Impact of Interleukin-6 –174 G>C Gene Promoter Polymorphism on Neuroblastoma by Francesca Totaro (474776)

“…</p><p>Conclusions</p><p>The biological effect of SNP <i>IL-6</i>–174 G>C in relation to promotion of cancer progression is consistent with the observed decreased survival time. The present study suggests that SNP <i>IL-6</i>–174 G>C may be a useful marker for NB prognosis.…”

Parallel, High-Quality Proteomic and Targeted Metabolomic Quantification Using Laser Capture Microdissected Tissues by Shichen Shen (1392565)

“…The strategy features: (i) an optimized molecular weight cutoff (MWCO) filter-based separation of proteins and small-molecule fractions with high and consistent recoveries; (ii) microscale derivatization and charge-based enrichment for ultrasensitive quantification of key androgens (LOQ = 5 fg/1k cells) with excellent accuracy/precision; (iii) reproducible/precise proteomics quantification with low-missing-data using a detergent-cocktail-based sample preparation and an IonStar pipeline for reproducible and precise protein quantification with excellent data quality. …”

Table1_Benchmarking microbial DNA enrichment protocols from human intestinal biopsies.XLSX by Dmitrij Marchukov (15356863)

“…However, ONT AS resulted in relevant shifts in the observed bacterial abundance, including 2 to 5 times more Escherichia coli reads. Furthermore, a modest enrichment of Bacteroides fragilis and Bacteroides thetaiotaomicron was also observed with AS. …”

Protective effects of <i>Bacillus</i> probiotics against high-fat diet-induced metabolic disorders in mice by Bobae Kim (3332823)

“…In this study, we demonstrate that a probiotic mixture composed of 5 different <i>Bacillus</i> spp. protects mice from high-fat diet (HFD)-induced obesity, insulin resistance and non-alcoholic fatty liver disease (NAFLD). …”

Data Sheet 1_The relationship between inflammatory factors and heart failure: evidence based on bidirectional Mendelian randomization analysis.zip by Xuanchun Huang (17359851)

“…Reverse Mendelian randomization suggested that the onset of heart failure might potentially influence the levels of four inflammatory factors, with ARTN and FGF5 decreasing after the onset of heart failure, and SLAM and MMP-10 increasing. …”

Presentation1_Cinnamomum zeylanicum Extract and its Bioactive Component Cinnamaldehyde Show Anti-Tumor Effects via Inhibition of Multiple Cellular Pathways.ppt by Sadhna Aggarwal (12718319)

“…The cancer cells showed a decreased expression of various PI3k-AKT-mTOR pathways related to VEGF, COX-2, Bcl-2, NF-κB, and proteins post-treatment.…”

Parameter Settings. by Yutong Liu (4027994)

“…The average edit distance decreases from 3.2 to 2.5, the BLEU score increases from 0.65 to 0.72, and the average processing time is reduced from 2.3 seconds to 1.8 seconds. …”

Image_1_Aberrant expression of bone morphogenetic proteins in the disease progression and metastasis of breast cancer.tif by Ming Liu (105953)

“…BMPs also play dual roles in tumour growth and metastasis of BC.</p>Conclusion<p>A shift pattern of BMPs was showed in different subtypes of breast cancer suggesting a subtype specific involvement. …”

DataSheet_1_Single-Cell RNA Sequencing Reveals the Immunological Profiles of Renal Allograft Rejection in Mice.pdf by Qixia Shen (11170275)

“…Both B cells and neutrophils decreased by about 3 folds. On the contrary, the proportion of macrophages and dendritic cells (DCs) increased significantly, especially by about a 4.5-fold increase in Ly6c^loMrc1⁺ macrophages and 2.6 folds increase in Ly6c^loEar2⁺ macrophages. …”

Data_Sheet_1_The Temporal Dynamics of EEG Microstate Reveals the Neuromodulation Effect of Acupuncture With Deqi.pdf by Xiaopeng Si (11276703)

“…Results showed that: (1) compared with tactile controls, acupuncture manipulation caused significantly increased deqi behavioral scores. (2) Acupuncture manipulation significantly increased the duration, occurrence, and contribution parameters of microstate C, whereas it decreased those parameters of microstate D. (3) Microstate C’s duration parameter showed a significantly positive correlation with acupuncture deqi behavior scores. (4) Acupuncture manipulation significantly increased the transition probabilities with microstate C as node, whereas it reduced the transition probabilities with microstate D as node. (5) Microstate B→C’s transition probability also showed a significantly positive correlation with acupuncture deqi behavior scores. …”

Comparison with Advanced Models. by Yutong Liu (4027994)

“…The average edit distance decreases from 3.2 to 2.5, the BLEU score increases from 0.65 to 0.72, and the average processing time is reduced from 2.3 seconds to 1.8 seconds. …”

Table_1_Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.xlsx by Georgia Papapavlou Lingehed (13174338)

“…Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3^rd trimester, followed by a transient exacerbation after delivery. …”

Data Sheet 1_Effects of low-temperature stress during rice heading stage on carbon and nitrogen allocation in paddy eco-system of northeastern China.docx by Tao Sun (91038)

“…</p>Results and Discussion<p>Low-temperature stress significantly reduced rice grain yield of JN809 (sensitive to low-temperature stress) and J88 (tolerant to low-temperature stress) varieties by 27.6% and 21.4%, respectively, This stress tendency increased C and N accumulation in rice stems and leaves, while concurrently decreasing C and N accumulation in panicles. Specifically, under low-temperature stress, the ¹³C isotope content in stems and leaves was found to be 14.0% and 19.0% higher than in the control treatment, while the ¹³C and ¹⁵N isotope contents in their panicles were 29.3% and 22.5% lower, respectively. …”

S1 Dataset - by Tzu-Hui Pao (8504268)

“…The patients with a baseline LN volume > 7.7 ml had a significantly worse median OS compared to those with smaller LN volume (18.8 vs. 46.9 months, p = 0.049), as did those with tumor regression grade (TRG) 3–5 after CCRT (13.9 vs. 86.7 months, p < 0.001). …”

Image3_Integrative analysis of the role of BOLA2B in human pan-cancer.TIF by Mingxing Liang (11361621)

“…Post-transcriptional modifications, including m5C, m1A, and m6A, were observed to regulate BOLA2B expression in all cancers. …”

Intragenic <i>ERG</i> Deletions Do Not Explain the Biology of <i>ERG</i>-Related Acute Lymphoblastic Leukemia by Eliska Potuckova (525220)

“…They represent the only genetic lesion described so far present in the majority of cases clustering into a subgroup of B-other subtype characterized by a unique gene expression profile, probably sharing a common, however, not yet fully described, biological background. …”

Table3_Benchmarking microbial DNA enrichment protocols from human intestinal biopsies.XLSX by Dmitrij Marchukov (15356863)

“…However, ONT AS resulted in relevant shifts in the observed bacterial abundance, including 2 to 5 times more Escherichia coli reads. Furthermore, a modest enrichment of Bacteroides fragilis and Bacteroides thetaiotaomicron was also observed with AS. …”

Data_Sheet_2_Phylogeographic Assessment Reveals Geographic Sources of HIV-1 Dissemination Among Men Who Have Sex With Men in Kenya.docx by George M. Nduva (12216416)

“…Maximum-likelihood (ML) phylogenetics and Bayesian inference were used to determine HIV-1 clusters, evolutionary dynamics, and virus migration rates between geographic regions. HIV-1 sub-subtype A1 (72.0%) was most common followed by subtype D (11.0%), unique recombinant forms (8.9%), subtype C (5.9%), CRF 21A2D (0.8%), subtype G (0.8%), CRF 16A2D (0.3%), and subtype B (0.3%). …”

Increased water intake reduces long-term renal and cardiovascular disease progression in experimental polycystic kidney disease by Priyanka S. Sagar (6169736)

“…Increasing water intake reduces renal cyst growth in the <i>pck</i> rat (a genetic ortholog of autosomal recessive PKD) but it is not clear if this beneficial effect is present in other models of PKD. …”

Controlling the Rigidity of Kinesin-Propelled Microtubules in an <i>In Vitro</i> Gliding Assay Using the Deep-Sea Osmolyte Trimethylamine <i>N</i>‑Oxide by Arif Md. Rashedul Kabir (7513523)

“…By varying the concentration of TMAO in the gliding assay, the rigidity of microtubules can be modulated over a wide range. Based on this strategy, we are able to reduce the persistence length of microtubules, a measure of microtubule rigidity, ∼8 fold by using TMAO at the concentration of 1.5 M. …”