Dose-Dependent Effect of Estrogen Suppresses the Osteo-Adipogenic Transdifferentiation of Osteoblasts via Canonical Wnt Signaling Pathway by Bo Gao (106513)

“…<div><p>Fat infiltration within marrow cavity is one of multitudinous features of estrogen deficiency, which leads to a decline in bone formation functionality. The origin of this fat is unclear, but one possibility is that it is derived from osteoblasts, which transdifferentiate into adipocytes that produce bone marrow fat. …”

Data_Sheet_1_Social media interventions for autistic individuals: Systematic review.pdf by Elia Gabarron (14693665)

“…Results were synthesized and sorted by quality of evidence.</p>Results<p>A total of nine articles were included in this review: eight primary studies (five non-randomized interventions and three randomized interventions) and one systematic review. …”

Tradeoffs in resistance to two antibiotics. by Ellsworth M. Campbell (313943)

“…<p>Plot represents resistance as the minimal inhibitory concentration (<i>MICA and MICB</i>) to the pair of drugs A and B. The three resistant bacteria <i>R</i>₁ (▴), <i>R</i>₂ (▪), and <i>R</i>₃ (•) are depicted. …”

Image1_Honokiol Inhibits Atrial Metabolic Remodeling in Atrial Fibrillation Through Sirt3 Pathway.TIF by Guang Zhong Liu (12255398)

“…Meanwhile, AF induced an increase of the acetylation level in long-chain acyl-CoA dehydrogenase (LCAD), AceCS2 and GDH, following decreasing of activity of it enzymes, resulting in abnormal alterations of metabolites and reducing of ATP, which was inhibited by HL. …”

Table9_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx by Ye Yang (297214)

“…RT-qPCR revealed that the CKO mice presented a significantly less transcription of Sp5, an important element of the Wnt signaling pathway.…”

Table6_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx by Ye Yang (297214)

“…RT-qPCR revealed that the CKO mice presented a significantly less transcription of Sp5, an important element of the Wnt signaling pathway.…”

Data_Sheet_1_Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis.xlsx by Su Liu (1965895)

“…Prevotella could distinguish between OA patients and healthy people with a better diagnostic power (AUC = 77.5%, p < 0.001, 95% CI: 66.9–88.1%). …”

Table1_Honokiol Inhibits Atrial Metabolic Remodeling in Atrial Fibrillation Through Sirt3 Pathway.docx by Guang Zhong Liu (12255398)

“…Meanwhile, AF induced an increase of the acetylation level in long-chain acyl-CoA dehydrogenase (LCAD), AceCS2 and GDH, following decreasing of activity of it enzymes, resulting in abnormal alterations of metabolites and reducing of ATP, which was inhibited by HL. …”

DataSheet_1_Impact of the COVID-19 pandemic on cervical cancer screening participation, abnormal cytology prevalence and screening interval in Catalonia.docx by Claudia Robles (14970465)

“…Abnormal cytology prevalence was 1.4 times higher than expected in 2020 and 2021, with variations by age (range=1.1–1.5). From June 2020 onwards, the screening interval trend significantly changed from an increase of 0.59 to 3.57 months per year, resulting in a median time of 48 months by December 2021.…”

Data_Sheet_1_Kaolin Film Increases Gas Exchange Parameters of Coffee Seedlings During Transference From Nursery to Full Sunlight.docx by Deivisson Pelegrino de Abreu (11917769)

“…In Coffea plants, KF decreased the T_leaf up to 6.7°C/5.6°C and reduced the CWSI. …”

Presentation1_Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection.pdf by Imre Vörös (10175693)

“…Furthermore, in a translational porcine closed-chest acute myocardial infarction model, ischemic preconditioning increased plasma SST-like immunoreactivity. …”

Image_2_Fenofibrate Ameliorated Systemic and Retinal Inflammation and Modulated Gut Microbiota in High-Fat Diet-Induced Mice.pdf by Xue Wang (102830)

“…<p>Fenofibrate, as a lipid-lowering drug, has been reported to have a protective effect on the retina independent with plasma lipid levels. …”

DataSheet1_CYP2D6 gene polymorphism and apatinib affect the metabolic profile of fluvoxamine.docx by Zhize Ye (13583515)

“…The results demonstrated that the relative clearance rates of CYP2D6.A5V, V104A, D337G, F164L, V342M, R440C and R497C increased significantly compared with CYP2D6.1, ranging from 153.626% ± 6.718% to 394.310% ± 33.268%. …”

Data Sheet 6_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx by Liqin Liang (652560)

“…Furthermore, the expression of SA and JA response-related genes (NbPR5 and NbPR12) was up-regulated in NbSOS1-13-silenced plants.…”

Data_Sheet_1_From Raffinose Family Oligosaccharides to Sucrose and Hexoses: Gene Expression Profiles Underlying Host-to-Nematode Carbon Delivery in Cucumis sativus Roots.PDF by Xingyi Wang (4025135)

“…Consistently, stachyose level was significantly increased by ∼2.5 times at the early stage but reduced at the late stage of infection in comparison with the uninfected roots, with a similar trend found for raffinose and galactinol. …”

Table_2_From Raffinose Family Oligosaccharides to Sucrose and Hexoses: Gene Expression Profiles Underlying Host-to-Nematode Carbon Delivery in Cucumis sativus Roots.pdf by Xingyi Wang (4025135)

“…Consistently, stachyose level was significantly increased by ∼2.5 times at the early stage but reduced at the late stage of infection in comparison with the uninfected roots, with a similar trend found for raffinose and galactinol. …”

Table_1_Fenofibrate Ameliorated Systemic and Retinal Inflammation and Modulated Gut Microbiota in High-Fat Diet-Induced Mice.docx by Xue Wang (102830)

“…<p>Fenofibrate, as a lipid-lowering drug, has been reported to have a protective effect on the retina independent with plasma lipid levels. …”

DataSheet1_Elevated Serum Uric Acid is Associated With Poor Survival in Advanced HCC Patients and Febuxostat Improves Prognosis in HCC Rats.docx by Le Wu (4529626)

“…On this basis, febuxostat, a specific inhibitor of xanthine oxidase (XOD), was used to interfere with HCC rats.…”

Table1_Metabolic Consequences of Developmental Exposure to Polystyrene Nanoplastics, the Flame Retardant BDE-47 and Their Combination in Zebrafish.DOCX by Raphaël Chackal (12093191)

“…Conversely, molecular gene expression data pointed to a negative interaction, as co-exposure of high PS generally abolished the induction of gene expression in response to BDE-47. …”

Clock function in EO neurons is not required for synchronization to temperature cycles in constant darkness. by Clara Lorber (14106749)

“…Same flies as in panel B and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010487#pgen.1010487.g005" target="_blank">Fig 5C</a>.…”