DataSheet7_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Data Sheet 1_Trends in sepsis-associated cardiovascular disease mortality in the United States, 1999 to 2022.pdf by Malik Salman (20401364)

“…Sepsis-associated CVD mortality decreased between 1999 and 2013, from AAMR of 65.7 in 1999 to 58.8 in 2013 (APC −1.06*%, 95% CI: −2.12% to −0.26%), then rose to 74.3 in 2022 (APC 3.23*%, 95% CI: 2.18%–5.40%). …”

Table_2_Transcriptome in Combination Proteome Unveils the Phenylpropane Pathway Involved in Garlic (Allium sativum) Greening.XLSX by Jinxiang Wu (475283)

“…The greening phenomenon of garlic severely decreases the quality of garlic and hinders garlic processing. …”

Table_2_Initial Invasive or Conservative Strategy in Heart Failure With Preserved Ejection Fraction and Coronary Artery Disease.docx by Jun Gu (89637)

“…With a follow-up of 5 years, 378 (57.3%) in the invasive-strategy group and 403 (61.1%) in the conservative-strategy group reached the primary endpoint, and there was no significant difference in the rate of the primary endpoint (P = 0.162). …”

Erythrocyte-binding assay on transfected COS7 cells expressing different regions of PfRH1 before and after enzymatic treatment. by Xiaohong Gao (50514)

“…<p>(A) Chimeric constructs for the expression of different regions of <i>PfRH1</i> in 3D7. 3D7 clone <i>RH1</i> DNA sequence (Genbank accession no: AF533700) with intro spliced out includes signal sequence (SS, black) and Exon2 (grey) encoding a large extracellular domain and excludes transmembrane domain and cytoplastic tail. …”

Image 3_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Data_Sheet_1_Individual strategies in the rat gambling task are related to voluntary alcohol intake, but not sexual behavior, and can be modulated by naltrexone.docx by Nikita Tjernström (14049096)

“…Introduction<p>Gambling disorder (GD) is the first non-substance or behavioral addiction to be included in substance-related and addictive disorders in DSM-5. Since GD is a younger phenomenon relative to alcohol and substance use disorders, little is known about potential unique features in GD and to what extent characteristics are shared with alcohol and substance use disorders. …”

Amino Acid Oxidation of <i>Candida antarctica</i> Lipase B Studied by Molecular Dynamics Simulations and Site-Directed Mutagenesis by Mehdi Irani (1990660)

“…Molecular dynamics simulations have been performed on lipase B from <i>Candida antarctica</i> (CalB) in its native form and with one or two oxidized residues, either methionine oxidized to methionine sulfoxide, tryptophan oxidized to 5-hydroxytryptophan, or cystine oxidized to a pair of cysteic acid residues. …”

Superhydrophobic ZIF-8-Based Dual-Layer Coating for Enhanced Corrosion Protection of Mg Alloy by Xingxing Yin (7919447)

“…Moreover, the superhydrophobic ZIF-8-based coating could still retain excellent anticorrosion property after immersion in 3.5 wt % NaCl solution for 7 days. The enhanced anticorrosion ability was ascribed to the fact that a synergistic effect of the underlying LDH transition layer hindered the transmission of aggressive ions and the top superhydrophobic ZIF-8-based coating decreased the contact area of the substrate with corrosive solution. …”

The influence of nest location and the effect of predator removal on Cape Gannet <i>Morus capensis</i> egg predation by Kelp Gulls <i>Larus dominicanus vetula</i> by Zanri Strydom (13272821)

“…The peripheral nests saw a higher level of egg loss (average 1.5 eggs per week) compared with the central nests (average 1 egg per week). …”

Table_1_Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients.DOC by Maximilianos Elkouris (175800)

“…Simultaneously, SNCA mRNA levels are increased in the nigra, while LRRK2 and PINK1 mRNA levels are decreased both in the nigra and the cerebellum of PD subjects compared to controls, indicating a possible correlation between the expression profile of the respective lncRNAs with their adjacent coding genes. …”

<i>C. elegans</i> RNAi screen identifies conserved SMN modifier genes. by Maria Dimitriadi (238530)

“…<p>A) Four genes were identified as modifiers of <i>Cesmn-1(lf)</i> growth defects in the <i>C. elegans</i> RNAi screen: <i>ncbp-2</i>, <i>T02G5.3</i>, <i>grk-2</i> and <i>flp-4</i>. …”

Image_4_D-Serine Contributes to Seizure Development via ERK Signaling.tif by Tie Ma (6505097)

“…L-aspartic acid β-hydroxamate (LaaβH), an inhibitor of SR, significantly prolonged the latencies of seizures, shortened the durations of seizures, and decreased the total EEG power in rats. In contrast, D-amino acid oxidase inhibitor 5-chlorobenzo[d]isoxazol-3-ol (CBIO), which can increase D-serine levels, showed the opposite effects. …”

DataSheet_1_Real-Time Flash Glucose Monitoring Had Better Effects on Daily Glycemic Control Compared With Retrospective Flash Glucose Monitoring in Patients With Type 2 Diabetes on... by Reng-na Yan (5183327)

“…HbA1c decreased in both groups (both p < 0.01). Real-time FGMs increased daily exercise time compared with the retrospective group (p = 0.002).…”

Image_1_Regulation of miR-1-Mediated Connexin 43 Expression and Cell Proliferation in Dental Epithelial Cells.pdf by Tomoaki Nakamura (1714834)

“…This study aimed to analyze the expression of miRNAs produced during tooth development using a microarray system to clarify the role of miRNAs in dental development. miR-1 showed a unique expression pattern in the developing tooth. miR-1 expression in the tooth germ peaked on embryonic day 16.5, decreasing gradually on postnatal days 1 and 3. …”

Table 1_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Cumberpatch ZA, Finch E, Kane IA, et al., Basin Research, 2021. Movies of model evolution by Emma Finch (10685244)

“…Six experiments are shown: a baseline zero sedimentation model (M1) and five models with variable sedimentation rates and patterns, slow (M2), intermediate (M3) and fast (M4) rates. …”

Table_7_Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring.XLSX by Lisa J. Martin (228675)

“…Perinatal HP/LC and LP/HC exposures resulted in a decreased ability to clear glucose in the offspring, with reduced baseline insulin and glucose concentrations in the LP/HC group and a reduced insulin response post-glucose challenge in the HP/LC group. …”

The Role of Angiotensin II and Cyclic AMP in Alveolar Active Sodium Transport by Reem Ismael-Badarneh (3213921)

“…The rate of alveolar fluid clearance in control rats was 8.6% ± 0.1 clearance of the initial volume and decreased by 22.5%, 28.6%, 41.6%, 48.7% and 39% in rats treated with 10^-10 M, 10^-9 M, 10^-8 M, 10^-7 M or 10^-6 M of Ang II respectively (P < 0.003). …”

Serum 25-Hydroxyvitamin D Levels and Dry Eye Syndrome: Differential Effects of Vitamin D on Ocular Diseases by Donghyun Jee (480337)

“…</p><p>Results</p><p>The odds of DES non-significantly decreased as the quintiles of serum 25-hydroxyvitamin D levels increased (quintile 5 versus 1, OR = 0.85, 95%CI: 0.55–1.30, P for trend = 0.076) after adjusting for potential confounders including age, sex, hypertension, diabetes, smoking status, and sunlight exposure times. …”