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Frailty in Old Age Is Associated with Decreased Interleukin-12/23 Production in Response to Toll-Like Receptor Ligation
Published 2013“…In contrast, poor nutritional status and frailty in subjects >75 years were associated with decreased IL-12p70 and IL-23 production. By intracytoplasmic staining, we confirmed that production of IL-12/23p40 by conventional dendritic cells (DCs) upon TLR ligation was decreased in frail patients. …”
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RA increases S100β+ and decreases peripherin+ cell prevalence while EDN3 decreases S100β+ cell prevalence.
Published 2013“…(A) The proportion of S100β+ cells was enriched by RA and decreased in response to EDN3 (B) RA increased, and EDN3 decreased the fraction of proliferating S100β+ cells. …”
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Lytic reactivation stimuli decrease Oct-2 expression.
Published 2012“…The amount of Oct-2 protein expression was quantitated using ImageJ software and represented as a numerical value below the Oct-2 immunblot. The Oct-2 protein level in untreated cells infected with the control lentivirus was set at 100.…”
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