Image_3_Thermoresponsive Copolymer Nanovectors Improve the Bioavailability of Retrograde Inhibitors in the Treatment of Leishmania Infections.tif by Evan Craig (4025492)

“…It is, therefore, imperative that more effective drug formulations with decreased toxicity profiles are developed. Previous studies had shown that 2-(((5-Methyl-2-thienyl)methylene)amino)-N-phenylbenzamide (also called Retro-2) has efficacy against Leishmania infections. …”

Data_Sheet_1_Unveiling the Impact of Morphine on Tamoxifen Metabolism in Mice in vivo.pdf by Florian Gabel (8475108)

“…After administration, tamoxifen is converted into two more potent antitumor compounds, 4OH-tamoxifen and endoxifen by the CYP3A4/5 and 2D6 enzymes in human. These active compounds are inactivated by the same UDP-glucuronosyltransferase isoforms as those involved in the metabolism of morphine. …”

Image 1_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff by Songtao Li (186776)

“…In comparison to the reference group Q1, groups Q5 had adjusted OR values of 0.63 (95%CI: 0.52–0.76, p < 0.01). …”

Image_4_Gypenosides Prevent and Dissolve Cholesterol Gallstones by Modulating the Homeostasis of Cholesterol and Bile Acids.tif by Qian Zhuang (621842)

“…GPs increased the hepatic expression of genes encoding the cytochrome P450 (Cyp) enzymes Cyp7a1, Cyp7b1, and Cyp8b1, while decreasing the hepatic expression of genes encoding the adenosine triphosphate-binding cassette (Abc) transporters Abcg5 and Abcg8. …”

Image 2_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff by Songtao Li (186776)

“…In comparison to the reference group Q1, groups Q5 had adjusted OR values of 0.63 (95%CI: 0.52–0.76, p < 0.01). …”

DataSheet3_Integrative Analysis of Long- and Short-Read Transcriptomes Identify the Regulation of Terpenoids Biosynthesis Under Shading Cultivation in Oenanthe javanica.docx by Kai Feng (502124)

“…<p>Water dropwort (Oenanthe javanica) is a popular vegetable with high nutritional value and distinctive flavor. …”

Message for SAG1 and BAG1 ±ATc for 4 or 24 hours of culture and immunofluorescence analyses for BAG1, SAG1, SRS9, and Dolichos. by Samuel L. Hutson (236870)

“…<p>(A) Increased message for BAG1 and decreased message for SAG1 -ATc at 24 hours. …”

Data_Sheet_1_The Sharp Rise in the Use of Low- and No-Calorie Sweeteners in Non-Alcoholic Beverages in Slovenia: An Update Based on 2020 Data.docx by Edvina Hafner (11728730)

“…The use of LNCS increased from 13.2% in 2017 and 15.5% in 2019 to 20.2% in 2020, with a major growth in soft drinks (16.8, 19.6, and 26.7%, respectively). …”

Supplementary Material for: Endotoxin Adsorbent Therapy in Severe COVID-19 Pneumonia by Peerapornratana S. (10651337)

“…<b><i>Methods:</i></b> We conducted a retrospective observational study in COVID-19 patients who received EA therapy at the King Chulalongkorn Memorial Hospital, Bangkok, Thailand, between March 13 and April 17, 2020. …”

Dietary Fe₃O₄ Nanozymes Prevent the Injury of Neurons and Blood–Brain Barrier Integrity from Cerebral Ischemic Stroke by Bing Chun Yan (8152314)

“…<i>Ex vivo</i> analysis shows that PEG-modified Fe₃O₄ nanozymes localize in the cerebral vasculature, ameliorate local redox state with decreased malondialdehyde and increased Cu/Zn SOD, and facilitate blood–brain-barrier recovery by elevating ZO-1 and Claudin-5 in the hippocampus. …”

Self-Healable, Recyclable, and Strengthened Epoxidized Natural Rubber/Carboxymethyl Chitosan Biobased Composites with Hydrogen Bonding Supramolecular Hybrid Networks by Chuanhui Xu (516106)

“…To solve this problem, in this paper, we constructed a hydrogen bonding supramolecular hybrid network by incorporating carboxymethyl chitosan (CMCS) into epoxidized natural rubber (ENR) through a solution-mixing method. …”

Hesperetin Alleviates the Inhibitory Effects of High Glucose on the Osteoblastic Differentiation of Periodontal Ligament Stem Cells by So Yeon Kim (196803)

“…<div><p>Hesperetin (3′,5,7-trihydroxy-4-methoxyflavanone) is a metabolite of hesperidin (hesperetin-7-O-rutinoside), which belongs to the flavanone subgroup and is found mainly in citrus fruits. …”

Data_Sheet_1_P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death in vitro and in vivo.PDF by Chao Gu (402478)

“…Furthermore, in LPS-treated microglia, P7C3-pretreatment decreased the toxicity of conditioned media to MES23.5 cells (a dopaminergic (DA) cell line). …”

Insect Pollinated Crops, Insect Pollinators and US Agriculture: Trend Analysis of Aggregate Data for the Period 1992–2009 by Nicholas W. Calderone (162884)

“…Trend analysis demonstrates that US producers have a continued and significant need for insect pollinators and that a diminution in managed or wild pollinator populations could seriously threaten the continued production of insect pollinated crops and crops grown from seeds resulting from insect pollination.…”

Table_2_Ontogeny and brooding strategy of the early Cambrian arthropod Isoxys minor from the Qingjiang biota.XLSX by Jiaxin Ma (3847726)

“…<p>†Isoxys is a worldwide distributed bivalved arthropod known almost exclusively from Cambrian Burgess Shale-type Lagerstätten. …”

Partitioning Detectability Components in Populations Subject to Within-Season Temporary Emigration Using Binomial Mixture Models by Katherine M. O’Donnell (702807)

“…We fit our model and a standard binomial mixture model to counts of terrestrial salamanders surveyed at 40 sites during 3–5 surveys each spring and fall 2010–2012. …”

DataSheet_1_Immunophenotype associated with high sustained antibody titers against enzyme replacement therapy in infantile-onset Pompe disease.pdf by Ankit K. Desai (9214082)

“…B cells were increased in HSAT patients with a decreased fraction of unswitched memory B cells. …”

Image_6_Identification, Characterization, and Expression Profile Analysis of the mTERF Gene Family and Its Role in the Response to Abiotic Stress in Barley (Hordeum vulgare L.).JPE... by Tingting Li (10553)

“…In this study, we identified 60 mTERFs in the barley genome (HvmTERFs) through a comprehensive search against the most updated barley reference genome, Morex V2. …”

Data_Sheet_1_Soil Bacterial Community in the Multiple Cropping System Increased Grain Yield Within 40 Cultivation Years.docx by Tao Chen (75911)

“…The molecular ecological network indicated that the stability of the bacterial community decreased across the cultivation years, which may result in a decline of farmland yields in multiple cropping system> 40 years. …”

Image_4_Thermoresponsive Copolymer Nanovectors Improve the Bioavailability of Retrograde Inhibitors in the Treatment of Leishmania Infections.tif by Evan Craig (4025492)

“…It is, therefore, imperative that more effective drug formulations with decreased toxicity profiles are developed. Previous studies had shown that 2-(((5-Methyl-2-thienyl)methylene)amino)-N-phenylbenzamide (also called Retro-2) has efficacy against Leishmania infections. …”