<i>SNAP-25</i> gene expression (copies/ng) in MO3.13 cells transfected with miR-23a-3p mimic, miR23a-3p inhibitor, miR-181a-5p mimic, miR-181a-5p inhibitor, and scramble negative m... by Simone Agostini (760354)

Nicotine decreased Wnt5a expressions in SK-BR-3 cells. by Masanori A. Murayama (5774585)

Decreased biofilm formation in the Δ<i>tad123</i> mutant cells. by Tra-My Duong-Nu (7300970)

Maximum concentrations (ng/L) of 88 pharmaceuticals detected at least once (in order of decreasing number of detections across all regions and samples) in water samples from wadeab... by Paul M. Bradley (523469)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Changes of anti-oxidative enzyme and oxidative stress after in a mouse model of kidney fibrosis. by Wencheng Jin (13136262)

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Repeated LSPC treatment prolongs survival of and decreases PrP^Res accumulation in a subset of prion-infected mice. by Heather Bender (363996)

Data_Sheet_1_Microclimatic Warming Leads to a Decrease in Species and Growth Form Diversity: Insights From a Tropical Alpine Grassland.PDF by Sisimac A. Duchicela (11503918)

“…We installed five monitoring blocks in 2012 at ca. 4,200 m asl with 20 OTCs and 50 control plots randomly distributed within each block. …”

Reference mutations versus background noise across replicates. by Lizhi Yu (12476136)

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Quantification and accuracy of average VAF. by Lizhi Yu (12476136)

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Analytical sensitivity and reproducibility. by Lizhi Yu (12476136)

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Depth of coverage and heterogeneity of the mutation loci. x-axis, mutation loci in sample set one or two; y-axis, depth of coverage after UMI consolidation. by Lizhi Yu (12476136)

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Impact of mutation type on VAF quantification performance. by Lizhi Yu (12476136)

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Schematic overview of the cross-platform study. by Lizhi Yu (12476136)

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Impact of DNA extraction process on depth of coverage. by Lizhi Yu (12476136)

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Evaluation of glucose consumption and lactate production in culture medium of HL-1 cells exposed to LG, NG, HG and IHG during 12 and 72h. by Patrick Mordel (17020879)

Claudin V is decreased following infection with Mtb. by Amanda S. Latham (12093638)

“…<p>Immunofluorescent staining of guinea pig brain tissue for DAPI (blue) and claudin V (cyan) in vessels was performed. Representative images of the frontal cortex (A–D), cerebral nuclei (F–I), brain stem (K–N), thalamus (P–S), and hippocampus (U–X) 15 days post-infection are shown. …”

Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis by Eric N. Ouattara (6890174)

“…<i>Immediate ART</i> increased the 5-year HIV care budget from $801.9M to $812.6M compared to <i>ART<350/μL</i>.…”

Time-adjusted survival curve for IL-6 and renalase among patients with COVID-19 disease (A) For composite outcome^a: High renalase + High IL-6; High renalase + Low IL-6;... by Basmah Safdar (12213257)