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Administration of a Toll-Like Receptor 9 Agonist Decreases the Proviral Reservoir in Virologically Suppressed HIV-Infected Patients
Published 2013“…We observed a mean reduction in proviral DNA in the CPG group of 12.6% (95% CI: −23.6–0.0) following each immunization whereas proviral DNA in the placebo-adjuvant group remained largely unchanged (6.7% increase; 95% CI: −4.2–19.0 after each immunization, p = 0.02). …”
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Cycloheximide (CHX) treatment decreases production of rRNA transcripts by POLR1 and POLR3.
Published 2019“…<p>(A) DAOY cells were treated with CHX (100 μg/ml) for either 6 or 14 hours; for metabolic RNA labelling, 5-EU was added 2 hours before the sample collection. …”
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Long COVID prevalence decreases with vaccine uptake in the U.S.
Published 2023“…<p>(A) Prevalence in U.S. states and the U.S. exhibits a decreasing trend with respect to vaccine uptake, both in the population vaccinated with at least one dose (top) and two doses (bottom), with the largest gap between 100% vaccinated and 100% unvaccinated scenarios observed in the reference population of adults who had COVID-19. …”
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