and cleaved PARP in intestinal polyps were increased by Riccardin D (n = 3). (D): Bcl-2 was decreased and Bax was increased in intestinal polyps in Riccardin D-treated mice (n = 3).…”

PLCε depletion leads to decreased basal Rap1 activity, which drives monolayer leak. by Peter V. DiStefano (3111639)

Loss of Runx1 in <i>mdx</i> mice decreases muscle mass, muscle strength and lifespan. by Kfir Baruch Umansky (783699)

A647D mutation decreases I_Na of WT and P1332L when co-expressed. by Jie Liu (15128)

Neuronal cell cultures derived from embryos injected with APPb-MO had decreased neurite length. by Ping Song (169215)

“…The neurons from the embryos injected with 8 ng of APPb-MO showed a decrease in neurite length compared to neurons from the control embryos (un-injected). …”

Gap junction (GJ) communication decreases the proportion of cells exhibiting Ca²⁺ spikes. by Dharsan K. Soundarrajan (11632145)

Decreased E/I synapse ratio and loss of cortico-LA synaptic plasticity in the absence of coronin 1. by Rajesh Jayachandran (542641)

“…Scale bars, 100 pA and 20 ms. See <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001820#pbio.1001820.s018" target="_blank">Table S1</a> for additional statistics.…”

Effects of ATP and primer-template binding on RecA-UmuC cross-linking efficiency in pol V Mut. by Angela J. Gruber (712958)

“…<p>Western blot using an antibody to UmuC demonstrating increased UmuC-RecA cross-linking with increasing ATPγS concentration and decreasing UmuC-RecA cross-linking with increasing primer-template concentration in the presence of 500 μM ATPγS. pol V Mut was generated using RecA N113Bpa as described in Methods, with ATPγS and primer-template hairpin DNA added where indicated. …”

100P homozygous mice show overall decrease in proportions of PV-expressing cells in the P21 neocortex. by Malgorzata Borkowska (3166719)

“…<p>(<b>A, B</b>) Proportion of PV-expressing cells was significantly decreased in the 100P/100P mouse cortex without any loss in the total interneurons number. …”