Image1_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

Image2_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

Image3_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV by Henryk Majczyński (830716)

“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT₂ (Cyproheptadine; Cypr), 5-HT_2A neutral antagonist (Volinanserin; Volin), 5-HT_2C neutral antagonist (SB 242084), and 5-HT_2B/2C inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”

Matrix crosslinking decreases cell migration persistence. by Michael Pamonag (12295175)

The decrease in blood flow disrupts CV pruning. by Lin Wen (557398)

Genotype frequencies of the polymorphisms <i>rs1799971</i> (OPRM1), <i>rs6296</i> (5-HT_1A) and the triallelic 5-HTT for the whole group, as well as fibromyalgia (FM) pat... by Jeanette Tour (10790855)

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

No effects of trehalose treatment in mitochondria length in HT fibroblasts. by Collin M. MacLeod (17512385)

Analysis of tumour vasculature with the addition of more HT groups. by Deepa Sharma (278210)

“…The vasculature becomes less evident in the treated groups, with decreasing numbers of stained blood vessels. Images were taken at a 20x objective lens, and the scale bar denotes ~50μm. …”

Serum samples and 50% NAI values. Serum samples taken from CEIRS study. by Harrison Powell (9040128)

The PRAME-AS knockout cells showed a decrease in migration, proliferation, stemness, and viability. by Zahra Hosseininia (22265113)

Normalized pressure pain thresholds (PPTs) (mean ± SEM) at start, middle, end and 5 minutes after a standardized tourniquet test. by Jeanette Tour (10790855)

IFNγ enhances the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> uptake by the human U-87 MG astroglioma cells. by Glaucia Vilar-Pereira (686134)

Fx treatment abrogates the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> infection of human U-87 MG astroglioma cells. by Glaucia Vilar-Pereira (686134)

The primers related to FAM50A. by Longhai Li (4052044)

“…Knockdown of FAM50A decreased cell proliferation ability, the proportion of EdU positive cells, and the number of CRC cell colonies, whereas overexpressing FAM50A promoted proliferative phenotypes. …”

THRα/β EC₅₀ values and selectivity of test compounds. by Xuan G. Luong (9761423)

Multiple logistic regression model exploring factors associated with >50% seizures reduction at month 4. by Michel Mandro (2637532)

A picture of the 50 L small-scale environmental chamber. by Eloise Parry-Nweye (7548998)