DataSheet_1_Comprehensive transcriptomic analysis of age-, dark-, and salt-induced senescence reveals underlying mechanisms and key regulators of leaf senescence in Zoysia japonica... by Lanshuo Wang (15995294)

“…In addition, we experimentally validated the senescence regulatory function of seven TFs including ZjNAP, ZjWRKY75, ZjARF2, ZjNAC1, ZjNAC083, ZjARF1, and ZjPIL5 using a protoplast-based senescence assay. This study provides new insight into the molecular mechanisms underlying Z. japonica leaf senescence and identifies potential genetic resources for enhancing its economic value by prolonging its green period.…”

Data Sheet 1_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx by Liqin Liang (652560)

“…Furthermore, the expression of SA and JA response-related genes (NbPR5 and NbPR12) was up-regulated in NbSOS1-13-silenced plants.…”

DataSheet1_Dynamic and balanced regulation of the thrABC operon gene for efficient synthesis of L-threonine.docx by Ruxin Hao (14703649)

“…The results showed that higher expression of thrC than thrAB enhanced cell growth and L-threonine production; however, L-threonine production decreased when the thrC proportion was too high. The highest L-threonine production was achieved when the expression intensity ratio of thrAB to thrC was 3:5. …”

The allosteric glycogen synthase kinase-3 inhibitor NP12 limits myocardial remodeling and promotes angiogenesis in an acute myocardial infarction model by Jugajyoti Baruah (3998135)

“…A key feature of acute myocardial infarction (AMI) is an alteration in cardiac architecture. …”

Image1_Modulation of the biological network of lumbar spinal stenosis by Tongdu Huoxue Decoction based on clinical metabolomics.PNG by Luhong Ji (14819746)

“…Regarding metabolomics, the levels of 41 differential metabolites were significantly different in the normal group (group NC) compared to group A, and those were significantly restored after treatment with THD, including chenodeoxycholic acid 3-sulfate, taurohyodeoxycholic acid, 3,5-Dihydroxy-4-methoxybenzoic acid, pinocembrin. …”

Data-driven exploration of new pressure-induced superconductivity in PbBi₂Te₄ by Ryo Matsumoto (527418)

“…The resistance decreased with increasing of the pressure, and pressure-induced superconducting transitions were discovered at 2.5 K under 10 GPa. …”

Presentation_1_Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis.PPTX by Wan-Chun Li (450324)

“…Loss of HK2 in HNSCC cells resulted in reduced cell (in vitro) and tumor (in vivo) growth, as well as decreased epithelial-mesenchymal transition–mediated cell movement; in contrast, HK2-deficient HNSCC cells exhibited greater sensitivity to chemotherapeutic drugs cisplatin and 5-fluorouracil but are more resistant to photodynamic therapy, indicating that HK2 expression could selectively define treatment sensitivity in HNSCC cells. …”

Image_4_Low-Dose Antibiotic Prophylaxis Induces Rapid Modifications of the Gut Microbiota in Infants With Vesicoureteral Reflux.TIF by William Morello (10984251)

“…</p><p>Conclusions: In infants with VUR, even a short exposure to CAP definitely alters the GM composition, with increased relative abundance of opportunistic pathogens and decreased proportions of health-promoting taxa. …”

Data Sheet 3_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx by Liqin Liang (652560)

“…Furthermore, the expression of SA and JA response-related genes (NbPR5 and NbPR12) was up-regulated in NbSOS1-13-silenced plants.…”

Data_Sheet_1_Threshold Reaction of Soil Arthropods to Simulative Nitrogen Deposition in Urban Green Spaces.pdf by Lingzi Mo (11645293)

“…Although higher doses of N addition showed adverse effects on soil fauna communities, low N inputs increased the soil fauna diversity and richness, especially at 5–10 cm depth. A threshold effect appears to exist low nitrogen addition (<25 kg N ha^–1) did not affect negatively pedofauna structure and composition, while in the range from these values up to 50 kg N ha^–1, the composition of the soil fauna underwent major changes confirmed by the decline of biodiversity indices. …”

Image_1_Fenofibrate Ameliorated Systemic and Retinal Inflammation and Modulated Gut Microbiota in High-Fat Diet-Induced Mice.pdf by Xue Wang (102830)

“…<p>Fenofibrate, as a lipid-lowering drug, has been reported to have a protective effect on the retina independent with plasma lipid levels. …”

Table3_Metabolic Consequences of Developmental Exposure to Polystyrene Nanoplastics, the Flame Retardant BDE-47 and Their Combination in Zebrafish.DOCX by Raphaël Chackal (12093191)

“…Conversely, molecular gene expression data pointed to a negative interaction, as co-exposure of high PS generally abolished the induction of gene expression in response to BDE-47. …”

Table3_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx by Ye Yang (297214)

“…RT-qPCR revealed that the CKO mice presented a significantly less transcription of Sp5, an important element of the Wnt signaling pathway.…”

Data_Sheet_1_Mendelian randomization shows causal effects of birth weight and childhood body mass index on the risk of frailty.DOCX by Junhao Cui (18601693)

“…</p>Results<p>Genetically predicted one standard deviation (SD) increase in own birth weight, but not offspring birth weight (maternal-specific), was linked to a decreased frailty index (β per SD increase = −0.068, 95%CI = −0.106 to −0.030, p = 3.92E-04). …”

Fluorogenic Dimers as Bright Switchable Probes for Enhanced Super-Resolution Imaging of Cell Membranes by Ilya O. Aparin (4435837)

“…In these probes, the two cyanine units connected with a linker were modified at their extremities with low-affinity membrane anchors. …”

Presentation_1_Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis.PPTX by Wan-Chun Li (450324)

“…Loss of HK2 in HNSCC cells resulted in reduced cell (in vitro) and tumor (in vivo) growth, as well as decreased epithelial-mesenchymal transition–mediated cell movement; in contrast, HK2-deficient HNSCC cells exhibited greater sensitivity to chemotherapeutic drugs cisplatin and 5-fluorouracil but are more resistant to photodynamic therapy, indicating that HK2 expression could selectively define treatment sensitivity in HNSCC cells. …”

Table_2_Transcriptional changes in the gilthead seabream (Sparus aurata) skin in response to ultraviolet B radiation exposure.xlsx by Ricardo N. Alves (8839895)

“…S. aurata juveniles were exposed for 43 days to two experimental groups: 1) UVB (daily dose, 6 kJ m^-2; representing levels between 5 and 7 m depth); 2) Unirradiated treatment, used as a control. …”

Fluorogenic Dimers as Bright Switchable Probes for Enhanced Super-Resolution Imaging of Cell Membranes by Ilya O. Aparin (4435837)

“…In these probes, the two cyanine units connected with a linker were modified at their extremities with low-affinity membrane anchors. …”

DataSheet1_Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment.DOCX by Zhenzhen Zhu (817819)

“…Higher expression of type 2 inflammatory molecules (CCL13, IGHE, CCL18, CCL23, CCR3, and CLC) with lower levels of LACRT, PPDPFL, DES, C6, MUC5B, and SCGB3A1 were related to a stronger clinical response to GC. …”

Table1_Tissue explants as tools for studying the epigenetic modulation of the GH-IGF-I axis in farmed fish.docx by Erick Perera (636690)

“…In particular, the expression of igfbp2a was increased and that of igfbp4, ghri and ghrii was decreased by DAC as well as by genistein, which is suggestive of impaired growth. …”