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we decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
100 we » 100 de (Expand Search)
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Development of a CRISPR/Cas-Based Detection Platform for Tracking Decreased Susceptibility to Cephalosporins in Neisseria gonorrheae
Published 2025“…Developing efficient and accurate detection of resistant strains is urgently needed for their management and treatment. We have developed the Multiplex Integrated RPA-CRISPR/Cas12a detection Assay (MIRCA) for simultaneous detection of Neisseria gonorrheae (<i>Ng</i>) and mutations with decreased susceptibility to cephalosporins. …”
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Data_Sheet_5_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.CSV
Published 2021“…We used untargeted metabolomics methods based on data generated with liquid chromatography-tandem mass spectrometry to identify, classify, and compare 13,480 unique foliar metabolites and to quantify the metabolomic similarity of species in each community with respect to the whole metabolome and each of five broad classes of metabolites. …”
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Hydroxymethylnitrofurazone (NFOH) decreases parasitaemia, parasitism and tissue lesion caused by infection with the Bolivia Trypanosoma cruzi type I strain in Swiss and C57BL/6 mic...
Published 2023“…In both experimental murine models, NFOH was able to reduce parasitemia blood avoiding parasitic reactivation, during immunosuppression period (dexamethasone 5mg/kg, 14 days), in 100% of the mice, and decrease tissue parasite nests, demonstrating absence of amastigote forms in all organs (100%) analyzed, data similar to benznidazole (BZN). …”
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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. The anti-mTNF conjugate <b>ADC5</b> fully inhibited inflammation in mouse contact hypersensitivity with minimal effects on corticosterone, a biomarker for systemic GRM effects, at doses up to and including 100 mg/kg. …”
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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. The anti-mTNF conjugate <b>ADC5</b> fully inhibited inflammation in mouse contact hypersensitivity with minimal effects on corticosterone, a biomarker for systemic GRM effects, at doses up to and including 100 mg/kg. …”
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Fig 5 -
Published 2024“…Plasma glucose, insulin, and glucagon were measured before, during, and after OGTTs up to 120 minutes post-prandially. We also assessed individual participants’ sweet taste responses to sucralose and their sensitivities to lactisole sweetness inhibition. …”
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Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg
Published 2023“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J<sub>H</sub><sup>-/-</sup>, λ5<sup>-/-</sup>, J<sub>H</sub><sup>-/-</sup> λ5<sup>-/-</sup>, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”
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Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg
Published 2022“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J<sub>H</sub><sup>-/-</sup>, λ5<sup>-/-</sup>, J<sub>H</sub><sup>-/-</sup> λ5<sup>-/-</sup>, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”
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Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg
Published 2023“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J<sub>H</sub><sup>-/-</sup>, λ5<sup>-/-</sup>, J<sub>H</sub><sup>-/-</sup> λ5<sup>-/-</sup>, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”
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Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg
Published 2022“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J<sub>H</sub><sup>-/-</sup>, λ5<sup>-/-</sup>, J<sub>H</sub><sup>-/-</sup> λ5<sup>-/-</sup>, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”
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Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg
Published 2023“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J<sub>H</sub><sup>-/-</sup>, λ5<sup>-/-</sup>, J<sub>H</sub><sup>-/-</sup> λ5<sup>-/-</sup>, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”