Image_9_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_7_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_2_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Potential miRNAs targeting PDE8A. by Thijs Booiman (185008)

“…#<p>Fold change in expression in which day 5 is compared to day 0; >1 is an increase and <1 is a decrease in expression.…”

High Serum Adiponectin Level Is a Risk Factor for Anemia in Japanese Men: A Prospective Observational Study of 1,029 Japanese Subjects by Kei Kohno (3383669)

“…Our study demonstrates, both clinically and epidemiologically, that a high serum adiponectin level decreases the amounts of erythroid-related variables and is a risk factor for anemia in Japanese men.…”

H₂O₂-induced mitochondrial size decrease is prevented by WY pre-treatment in hippocampal neurons. by Juan M. Zolezzi (586604)

The pro-inflammatory cytokines were mainly inhibited but anti-inflammatory genes were significantly activated in zebrafish embryos under PGRP5-KD conditions. by Xi Li (19208)

The mole fraction of arsenic acid (H₃As(V)O₄) species at pH 3.90 and pH 7.96, the minimum and maximum pH values observed in this study (Fig 8; Table 1) [23]. by Seth H. Frisbie (7821866)

The expression of Cregs is diminished in the allograft model with the progression of ATCMR. by Kazuaki Yamanaka (2541484)

“…Statistical significance was assessed by the t-test and Tukey’s HSD test. (A) qRT-PCR showed significantly diminished expression levels of Crry and CD59 mRNA in the allografts, compared to syngeneic grafts, at day 5 after transplantation. …”

Data_Sheet_1_Polydatin, A Glycoside of Resveratrol, Is Better Than Resveratrol in Alleviating Non-alcoholic Fatty Liver Disease in Mice Fed a High-Fructose Diet.docx by Guangshan Zhao (8828441)

Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A_2A and dopamine D₂ receptors for Parkinson's disease treatment - Fig 5 by Yi-Ming Shao (577266)

“…<p>Dose-response curves of compound <b>5</b> (A), compound <b>6</b> (B) and (±)-PPHT.HCl (C) in D₂R-proteopolymersomes-based fluorescence polarisation (FP) competition assay with BODIPY-NAPS. …”

Early maladaptive schemas in adult survivors of interpersonal trauma: foundations for a cognitive theory of psychopathology by Thanos Karatzias (8376780)

Electron micrographs (magnification of × 30,000) and polyP levels (AU, arbitrary units) of <i>L</i>. <i>rhamnosus</i> CRL 1505. by María A. Correa Deza (4097602)

Comparison between fitted model (solid lines) and data (markers) at the whole lung scale (a) and in the same three example grids as Fig 2b. by Monica E. Shapiro (22622240)

Temperature-Responsive Peptide–Nucleotide Coacervates by Tiemei Lu (4244926)

“…Both the enthalpic and entropic parts of this nonelectrostatic interaction decrease in the order G/A/U/C/T, in accordance with nucleobase stacking free energies. …”

Temperature-Responsive Peptide–Nucleotide Coacervates by Tiemei Lu (4244926)

“…Both the enthalpic and entropic parts of this nonelectrostatic interaction decrease in the order G/A/U/C/T, in accordance with nucleobase stacking free energies. …”

KYNA and zaprinast decrease the [Ca²⁺]i plateau phase following an IP3-mediated stimulus in mouse cortical astrocytes. by Rolando Berlinguer-Palmini (491113)

“…<p><b>A</b>) A typical example of KYNA and zaprinast-induced decrease in somatic fluo-3 fluorescence time course measured in three different astrocytes in cultures: control (<i>upper panels</i>), in the presence of 10 μM KYNA (<i>middle panels</i>) or zaprinast 1 µM (<i>lower panels</i>). …”

Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol expo... by Frederik Abel (8452101)

“…Hypoxia increased apoptosis of H9c2 cells (hypoxia: 8.4%±0.6; normoxia: 2.5%±0.1; p<0.0001). RIPC-EVs decreased H9c2 cell apoptosis compared to control (apoptotic ratio: 0.83; p = 0.0429) while Sham-EVs showed no protection (apoptotic ratio: 0.97). …”

Flow cytometry fluorescence density-plot analysis (Q₁ dead, Q₂ injured and Q₃ live cell population) of <i>L</i>. <i>rhamnosus</i> CRL 1505 grown in... by María A. Correa Deza (4097602)

Significant decrease in apoptosis was detected in the IL-1α or IL-1β deficient mice compared to WT mice after FHF induction. by Maya Sultan (2863391)