Measurement of lysosome proteolytic and acidic functions in response to PIKfyve inhibition and ROS. by Golam T. Saffi (11747438)

“…<p>(A, B) RAW cells loaded with Alexa488-conjugated dextran to label lysosomes followed by treatment with vehicle, or 1 mM H₂O₂ for 40 min, or 1 μM rotenone for 60 min (A) or in combination with 20 nM apilimod for 40 min (B), and staining for lysosomal proteolytic function with Magic Red. …”

Deficiency of the UBE2C/F264 Axis Underlies Intrinsic Radioresistance in Cervical Carcinoma by Maowei Ni (15397932)

DataSheet_1_Single-Cell RNA Sequencing of Peripheral Blood Reveals Immune Cell Signatures in Alzheimer’s Disease.xlsx by Hui Xu (9203)

“…This study aimed to explore the molecular basis of peripheral immune cells and the features of adaptive immune repertoire at a single cell level. We profiled 36,849 peripheral blood mononuclear cells from AD patients with amyloid-positive status and normal controls with amyloid-negative status by 5’ single-cell transcriptome and immune repertoire sequencing using the cell ranger standard analysis procedure. …”

Diet Matters: Endotoxin in the Diet Impacts the Level of Allergic Sensitization in Germ-Free Mice by Martin Schwarzer (163105)

“…ST1 contained higher amount of bacterial DNA, approximately ten times more endotoxin, and induced higher, TLR4-dependent, cytokine production in dendritic cells compared to R03. In a germ-free mouse model of sensitization to the major birch pollen allergen Bet v 1, feeding on ST1 for at least two generations was associated with decreased production of allergen-specific IgE and IgG1 antibodies in sera in comparison to R03. …”

Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg by Wenqiao Jia (12356306)

“…</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca²⁺/CAMKK2/AMPK/AR signaling axis.…”

DataSheet_1_Importance of the choice of heat flux parameterization in regional air–sea coupled simulations: Case studies of marine heatwaves induced by atmospheric heatwaves in 199... by Taek-Bum Jeong (14103864)

“…<p>This study investigated the marine heat wave events (MHWs) that occurred near the Korean Peninsula during the summer of 1994 and 2018, using a regional air–sea coupled model. We analyzed the fifth-generation reanalysis data, ERA5, published by the European Centre for Medium-Range Weather Forecasts for both events. …”

DataSheet1_Integratively Genomic Analysis Reveals the Prognostic and Immunological Characteristics of Pyroptosis and Ferroptosis in Pancreatic Cancer for Precision Immunotherapy.PD... by Ting Yu (156230)

“…A high P-F score was associated with active immune phenotype, decreased genomic alterations, and significantly longer survival. …”

DataSheet_2_Single-Cell RNA Sequencing of Peripheral Blood Reveals Immune Cell Signatures in Alzheimer’s Disease.xlsx by Hui Xu (9203)

“…This study aimed to explore the molecular basis of peripheral immune cells and the features of adaptive immune repertoire at a single cell level. We profiled 36,849 peripheral blood mononuclear cells from AD patients with amyloid-positive status and normal controls with amyloid-negative status by 5’ single-cell transcriptome and immune repertoire sequencing using the cell ranger standard analysis procedure. …”

Table_3_The Age-Related Perfusion Pattern Measured With Arterial Spin Labeling MRI in Healthy Subjects.DOCX by Nan Zhang (46264)

“…</p><p>Methods: 50 healthy subjects (mean age 45.8 ± 18.5 years, range 21–85) had 3D structural MRI and pseudo-continuous ASL MRI at resting state. …”

Figure 3 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer by Ya-Yun Cheng (21751407)

“…<b>D,</b> Densitometry quantification of VIM and N-cadherin expression from five independent immunoblot experiments [<i>n</i> = 5; one-way ANOVA <i>P</i> = 0.0115 (MPZL3), <i>P</i> = 0.0065 (N-cadherin), <i>P</i> = 0.0025 (VIM); Dunnett multiple comparison test <i>P</i> values shown]. …”

Table_2_Association of sleep behaviors, insulin resistance surrogates, and the risk of hypertension in Chinese adults with type 2 diabetes mellitus.xlsx by Xuelin Yao (1841680)

“…Midday napping (1–30 min) is associated with a decreased risk of hypertension in patients with T2DM.…”

Table 1_Genome-wide identification of the COBRA-like gene family and expression pattern analysis under abiotic stresses of Sorghum bicolor (L.).xlsx by Shipeng Liu (800573)

“…</p>Methods<p>This study used a bioinformatics approach to characterize the CBL family genes in Sorghum bicolor (S. bicolor) at the genome-wide level to investigate their potential functions in S. bicolor development.…”

siRNA for Hes-1 inhibited proliferation of IEC-6 cells. by Guoqing Chen (427510)

“…Inhibition of Jagged-2 with siRNA was carried out as mentioned above (see the Materials and Methods). <i>A</i>: After 48 h of culture, protein was extracted from IEC-6 cells. …”

Image_7_Physiological and molecular mechanisms of the response of roots of Pinus massoniana Lamb. to low-temperature stress.jpg by Jingyu Lu (621174)

“…BAM, 4CL, CCoAOMT, PRX5, WRKYs, and hormone synthesis related genes play important roles. …”

The effects of the test compounds on tumor inhibition in LSC-xenografted zebrafish. by Beibei Zhang (509356)

“…<p>(A) Typical images of xenotransplanted zebrafish either not treated or treated with the control drug (imatinib) or an LSC inhibitor (parthenolide). …”

Table_3_Integrating Mortality Risk and the Adaptiveness of Hibernation.docx by Théo Constant (9109544)

“…Hibernation is considered a seasonal adaptation to prolonged periods of food shortage and cold. …”

DataSheet_1_Proteomic and metabolomic analysis of GH deficiency-induced NAFLD in hypopituitarism: insights into oxidative stress.docx by Yuwen Zhang (159537)

“…An enhanced regulation of peroxisome β-oxidation and ω-oxidation, together with a decreased NADPH regeneration, may exacerbate oxidative stress. …”

Presentation_1_An Analytical Model for Estimating Alveolar Wall Elastic Moduli From Lung Tissue Uniaxial Stress-Strain Curves.pdf by Samer Bou Jawde (8489046)

“…The stress-strain curves predicted by the model were comparable to curves generated by a previously published numerical alveolar network model. …”

Table_3_Association of sleep behaviors, insulin resistance surrogates, and the risk of hypertension in Chinese adults with type 2 diabetes mellitus.xlsx by Xuelin Yao (1841680)

“…Midday napping (1–30 min) is associated with a decreased risk of hypertension in patients with T2DM.…”

File S1 - Abnormal Interactions between Perifollicular Mast Cells and CD8+ T-Cells May Contribute to the Pathogenesis of Alopecia Areata by Marta Bertolini (564966)

“…TGFβ1 immunoreactivity is decreased in the HF ORS of AA patients. Figure S5. …”