Image2_Impact of CytoSorb and CKRT on hemodynamics in pediatric patients with septic shock: the PedCyto study.jpeg by Gabriella Bottari (9563402)

“…</p>Results<p>There were significant decreases in the Vasoactive Inotropic Score (VIS) and the Pediatric Logistic Organ Dysfunction 2 (PELOD-2) score at 72 and 96 h from the start of the CytoSorb therapy compared to baseline; the reductions were larger in the hemoadsorption group than in the control group (historical cohort). 28-day mortality was lower, although not significantly, in the hemoadsorption group when compared to the control group (5/17 [29%] vs. 8/13 [61%] OR 0.26 [95% CI: 0.05–1.2]; p = 0.08).…”

Mutation rates across 60 <i>C</i>. <i>elegans</i> genotypes stratified by mutation type: Base substitutions, indels, and structural variants. by Bettina Meier (274833)

“…Error bars show the 95% confidence intervals; large dots represent variants with 2-fold increased or decreased mutation rates over N2 wild-type which are statistically significant with a false discovery rate (FDR) below 5%. …”

Temporal evolution of urban EE in western China. by Dalai Ma (17847101)

“…Within them, the CCD of Chengdu is the highest, Chongqing has achieved the largest stage leap. (4) The global Moran’s I consistently remained positive and exhibited a tendency of initially rising and subsequently falling, indicating that the spatial aggregation effect of CCD-GFEE first increased and then decreased. (5) The CCD-GFEE driving factors are examined using the spatial econometric model, and it has been observed that the impact of population size and government intervention on CCD-GFEE is negative, while the impact of industrial structure, technological progress and economic level on the coupling and coordination of CCD-GFEE is positive. …”

Image1_Impact of CytoSorb and CKRT on hemodynamics in pediatric patients with septic shock: the PedCyto study.jpeg by Gabriella Bottari (9563402)

“…</p>Results<p>There were significant decreases in the Vasoactive Inotropic Score (VIS) and the Pediatric Logistic Organ Dysfunction 2 (PELOD-2) score at 72 and 96 h from the start of the CytoSorb therapy compared to baseline; the reductions were larger in the hemoadsorption group than in the control group (historical cohort). 28-day mortality was lower, although not significantly, in the hemoadsorption group when compared to the control group (5/17 [29%] vs. 8/13 [61%] OR 0.26 [95% CI: 0.05–1.2]; p = 0.08).…”

Supplementary Material for: Deleterious Effect of Hyperoxia at Birth on White Matter Damage in the Newborn Rat by Vottier G. (4126072)

“…We tested this hypothesis in rat pups delivered from normoxic pregnant rats, and by investigating an animal model based on protracted antenatal hypoxia in the pregnant rat and mimicking the main features of human WMD in rat pups. From embryonic day (E)5 to E21, the pregnant rats were placed in a chamber supplied with a gas mixture that either induced hypoxia (Fi<i>O</i>₂ = 10%) or maintained normoxia (Fi<i>O</i>₂ = 21%). …”

Graphic abstract of the study. by Donglin Yang (490406)

“…The results showed that the expression of circRNAs in serum exosomes of DN patients was significantly down-regulated, and hsa_circ_0006382 and hsa_circ_0019539 targeted the expression of FGF9 by binding to miR-34a-5p, miR-766-3p, miR-147a and miR-27a-3p. Further verification showed that the expression of FGF9 was decreased in renal tissues of DN patients (AUC = 0.902), and its recombinant protein could inhibit the expression of α-SMA and vimentin in high glucose-induced NRK-52E cells, indicating that activation of the circRNA/miRNA-FGF9 network promotes the EMT of renal tubular epithelial cells. …”

Spatial evolution trend of green finance index. by Dalai Ma (17847101)

“…Within them, the CCD of Chengdu is the highest, Chongqing has achieved the largest stage leap. (4) The global Moran’s I consistently remained positive and exhibited a tendency of initially rising and subsequently falling, indicating that the spatial aggregation effect of CCD-GFEE first increased and then decreased. (5) The CCD-GFEE driving factors are examined using the spatial econometric model, and it has been observed that the impact of population size and government intervention on CCD-GFEE is negative, while the impact of industrial structure, technological progress and economic level on the coupling and coordination of CCD-GFEE is positive. …”

Data Sheet 1_Antibiofilm potential of plant extracts: inhibiting oral microorganisms and Streptococcus mutans.pdf by Nomi Bartels (20997935)

“…P. cretica was able to inhibit and kill S. mutans at a concentration of 0.6 mg/ml, but its effectiveness in biofilm inhibition significantly decreased at 2.5 mg/ml.…”

Spatial and Seasonal Dynamic of Abundance and Distribution of Guanaco and Livestock: Insights from Using Density Surface and Null Models by Natalia M. Schroeder (513024)

“…The guanaco population reached its maximum annual size and spatial dispersion in spring-summer, decreasing up to 6.5 times in size and occupying few sites of the study area in fall-winter. …”

Genetic Variants of TPCN2 Associated with Type 2 Diabetes Risk in the Chinese Population by Yujuan Fan (2504536)

“…There was a 5.1% higher prevalence of the rs1551305 variant allele in type 2 diabetes individuals (A) compared with wild-type homozygous individuals (G). …”

Data_Sheet_1_Aberrant age-related alterations in spontaneous cortical activity in participants with cerebral palsy.PDF by Hannah Bergwell (16538259)

“…MEG data from a five-minute eyes closed resting-state paradigm were source imaged, and the power within the delta (2–4 Hz), theta (5–7 Hz), alpha (8–12 Hz), beta (15–29 Hz), and gamma (30–59 Hz) frequency bands were computed.…”

Table_3_Bacitracin Methylene Disalicylate Improves Intestinal Health by Modulating Its Development and Microbiota in Weaned Rabbits.docx by Yang Chen (9737)

“…The abundance of the genera Lachnospira, Erysipelotrichaceae (p-75-a5), Paraprevotellaceae (YRC22), Mogibacterium, Peptococcaceae (rc4-4), Anaerovibrio, Succinivibrio, and Sphaerochaeta increased in the BMDa and BZ groups (P < 0.05). …”

Conformational Mobility Profiling of the Hsp90-Cdc37 Complex. by Kristin Blacklock (447270)

“…<p>The NMSF profile of the Hsp90-Cdc37 complex (A) was obtained using the NMR structure (PDB ID 2K5B) of the complex between human Cdc37 (Cdc37-MD, original residue numbering 148–276) and human Hsp90-NTD (original residue numbering 14–223) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0086547#pone.0086547-Sreeramulu1" target="_blank">[25]</a>. …”

DataSheet_1_Transcriptomic Responses of Adult Versus Juvenile Atlantids to Ocean Acidification.pdf by Paula Ramos-Silva (572049)

“…Overall, this type of response was more common in adults (8.6% of all the genes) than in juveniles (3.9%), whereas a linear response with decreasing pH was more common in juveniles (7.7%) than in adults (4.5%). …”

Table 4_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Between 1990 and 2021, the malaria burden in the Comoros declined substantially, with age-standardized incidence (ASIR), prevalence (ASPR), mortality (ASMR), and DALY rates (ASDR) decreasing by over 85%. Decomposition analysis indicated that epidemiological changes played a pivotal role in reducing disease burden. …”

Initial weight values and correlation thresholds. by Qingnan Ji (22662198)

“…Integration efficiency increases by 18.7%, and computational complexity is significantly reduced, with average computation time decreased by 15.4%. User satisfaction also improves, with a 19.5% increase in experience ratings. …”

Detection of Plasma Protease Activity Using Microsphere-Cytometry Assays with <i>E</i>. <i>coli</i> Derived Substrates: VWF Proteolysis by ADAMTS13 by Shobhit Gogia (740889)

“…The substrate, expressed in <i>E</i>. <i>coli</i> as a fusion protein, contains the partial A2-domain of von Willebrand factor (VWF amino acids 1594–1670) that is mutated to include a single primary amine at the N-terminus and free cysteines at the C-terminus. …”

FIGURE 2 from Gigaxonin Suppresses Epithelial-to-Mesenchymal Transition of Human Cancer Through Downregulation of Snail by Mysore S. Veena (18126420)

“…<b>G,</b> Cells collected after 4 days of cisplatin treatment show decreased expression of GAN, and p16 (CDKN2A) and enhanced NFκB expression. …”

Table_1_Genome-Wide DNA Methylation Enhances Stemness in the Mechanical Selection of Tumor-Repopulating Cells.xlsx by Wei Huang (36889)

“…We found that genes with continuously increasing or decreasing methylation like CREB5/ADAMTS6/LMX1A may also affect the TRC screening process. …”

Table_1_Transcriptome analysis provides insights into the response of Lotus corniculatus roots to low-phosphorus stress.xlsx by Xin Zhao (71840)

“…Introduction<p>A lack of soil phosphorus (P) is a principal factor restricting the normal growth of Lotus corniculatus in the karst area of Guizhou Province, China, but the response mechanism of L. corniculatus under low-phosphorus stress remains unclear.…”