DataSheet_1_B Cell IL-4 Drives Th2 Responses In Vivo, Ameliorates Allograft Rejection, and Promotes Allergic Airway Disease.pdf by Zhixing Song (12236540)

“…In ovalbumin-induced allergic airway disease (AAD), B-IL-4/13 iKO mice had reduced inflammatory cells in BAL, and preserved lung histology with markedly decreased infiltration by IL-4⁺ and IL-5⁺ CD4⁺ T cells. …”

Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Image_3_Overexpression of the potato VQ31 enhances salt tolerance in Arabidopsis.jpeg by Mingming Zhai (602162)

“…The VQ protein core region contains a short FxxhVQxhTG amino acid motif sequence. In this study, the VQ31 protein from potato was cloned and functionally characterized. …”

Image_1_Sodium Butyrate Ameliorates Streptozotocin-Induced Type 1 Diabetes in Mice by Inhibiting the HMGB1 Expression.TIF by Yu Guo (102701)

“…High-mobility group box 1 protein (HMGB1) has been recognized as a potential immune mediator to enhance the development of T1D. …”

Table_2_Oral Supplementation of Lead-Intolerant Intestinal Microbes Protects Against Lead (Pb) Toxicity in Mice.docx by Qixiao Zhai (830803)

“…Supplementation with O. ruminantium significantly decreased Pb concentrations in blood (from 152.70 ± 25.62 μg/dL to 104.60 ± 29.85 μg/dL) and kidney (from 7.30 ± 1.08 μg/g to 5.64 ± 0.79 μg/g). …”

An adenylyl cyclase like-9 gene (<i>NlAC9</i>) influences growth and fecundity in the brown planthopper, <i>Nilaparvata lugens</i> (Stål) (Hemiptera: Delphacidae) by LinQuan Ge (4683439)

“…<div><p>The cAMP/PKA intracellular signaling pathway is launched by adenylyl cyclase (AC) conversion of adenosine triphosphate (ATP) to 3', 5'-cyclic AMP (cAMP) and cAMP-dependent activation of PKA. …”

Table2_Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells.xlsx by Fen Hu (342627)

“…Further, MA was observed to induce prostate cancer cell autophagy by increasing the expression of p53, p-p53, ULK1, Beclin1, Atg7, and Atg5 and the ratio of LC3-II/I and concurrently decreasing the expression of ERK1/2 and mTOR. …”

Presentation_1_Treatment of in vitro-Matured Bovine Oocytes With Tauroursodeoxycholic Acid Modulates the Oxidative Stress Signaling Pathway.pdf by Elisa Mariano Pioltine (10165832)

“…Interestingly, high concentration of TUDCA (1,000 μM) was toxic to oocytes, reducing the nuclear maturation rate, decreasing mitochondrial activity, and increasing the abundance of ER stress (HSPA5) and cellular apoptosis (CASP3 and CD40) related transcripts. …”

Image_1_Overexpression of the potato VQ31 enhances salt tolerance in Arabidopsis.jpeg by Mingming Zhai (602162)

“…The VQ protein core region contains a short FxxhVQxhTG amino acid motif sequence. In this study, the VQ31 protein from potato was cloned and functionally characterized. …”

DataSheet_1_Identification of gut dysbiosis in axial spondyloarthritis patients and improvement of experimental ankylosing spondyloarthritis by microbiome-derived butyrate with imm... by Hong Ki Min (9417766)

“…</p>Results<p>As a result, axSpA patients were found to have decreased α-diversity compared to HCs, indicating that axSpA patients have less diverse microbiomes. …”

Data_Sheet_1_Identifying genetic variants for amyloid β in subcortical vascular cognitive impairment.docx by Hang-Rai Kim (4689730)

“…</p>Results<p>We identified a novel SNP, rs4732728, which showed distinct associations with Aβ positivity in patients with SVCI (P_interaction = 1.49 × 10^–5); rs4732728 was associated with increased Aβ positivity in SVCI but decreased Aβ positivity in ADCI. …”

Image_1_Multimodal Evaluation of Neurovascular Functionality in Early Parkinson's Disease.TIFF by Maria Marcella Laganà (9302738)

“…The latter was accompanied by a decreased CBF (primary p_FWE = 0.037, lateral p_FWE = 0.014 VNs), while no GM atrophy was detected instead. …”

Table_1_Multimodal Evaluation of Neurovascular Functionality in Early Parkinson's Disease.DOCX by Maria Marcella Laganà (9302738)

“…The latter was accompanied by a decreased CBF (primary p_FWE = 0.037, lateral p_FWE = 0.014 VNs), while no GM atrophy was detected instead. …”

HRCT patterns and histology findings. by Konstantinos Samitas (2938953)

“…<p>(A) Patient 1: HRCT (pulmonary window) demonstrating diffuse ground glass opacities, small ill-defined centrilobular nodules, lobular areas of decreased attenuation (mosaic pattern) with a histological pattern consistent with hypersensitivity pneumonitis demonstrating poorly formed non-necrotizing granulomas (x20 and 40 respectively) and a definite diagnosis after MDT review of hypersensitivity pneumonitis. …”

Levels of total connexin 43 (Cx43) and phosphorylated connexin 43 (pCx43) were determined by enzyme-linked immunosorbent. by Natália F. Haddad (410503)

“…<p>AtT-20 cells were treated with lycopene (Licop) or beta-carotene (β-car) at concentrations of 5 and 10 µM for 48 and 96 h. Cx 43 levels decreased under carotenoid treatment at 48 h (<b>A</b>) and 96 h (<b>C</b>). …”

Image_1_Lipidomics profiles of human spermatozoa: insights into capacitation and acrosome reaction using UPLC-MS-based approach.pdf by Xiaohong Cheng (275970)

“…Moreover, 137 lipids had VIP values > 1.0 and twenty-two lipids had VIP > 1.5, based on the O2PLS-DA model. Furthermore, the identified twelve lipids encompassed increases in PI 44:10, LPS 20:4, LPA 20:5, and LPE 20:4, and decreases in 16-phenyl-tetranor-PGE2, PC 40:6, PS 35:4, PA 29:1, 20-carboxy-LTB4, and 2-oxo-4-methylthio-butanoic acid.…”

Data_Sheet_1_Sexual Dimorphisms of Protein-Coding Gene Profiles in Placentas From Women With Systemic Lupus Erythematosus.PDF by Hui-hui Li (12242504)

“…Among these 119 DEGs, five and zero are located on X- and Y-chromosomes, respectively, and four are located on the mitochondrial genome. …”

Circadian expression of the <i>Per1</i>::<i>luc</i> reporter gene in BMSCs. by Nathaniel Hassan (4373695)

“…<p>Femur-derived BMSCs were harvested from 3 male <i>Per1</i>::<i>luc</i> rats (5 months old). BMSCs from passages 3 to 5 were used for the experiments. …”

DataSheet_1_Lipidomics profiles of human spermatozoa: insights into capacitation and acrosome reaction using UPLC-MS-based approach.xlsx by Xiaohong Cheng (275970)

“…Moreover, 137 lipids had VIP values > 1.0 and twenty-two lipids had VIP > 1.5, based on the O2PLS-DA model. Furthermore, the identified twelve lipids encompassed increases in PI 44:10, LPS 20:4, LPA 20:5, and LPE 20:4, and decreases in 16-phenyl-tetranor-PGE2, PC 40:6, PS 35:4, PA 29:1, 20-carboxy-LTB4, and 2-oxo-4-methylthio-butanoic acid.…”

Novel Garnet-Structure Ca₂GdZr₂(AlO₄)₃:Ce³⁺ Phosphor and Its Structural Tuning of Optical Properties by Xinghong Gong (1782679)

“…The splitting of cubic crystal field energy level ²E_g in Ca₂REZr₂(AlO₄)₃:Ce³⁺ (CREZA:Ce³⁺) (RE = Lu, Y, and Gd) increases as the radius of RE³⁺ increases, and the splitting of ²E_g may dominate the difference of spectroscopic red-shift <i>D</i>(<i>A</i>) in CREZA:Ce³⁺. The splitting of the ²E_g in CaGd₂ZrSc­(AlO₄)₃:Ce³⁺ (CGZSA:Ce³⁺) phosphors increases seemly due to the decreasing of the covalent character of Ce–O. …”